R. Boyle

发表

Modulating Protein-Protein Interactions of the Mitotic Polo-like Kinases to Target Mutant KRAS

G. McKenzie, C. Torrance, A. Venkitaraman, 2017, Cell chemical biology.

The design of a new potent and selective ligand for the orphan bombesin receptor subtype 3 (BRS3)

K. Wada, T. Arai, E. Wada, 2005, Journal of peptide science : an official publication of the European Peptide Society.

Development of a Novel Cell-Permeable Protein–Protein Interaction Inhibitor for the Polo-box Domain of Polo-like Kinase 1

D. Spring, G. McKenzie, A. Venkitaraman, 2019, ACS omega.

Identification of inhibitors of protein kinase B using fragment-based lead discovery.

Marcel L Verdonk, Paul G Wyatt, Michelle D Garrett, 2007, Journal of medicinal chemistry.

CHK1 Inhibition Synergizes with Gemcitabine Initially by Destabilizing the DNA Replication Apparatus.

D. Jodrell, F. Richards, R. Boyce, 2015, Cancer research.

Targeting Translation Control with p70 S6 Kinase 1 Inhibitors to Reverse Phenotypes in Fragile X Syndrome Mice

E. Klann, A. Bhattacharya, Daniel G Smith, 2016, Neuropsychopharmacology.

Hypoxia: targeting the tumour.

R. Boyle, S. Travers, 2006, Anti-cancer agents in medicinal chemistry.

Rapid evolution of 6-phenylpurine inhibitors of protein kinase B through structure-based design.

Ian Collins, Michelle D Garrett, Valerio Berdini, 2007, Journal of medicinal chemistry.

Structure‐activity studies on prolactin‐releasing peptide (PrRP). Analogues of PrRP‐(19–31)‐peptide

J. Humphries, Robert Downham, T. Ganguly, 2005, Journal of peptide science : an official publication of the European Peptide Society.

TITLE: CHK1 inhibition synergizes with gemcitabine initially by destabilizing the DNA replication apparatus AUTHORS AND AFFILIATIONS:

D. Jodrell, R. Boyce, Francés, 2015 .

Preclinical validation of a novel compound targeting p70S6 kinase in breast cancer

G. Baldassarre, B. Belletti, S. Massarut, 2016, Aging.

A comparison of physicochemical property profiles of marketed oral drugs and orally bioavailable anti-cancer protein kinase inhibitors in clinical development.

M. Verdonk, A. Gill, Gill L. Adrian, 2007, Current topics in medicinal chemistry.