K. Rutten

发表

Effects of the NOP receptor agonist Ro65-6570 on the acquisition of opiate- and psychostimulant-induced conditioned place preference in rats.

T. Tzschentke, J. de Vry, K. Rutten, 2010, European journal of pharmacology.

Alterations in brain cholesterol metabolism in the APPSLxPS1mut mouse, a model for Alzheimer's disease.

E. Sijbrands, F. Kuipers, V. Bloks, 2010, Journal of Alzheimer's disease : JAD.

Cancer-induced Bone Pain Impairs Burrowing Behaviour in Mouse and Rat

T. Christoph, A. Heegaard, C. Appel, 2019, In Vivo.

Selectivity profiling of NOP, MOP, DOP and KOP receptor antagonists in the rat spinal nerve ligation model of mononeuropathic pain

T. Tzschentke, T. Christoph, W. Schröder, 2018, European journal of pharmacology.

Pharmacogenomic study of the role of the nociceptin/orphanin FQ receptor and opioid receptors in diabetic hyperalgesia.

K. Schiene, T. Tzschentke, T. Christoph, 2014, European journal of pharmacology.

The nociceptin/orphanin FQ receptor system as a target to alleviate cancer‐induced bone pain in rats: Model validation and pharmacological evaluation

T. Tzschentke, T. Christoph, A. Heegaard, 2019, British journal of pharmacology.

Cross-centre replication of suppressed burrowing behaviour as an ethologically relevant pain outcome measure in the rat: a prospective multicentre study.

R. Treede, C. Svensson, A. Rice, 2016, Pain.

Burrowing as a non‐reflex behavioural readout for analgesic action in a rat model of sub‐chronic knee joint inflammation

K. Schiene, S. Read, T. Christoph, 2014, European journal of pain.

Critical Evaluation of the Use of Extinction Paradigms for the Assessment of Opioid-Induced Conditioned Place Preference in Rats

T. Tzschentke, J. de Vry, E. L. van der Kam, 2011, Pharmacology.

Cerebral Accumulation of Dietary Derivable Plant Sterols does not Interfere with Memory and Anxiety Related Behavior in Abcg5−/− Mice

A. Blokland, E. Sijbrands, J. Prickaerts, 2011, Plant foods for human nutrition.

Pharmacological blockade or genetic knockout of the NOP receptor potentiates the rewarding effect of morphine in rats.

T. Tzschentke, J. de Vry, K. Rutten, 2010, Drug and alcohol dependence.

The selective PDE5 inhibitor, sildenafil, improves object memory in Swiss mice and increases cGMP Levels in hippocampal slices

A. Blokland, J. Vente, J. Prickaerts, 2005, Behavioural Brain Research.

Selective phosphodiesterase inhibitors: a promising target for cognition enhancement

A. Blokland, J. Prickaerts, O. Reneerkens, 2008, Psychopharmacology.

Rolipram reverses scopolamine-induced and time-dependent memory deficits in object recognition by different mechanisms of action

A. Blokland, J. Prickaerts, K. Rutten, 2006, Neurobiology of Learning and Memory.

Beyond Erectile Dysfunction: Understanding PDE5 Activity In The Central Nervous System

J. Prickaerts, O. Reneerkens, H. Steinbusch, 2014 .

Conventional Behavioral Models and Readouts in Drug Discovery: The Importance of Improving Translation

K. Rutten, 2021, Modern CNS Drug Discovery.

Object recognition testing: Rodent species, strains, housing conditions, and estrous cycle

A. Blokland, J. Prickaerts, S. Akkerman, 2012, Behavioural Brain Research.

The effects of phosphodiesterase inhibition on memory

K. Rutten, 2007 .

Cross-centre replication of suppressed burrowing behaviour as an ethologically relevant pain outcome measure in the rat: a prospective multicentre study

R. Treede, C. Svensson, A. Rice, 2016, Pain.

Electrophysiological characterization of activation state-dependent Cav2 channel antagonist TROX-1 in spinal nerve injured rats

K. Schiene, A. Dickenson, N. Damann, 2015, Neuroscience.

No effect of acute tryptophan depletion on phosphodiesterase inhibition–related improvements of short‐term object memory in male Wistar rats

A. Blokland, J. Prickaerts, S. Akkerman, 2013, Acta psychiatrica Scandinavica.

Effects of the cognition impairer MK-801 on learning and memory in mice and rats

A. Blokland, K. Rutten, C. Erb, 2011, Behavioural Brain Research.

Liver X receptor activation restores memory in aged AD mice without reducing amyloid

