Michelle M Armstrong

A potent and selective inhibitor targeting human and murine 12/15-LOX.

A. Jadhav, A. Simeonov, T. Holman, 2016, Bioorganic & medicinal chemistry.

Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1.

A. Jadhav, A. Simeonov, Victor A Kenyon, 2010, Journal of medicinal chemistry.

Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase.

A. Jadhav, A. Simeonov, Victor A Kenyon, 2011, Journal of medicinal chemistry.

Human 15-LOX-1 active site mutations alter inhibitor binding and decrease potency.

Joshua D Deschamps, T. Holman, C. Kalyanaraman, 2016, Bioorganic & medicinal chemistry.

Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2.

Adam Yasgar, A. Jadhav, A. Simeonov, 2021, Bioorganic & medicinal chemistry.