J. Trudeau

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Increased TGF-β2 in severe asthma with eosinophilia

S. Wenzel, S. Balzar, M. Strand, 2005 .

Increased TGF-beta2 in severe asthma with eosinophilia.

S. Wenzel, S. Balzar, M. Strand, 2005, The Journal of allergy and clinical immunology.

Persistent wheezing in very young children is associated with lower respiratory inflammation.

S. Wenzel, S. Balzar, J. Westcott, 2001, American journal of respiratory and critical care medicine.

PEBP1 acts as a rheostat between prosurvival autophagy and ferroptotic death in asthmatic epithelial cells

Simon C Watkins, I. Bahar, H. Bayır, 2020, Proceedings of the National Academy of Sciences.

Effect of 5-lipoxygenase inhibition on bronchoconstriction and airway inflammation in nocturnal asthma.

S. Wenzel, R. Martin, J. Westcott, 1995, American journal of respiratory and critical care medicine.

Peritoneal lavage fluid alters patterns of eicosanoid production in murine bone marrow-derived and peritoneal macrophages: Dependency on inflammatory state of the peritoneum

S. Wenzel, D. Riches, J. Westcott, 1993, Inflammation.

BAL Cell Gene Expression in Severe Asthma Reveals Mechanisms of Severe Disease and In ﬂ uences of Medications

W. Busse, E. Bleecker, J. Tedrow, 2019 .

IL-27 and Type-2 immunity in asthma: Association with severity, CXCL9 and STAT signaling

S. Wenzel, Haizhen Hu, A. Ray, 2015 .

Dysfunctional ErbB2, an EGF receptor family member, in asthmatic airway epithelial cells critically hinders repair after mechanical wounding

B. Modena, S. Wenzel, Xiu-xia Zhou, 2019 .

Neutrophil-derived matrix metalloproteinase-9 is increased in severe asthma and poorly inhibited by glucocorticoids.

S. Wenzel, Yongchang Sun, M. Cundall, 2003, The Journal of allergy and clinical immunology.

Nasal polyps 15-lipoxygenase 1 promotes CCL26/Eotaxin3 expression through ERK activation.

S. Wenzel, Xiu-xia Zhou, Zheng Liu, 2019, The Journal of allergy and clinical immunology.

Distinguishing asthma phenotypes: Role of age of onset and eosinophilic inflammation

S. Wenzel, S. Balzar, Ashley Busacker, 2004 .

Selective downregulation of prostaglandin E2-related pathways by the Th2 cytokine IL-13.

S. Wenzel, Haizhen Hu, J. Westcott, 2006, The Journal of allergy and clinical immunology.

Nasal polyps 15-lipoxygenase 1 promotes CCL26/Eotaxin3 expression through ERK activation.

S. Wenzel, Xiu-xia Zhou, Zheng Liu, 2019, The Journal of allergy and clinical immunology.

MAPK Regulation of IL-4/IL-13 Receptors Contributes to the Synergistic Increase in CCL11/Eotaxin-1 in Response to TGF-β1 and IL-13 in Human Airway Fibroblasts

S. Wenzel, Xiu-xia Zhou, Haizhen Hu, 2012, The Journal of Immunology.

Peripheral blood and airway tissue expression of transforming growth factor beta by neutrophils in asthmatic subjects and normal control subjects.

S. Wenzel, S. Balzar, H. Chu, 2000, The Journal of allergy and clinical immunology.

Theophylline: potential antiinflammatory effects in nocturnal asthma.

S. Wenzel, R. Martin, M. Kraft, 1996, The Journal of allergy and clinical immunology.

Baseline sputum eosinophil+neutrophil subgroups' clinical characteristics and longitudinal trajectories for NHLBI Severe Asthma Research Program (SARP 3) Cohort.

