X. Barbeau

发表

tRNAGlu Increases the Affinity of Glutamyl-tRNA Synthetase for Its Inhibitor Glutamyl-Sulfamoyl-Adenosine, an Analogue of the Aminoacylation Reaction Intermediate Glutamyl-AMP: Mechanistic and Evolutionary Implications

P. Lagüe, R. Chěnevert, J. Lapointe, 2015, PloS one.

Extended Linkers Improve the Detection of Protein-protein Interactions (PPIs) by Dihydrofolate Reductase Protein-fragment Complementation Assay (DHFR PCA) in Living Cells.

Isabelle Gagnon-Arsenault, C. Landry, Philippe C. Després, 2018, Molecular & cellular proteomics : MCP.

Discovery of a non-estrogenic irreversible inhibitor of 17β-hydroxysteroid dehydrogenase type 1 from 3-substituted-16β-(m-carbamoylbenzyl)-estradiol derivatives.

P. Lagüe, D. Poirier, D. Ayan, 2014, Journal of medicinal chemistry.

Characterization of the structure, dynamics and allosteric pathways of human NPP1 in its free form and substrate-bound complex from molecular modeling.

P. Lagüe, P. Mathieu, J. Paquin, 2017, Molecular bioSystems.

Antibiotic resistance due to an unusual ColE1-type replicon plasmid in Aeromonas salmonicida.

J. Emond‐Rheault, S. Charette, P. Lagüe, 2016, Microbiology.

Identification of fused 16β,17β-oxazinone-estradiol derivatives as a new family of non-estrogenic 17β-hydroxysteroid dehydrogenase type 1 inhibitors.

P. Lagüe, D. Poirier, R. Maltais, 2015, European journal of medicinal chemistry.

Impact of structural modifications at positions 13, 16 and 17 of 16β-(m-carbamoylbenzyl)-estradiol on 17β-hydroxysteroid dehydrogenase type 1 inhibition and estrogenic activity

P. Lagüe, D. Poirier, R. Maltais, 2016, The Journal of Steroid Biochemistry and Molecular Biology.

Interfacial supramolecular biomimetic epoxidation catalysed by cyclic dipeptides

P. Lagüe, N. Voyer, Pierre-Luc Boudreault, 2017 .

Revisiting the Juliá-Colonna enantioselective epoxidation: supramolecular catalysis in water.

Xavier Barbeau, Patrick Lagüe, Normand Voyer, 2017, Chemical communications.

Aeromonas salmonicida Ati2 is an effector protein of the type three secretion system.

S. Charette, P. Lagüe, M. Reith, 2013, Microbiology.

Chemical synthesis of C3-oxiranyl/oxiranylmethyl-estrane derivatives targeted by molecular modeling and tested as potential inhibitors of 17β-hydroxysteroid dehydrogenase type 1

D. Poirier, J. Roy, R. Maltais, 2018, Steroids.

CRISPR-induced deletion with SaCas9 restores dystrophin expression in dystrophic models in vitro and in vivo

J. Rousseau, D. Ouellet, Dominique L. Ouellet, 2018, bioRxiv.

Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia

D. Meyerholz, S. Krishnamurthy, C. Wohlford-Lenane, 2019, Nature Communications.

Membrane permeabilizing amphiphilic peptide delivers recombinant transcription factor and CRISPR-Cas9/Cpf1 ribonucleoproteins in hard-to-modify cells

A. Garnier, D. Roy, David Guay, 2018, PloS one.

Quinazoline‐4‐piperidine sulfamides are specific inhibitors of human NPP1 and prevent pathological mineralization of valve interstitial cells

P. Lagüe, J. Sévigny, Marie-Chloé Boulanger, 2015, British journal of pharmacology.

Sédation-analgésie pré-hospitalière: Enquête nationale, Mars 1998

X. Barbeau, G. Mehu, B. Michielini, 2000 .

Peroxidase Activity and Involvement in the Oxidative Stress Response of Roseobacter denitrificans Truncated Hemoglobin

