Jamie Young

发表

Dissecting mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage

S. Nik-Zainal, A. Degasperi, J. Choudhary, 2020, bioRxiv.

A practical framework and online tool for mutational signature analyses show intertissue variation and driver dependencies

S. Morganella, H. Davies, S. Nik-Zainal, 2020, Nature Cancer.

Substitution mutational signatures in whole-genome–sequenced cancers in the UK population

S. Nik-Zainal, H. Davies, A. Degasperi, 2022, Science.

Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists

U. McDermott, S. Barthorpe, S. Price, 2022, Molecular cancer therapeutics.

A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage

Katherine R. Smith, M. B. Pereira, A. Need, 2021, Nature Cancer.

Author Correction: A practical framework and online tool for mutational signature analyses show intertissue variation and driver dependencies

Andrea Degasperi, Sandro Morganella, Xueqing Zou, 2020, Nature Cancer.

Insights from multi-omic modeling of neurodegeneration in xeroderma pigmentosum using an induced pluripotent stem cell system.

S. Nik-Zainal, A. Degasperi, H. Fassihi, 2024, Cell reports.

A rare genetic disorder provides insights into mechanisms of early-onset neurodegeneration

C. Bakal, S. Nik-Zainal, A. Degasperi, 2023, medRxiv.