E. Bleecker, Allison Crosby-Thompson, E. Israel, 2020, The Journal of allergy and clinical immunology.

Mechanisms of allergy Peripheral blood and airway tissue expression of transforming growth factor β by neutrophils in asthmatic subjects and normal control subjects

S. Wenzel, S. Balzar, H. Chu, 2000 .

Fibroblasts Eotaxin-1 Production in Human Airway and IL-13 Synergistically Increase β TGF-Hong

S. Wenzel, Wei Zhou, J. Westcott, 2002 .

Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics.

S. Wenzel, H. Chu, L. Schwartz, 1999, American journal of respiratory and critical care medicine.

Transforming growth factor-beta2 induces bronchial epithelial mucin expression in asthma.

S. Wenzel, S. Balzar, J. Westcott, 2004, The American journal of pathology.

Expression and activation of 15‐lipoxygenase pathway in severe asthma: relationship to eosinophilic phenotype and collagen deposition

S. Wenzel, S. Balzar, J. Westcott, 2002, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Nitric oxide and related enzymes in asthma: relation to severity, enzyme function and inflammation

S. Wenzel, K. Chibana, Y. Tochino, 2012, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

IL-27 and type 2 immunity in asthmatic patients: association with severity, CXCL9, and signal transducer and activator of transcription signaling.

S. Wenzel, Haizhen Hu, A. Ray, 2015, The Journal of allergy and clinical immunology.

15-Lipoxygenase 1 interacts with phosphatidylethanolamine-binding protein to regulate MAPK signaling in human airway epithelial cells

Valerie B O'Donnell, Claudette M St Croix, Sally E Wenzel, 2011, Proceedings of the National Academy of Sciences.

Epithelial eotaxin-2 and eotaxin-3 expression: relation to asthma severity, luminal eosinophilia and age at onset

S. Wenzel, A. Ray, P. Ray, 2012, Thorax.

High IFN-g and low SLPI mark severe asthma in mice and humans

S. Wenzel, J. Milošević, A. Ray, 2019 .

Reduced L-Arginine/ADMA As A Potential Mechanism To Explain Increased Symptom Severity And Reduced Atopy In Late Onset Obese Asthmatics

S. Wenzel, F. Holguin, R. Powers, 2012, ATS 2012.

Bronchoalveolar Lavage Cell Gene Expression in Severe Asthma Reveals Mechanisms of Severe Disease and Influences of Medications.

W. Busse, E. Bleecker, J. Tedrow, 2019, American journal of respiratory and critical care medicine.

Dysfunctional ErbB2, an EGF receptor family member, hinders repair of airway epithelial cells from asthmatic patients.

B. Modena, S. Wenzel, Xiu-xia Zhou, 2019, The Journal of allergy and clinical immunology.

Prostaglandin D₂ pathway upregulation: relation to asthma severity, control, and TH2 inflammation.

Stacy L. Gelhaus, S. Wenzel, B. Freeman, 2013, The Journal of allergy and clinical immunology.

High IFN-γ and low SLPI mark severe asthma in mice and humans.

S. Wenzel, J. Milošević, A. Ray, 2015, The Journal of clinical investigation.

High-dimensional profiling clusters asthma severity by lymphoid and non-lymphoid status

N. Aghaeepour, K. Nadeau, S. Wenzel, 2021, Cell reports.

The Complex Relationship Between Inflammation And Lung Function In Severe Asthma

J. Alcorn, S. Wenzel, M. Manni, 2014, Mucosal Immunology.

IL‐4 Induces IL17Rb Gene Transcription in Monocytic Cells with Coordinate Autocrine IL‐25 Signaling

S. Wenzel, M. Rojas, R. Mallampalli, 2017, American journal of respiratory cell and molecular biology.

CERAMIDE IN APOPTOSIS AND OXIDATIVE STRESS IN ALLERGIC INFLAMMATION AND ASTHMA.

S. Milstien, S. Spiegel, S. Wenzel, 2020, The Journal of allergy and clinical immunology.

Distinguishing severe asthma phenotypes: role of age at onset and eosinophilic inflammation.

