D. Kambe

发表

Efficacy of a glycine transporter 1 inhibitor TASP0315003 in animal models of cognitive dysfunction and negative symptoms of schizophrenia

S. Chaki, S. Okuyama, T. Okubo, 2015, Psychopharmacology.

Discovery of ORN0829, a potent dual orexin 1/2 receptor antagonist for the treatment of insomnia.

H. Kawamoto, N. Hino, Takeshi Aoki, 2020, Bioorganic & medicinal chemistry.

Discovery and in vitro and in vivo profiles of N-ethyl-N-[2-[3-(5-fluoro-2-pyridinyl)-1H-pyrazol-1-yl]ethyl]-2-(2H-1,2,3-triazol-2-yl)-benzamide as a novel class of dual orexin receptor antagonist.

S. Tokura, H. Kawamoto, N. Ohtake, 2015, Bioorganic & medicinal chemistry.

Identification of 1-Methyl-N-(propan-2-yl)-N-({2-[4-(trifluoromethoxy)phenyl]pyridin-4-yl}methyl)-1H-imidazole-4-carboxamide as a Potent and Orally Available Glycine Transporter 1 Inhibitor.

M. Moriya, H. Ohta, Y. Kawakita, 2016, Chemical & pharmaceutical bulletin.

Efficacy of a glycine transporter 1 inhibitor TASP0315003 in animal models of cognitive dysfunction and negative symptoms of schizophrenia

S. Chaki, S. Okuyama, T. Okubo, 2015, Psychopharmacology.

Effects of a glycine transporter-1 inhibitor and D-serine on MK-801-induced immobility in the forced swimming test in rats

S. Chaki, H. Koike, H. Hikichi, 2015, Behavioural Brain Research.

Differential effects of NMDA receptor antagonists at lower and higher doses on basal gamma band oscillation power in rat cortical electroencephalograms

S. Chaki, J. Karasawa, D. Kambe, 2014, Neuropharmacology.

Effects of TS-142, a novel dual orexin receptor antagonist, on sleep in patients with insomnia: a randomized, double-blind, placebo-controlled phase 2 study

M. Uchiyama, N. Uchimura, Yu Kajiyama, 2022, Psychopharmacology.

Effects of quercetin on the sleep–wake cycle in rats: Involvement of gamma-aminobutyric acid receptor type A in regulation of rapid eye movement sleep

S. Chaki, M. Yoshimoto, K. Honda, 2010, Brain Research.

AMPA receptor mediates mGlu 2/3 receptor antagonist-induced dopamine release in the rat nucleus accumbens shell

S. Chaki, J. Karasawa, D. Kambe, 2010, Neurochemistry International.

Residual effects of zopiclone on driving performance using a standardized driving simulator among healthy volunteers

M. Ando, K. Iwamoto, N. Ozaki, 2022, Psychopharmacology.

Development and validation of a driving simulator for evaluating the residual effects of drugs on driving performance – sensitivity analysis using zopiclone as a positive control

M. Ando, K. Iwamoto, N. Ozaki, 2020, Medicine.