Misako Fukasawa

Effect of a New Inhibitor of the Synthesis of 20-HETE on Cerebral Ischemia Reperfusion Injury

S. Okuyama, S. Nakaike, R. Roman, 2006, Stroke.

Continuous inhibition of 20-HETE synthesis by TS-011 improves neurological and functional outcomes after transient focal cerebral ischemia in rats

S. Nakaike, S. Yoshida, N. Miyata, 2007, Neuroscience Research.

Metabolism of N,N-dipropyl-2-[4-methoxy-3-(2-phenyl-ethoxy)-phenyl]-ethyl-amine-monohydrochloride (NE-100), a novel sigma ligand: contribution of cytochrome P450 forms involved in the formation of individual metabolites in human liver and small intestine.

K. Nagata, Y. Yamazoe, Masato Nakamura, 2003, Drug metabolism and pharmacokinetics.

Discovery of MGS0274, an ester prodrug of a metabotropic glutamate receptor 2/3 agonist with improved oral bioavailability.

S. Chaki, H. Hikichi, N. Miyakoshi, 2020, European journal of medicinal chemistry.

Safety and pharmacokinetic profiles of MGS0274 besylate (TS‐134), a novel metabotropic glutamate 2/3 receptor agonist prodrug, in healthy subjects

Brian Marcy, S. Chaki, S. Okuyama, 2020, British journal of clinical pharmacology.

Preclinical disposition of MGS0274 besylate, a prodrug of a potent group II metabotropic glutamate receptor agonist MGS0008 for the treatment of schizophrenia

K. Iwata, Motoki Ochi, J. Yamaguchi, 2019, Pharmacology research & perspectives.