S. Wenzel, S. Balzar, Ashley Busacker, 2004, The Journal of allergy and clinical immunology.

Brain-Derived Neurotrophic Factor Expression in Asthma. Association with Severity and Type 2 Inflammatory Processes.

S. Wenzel, Xiu-xia Zhou, Haizhen Hu, 2015, American journal of respiratory cell and molecular biology.

Interleukin-13 augments transforming growth factor-beta1-induced tissue inhibitor of metalloproteinase-1 expression in primary human airway fibroblasts.

S. Wenzel, Xiu-xia Zhou, J. Lundin, 2005, American journal of physiology. Cell physiology.

Sialylation of MUC4β N-glycans by ST6GAL1 orchestrates human airway epithelial cell differentiation associated with type-2 inflammation.

E. Bleecker, B. Modena, N. Kaminski, 2019, JCI insight.

IL‐13 induced increases in nitrite levels are primarily driven by increases in inducible nitric oxide synthase as compared with effects on arginases in human primary bronchial epithelial cells

S. Wenzel, Haizhen Hu, S. Balzar, 2008, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

15LO1 dictates glutathione redox changes in asthmatic airway epithelium to worsen type 2 inflammation

S. Wenzel, A. Ray, P. Woodruff, 2021, The Journal of clinical investigation.

Regional fibroblast heterogeneity in the lung: implications for remodeling.

S. Wenzel, Xiu-xia Zhou, Haizhen Hu, 2006, American journal of respiratory and critical care medicine.

Interleukin-13-induced MUC5AC is regulated by 15-lipoxygenase 1 pathway in human bronchial epithelial cells.

S. Wenzel, Haizhen Hu, S. Balzar, 2009, American journal of respiratory and critical care medicine.

Mechanisms of tissue inhibitor of metalloproteinase 1 augmentation by IL-13 on TGF-beta 1-stimulated primary human fibroblasts.

S. Wenzel, Xiu-xia Zhou, Haizhen Hu, 2007, The Journal of allergy and clinical immunology.

The relationship of induced-sputum inflammatory cells to BAL and biopsy.

P. Silkoff, J. Trudeau, S. Wenzel, 2003, Chest.

TGF-β and IL-13 Synergistically Increase Eotaxin-1 Production in Human Airway Fibroblasts1

S. Wenzel, Xiu-xia Zhou, J. Westcott, 2002, The Journal of Immunology.

IL-13 desensitizes β2-adrenergic receptors in human airway epithelial cells through a 15-lipoxygenase/G protein receptor kinase 2 mechanism.

S. Wenzel, Haizhen Hu, M. Profita, 2015, The Journal of allergy and clinical immunology.

Transforming growth factor-beta2 induces bronchial epithelial mucin expression in asthma.

S. Wenzel, S. Balzar, J. Westcott, 2004, The American journal of pathology.

An Airway Epithelial iNOS-DUOX2-Thyroid Peroxidase Metabolome Drives Th1/Th2 Nitrative Stress in Human Severe Asthma

M. Gladwin, W. Busse, J. Tedrow, 2014, Mucosal Immunology.

Single oral dose of prednisone decreases leukotriene B4 production by alveolar macrophages from patients with nocturnal asthma but not control subjects: relationship to changes in cellular influx and FEV1.

W. R. Beam, S. Wenzel, R. Martin, 1994, The Journal of allergy and clinical immunology.

Sialylation of MUC4β N-glycans by ST6GAL1 orchestrates human airway epithelial cell differentiation associated with type-2 inflammation.

E. Bleecker, B. Modena, N. Kaminski, 2019, JCI insight.

Brain-Derived Neurotrophic Factor Expression in Asthma. Association with Severity and Type 2 Inflammatory Processes.

S. Wenzel, Xiu-xia Zhou, Haizhen Hu, 2015, American journal of respiratory cell and molecular biology.

Compartmentalized mitochondrial ferroptosis converges with optineurin-mediated mitophagy to impact airway epithelial cell phenotypes and asthma outcomes

Y. Tyurina, V. Tyurin, A. Kapralov, 2024, Nature communications.