A. Blokland, E. Sijbrands, J. Prickaerts, 2011, Neurobiology of Aging.

Improved Long-Term Memory via Enhancing cGMP-PKG Signaling Requires cAMP-PKA Signaling

R. D'Hooge, A. Palmeri, A. Blokland, 2014, Neuropsychopharmacology.

Chronic phosphodiesterase type 2 inhibition improves memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease

A. Sierksma, J. Prickaerts, H. Steinbusch, 2013, Neuropharmacology.

Phosphodiesterase type 5 (PDE5) inhibition improves object recognition memory: Indications for central and peripheral mechanisms

F. Menniti, A. Blokland, J. Prickaerts, 2012, Neurobiology of Learning and Memory.

Phosphodiesterase Inhibitors Enhance Object Memory Independent of Cerebral Blood Flow and Glucose Utilization in Rats

P. Kelly, A. Blokland, J. Prickaerts, 2009, Neuropsychopharmacology.

Automated scoring of novel object recognition in rats

K. Rutten, O. A. H. Reneerkens, H. Hamers, 2008, Journal of Neuroscience Methods.

Time-dependent involvement of cAMP and cGMP in consolidation of object memory: studies using selective phosphodiesterase type 2, 4 and 5 inhibitors.

F. J. van der Staay, A. Blokland, J. Prickaerts, 2007, European journal of pharmacology.

Experimental design and reporting standards for improving the internal validity of pre-clinical studies in the field of pain: Consensus of the IMI-Europain consortium

Gillian L. Currie, R. Treede, M. Macleod, 2015, Scandinavian journal of pain.

The novel selective PDE9 inhibitor BAY 73-6691 improves learning and memory in rodents

K. Reymann, F. J. van der Staay, A. Blokland, 2008, Neuropharmacology.

Inhibition of phoshodiesterase type 2 or type 10 reverses object memory deficits induced by scopolamine or MK-801

T. Hage, A. Blokland, J. Prickaerts, 2013, Behavioural Brain Research.

The PDE4 inhibitor rolipram reverses object memory impairment induced by acute tryptophan depletion in the rat

A. Blokland, C. Lieben, K. Rutten, 2007, Psychopharmacology.

Enhanced long-term depression and impaired reversal learning in phosphodiesterase 4B-knockout (PDE4B −/−) mice

A. Blokland, J. Prickaerts, Melissa G. Works, 2011, Neuropharmacology.

Sub-chronic rolipram treatment leads to a persistent improvement in long-term object memory in rats

A. Blokland, J. Prickaerts, H. Rosenbrock, 2008, Neurobiology of Learning and Memory.

The mGluR5 antagonist 2‐methyl‐6‐(phenylethynyl)‐pyridine (MPEP) potentiates conditioned place preference induced by various addictive and non‐addictive drugs in rats

T. Tzschentke, J. de Vry, E. L. van der Kam, 2011, Addiction biology.

Phosphodiesterase 2 and 5 inhibition attenuates the object memory deficit induced by acute tryptophan depletion.

A. Blokland, J. Prickaerts, S. Akkerman, 2008, European journal of pharmacology.

Enhanced long‐term potentiation and impaired learning in phosphodiesterase 4D‐knockout (PDE4D−/−) mice

A. Blokland, Melissa G. Works, L. Santarelli, 2008, The European journal of neuroscience.

Selective PDE inhibitors rolipram and sildenafil improve object retrieval performance in adult cynomolgus macaques

A. Blokland, J. Prickaerts, J. Vivian, 2007, Psychopharmacology.

Standard analgesics reverse burrowing deficits in a rat CCI model of neuropathic pain, but not in models of type 1 and type 2 diabetes-induced neuropathic pain

A. Pekcec, H. Doods, T. Christoph, 2018, Behavioural Brain Research.

Pharmacological validation of a refined burrowing paradigm for prediction of analgesic efficacy in a rat model of sub‐chronic knee joint inflammation

S. Read, T. Christoph, K. Rutten, 2014, European journal of pain.

Mu-opioid peptide (MOP) and nociceptin/orphanin FQ peptide (NOP) receptor activation both contribute to the discriminative stimulus properties of cebranopadol in the rat

T. Tzschentke, K. Rutten, 2018, Neuropharmacology.

Analysis of spatial orientation strategies of male and female Wistar rats in a Morris water escape task

A. Blokland, J. Prickaerts, K. Rutten, 2006, Behavioural Brain Research.