P. Lagüe, M. Couture, Yaya Wang, 2015, PloS one.

Corrigendum to “Efficient Restoration of the Dystrophin Gene Reading Frame and Protein Structure in DMD Myoblasts Using the CinDel Method”

J. Rousseau, P. Lagüe, P. Chapdelaine, 2016, Molecular therapy. Nucleic acids.

Efficient Restoration of the Dystrophin Gene Reading Frame and Protein Structure in DMD Myoblasts Using the CinDel Method

J. Rousseau, P. Lagüe, P. Chapdelaine, 2016, Molecular therapy. Nucleic acids.

Novel chiral N,N′-dimethyl-1,4-piperazines with metal binding abilities

N. Voyer, Pierre-Luc Boudreault, S. Cardinal, 2015 .

Synthesis and biological evaluation of novel quinazoline-4-piperidinesulfamide derivatives as inhibitors of NPP1.

P. Lagüe, Marie-Chloé Boulanger, P. Mathieu, 2018, European journal of medicinal chemistry.

Lobaric acid and pseudodepsidones inhibit NF-κB signaling pathway by activation of PPAR-γ.

P. Lagüe, N. Voyer, Katy Vaillancourt, 2018, Bioorganic & medicinal chemistry.

Discovery of a sulfamate-based steroid sulfatase inhibitor with intrinsic selective estrogen receptor modulator properties.

P. Lagüe, D. Poirier, R. Maltais, 2016, European journal of medicinal chemistry.

Design and synthesis of dansyl-labeled inhibitors of steroid sulfatase for optical imaging.

Jean-Philippe Lambert, D. Poirier, J. Roy, 2020, Bioorganic & medicinal chemistry.

Insight into the mode of action and selectivity of PBRM, a covalent steroidal inhibitor of 17&bgr;‐hydroxysteroid dehydrogenase type 1

P. Lagüe, D. Poirier, J. Roy, 2017, Biochemical pharmacology.

Stereocontrolled approach to bromofluoroalkenes and their use for the synthesis of tri- and tetrasubstituted fluoroalkenes.

P. Champagne, J. Paquin, X. Barbeau, 2009, Organic letters.

ConfBuster: Open-Source Tools for Macrocycle Conformational Search and Analysis

Xavier Barbeau, Antony T. Vincent, Patrick Lagüe, 2018 .

Antibiotic resistance due to an unusual ColE1-type replicon plasmid in Aeromonas salmonicida.

A. T. Vincent, S. Charette, P. Lagüe, 2016, Microbiology.

Extended Linkers Improve the Detection of Protein-protein Interactions (PPIs) by Dihydrofolate Reductase Protein-fragment Complementation Assay (DHFR PCA) in Living Cells*

Isabelle Gagnon-Arsenault, C. Landry, Philippe C. Després, 2017, Molecular & Cellular Proteomics.

Revisiting the Juliá-Colonna enantioselective epoxidation: supramolecular catalysis in water.

P. Lagüe, N. Voyer, X. Barbeau, 2017, Chemical communications.

The I427T neuraminidase (NA) substitution, located outside the NA active site of an influenza A(H1N1)pdm09 variant with reduced susceptibility to NA inhibitors, alters NA properties and impairs viral fitness

P. Lagüe, G. Boivin, Yacine Abed, 2017, Antiviral research.

Extended linkers improve the detection of protein-protein interactions (PPIs) by dihydrofolate reductase protein-fragment complementation assay (DHFR PCA) in living cells

Isabelle Gagnon-Arsenault, C. Landry, Philippe C. Després, 2018, Molecular & Cellular Proteomics.

Impact of structural modifications at positions 13, 16 and 17 of 16β-(m-carbamoylbenzyl)-estradiol on 17β-hydroxysteroid dehydrogenase type 1 inhibition and estrogenic activity

P. Lagüe, D. Poirier, R. Maltais, 2016, The Journal of Steroid Biochemistry and Molecular Biology.