R. Dodd

发表

Mitochondrial Protein Lipoylation and the 2-Oxoglutarate Dehydrogenase Complex Controls HIF1α Stability in Aerobic Conditions

G. Dougan, P. Lehner, Ana S. H. Costa, 2016, Cell metabolism.

Lysine‐63‐linked ubiquitination is required for endolysosomal degradation of class I molecules

P. Lehner, M. Saville, J. Luzio, 2006, The EMBO journal.

Downregulation of cell surface receptors by the K3 family of viral and cellular ubiquitin E3 ligases

P. Lehner, Simon Hoer, Lidia M. Duncan, 2005, Immunological reviews.

Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, while the Alzheimer’s R47H mutant does the opposite

D. Klenerman, P. S. St George-Hyslop, P. Fraser, 2020, bioRxiv.

Structural biology of presenilin 1 complexes

P. S. St George-Hyslop, P. Fraser, Fusheng Chen, 2014, Molecular Neurodegeneration.

C-Type lectin-like domains in Caenorhabditis elegans: predictions from the complete genome sequence.

K. Drickamer, R. Dodd, 1999, Glycobiology.

Therapeutic Monoclonal Antibodies to Complex Membrane Protein Targets: Antigen Generation and Antibody Discovery Strategies

T. Wilkinson, D. Schofield, R. Dodd, 2018, BioDrugs.

Lectin-like proteins in model organisms: implications for evolution of carbohydrate-binding activity.

K. Drickamer, K Drickamer, R B Dodd, 2001, Glycobiology.

Generating therapeutic monoclonal antibodies to complex multi-spanning membrane targets: Overcoming the antigen challenge and enabling discovery strategies.

T. Wilkinson, D. Schofield, R. Dodd, 2020, Methods.

Solution Structure of the Kaposi's Sarcoma-associated Herpesvirus K3 N-terminal Domain Reveals a Novel E2-binding C4HC3-type RING Domain*

M. Bycroft, R. Read, P. Lehner, 2004, Journal of Biological Chemistry.

Interaction of Mannose-binding Protein with Associated Serine Proteases

R. Wallis, R. Dodd, 2000, The Journal of Biological Chemistry.

Current and future implications of basic and translational research on amyloid-β peptide production and removal pathways

P. S. St George-Hyslop, P. Fraser, J. Sévalle, 2015, Molecular and Cellular Neuroscience.

Structural biology of presenilin 1 complexes

P. S. St George-Hyslop, P. Fraser, Fusheng Chen, 2014, Molecular Neurodegeneration.

Structural Interactions between Inhibitor and Substrate Docking Sites Give Insight into Mechanisms of Human PS1 Complexes

B. Hyman, P. S. St George-Hyslop, L. Farrer, 2014, Structure.

TREM2 shedding by cleavage at the H157‐S158 bond is accelerated for the Alzheimer's disease‐associated H157Y variant

P. S. St George-Hyslop, I. Chessell, J. Sévalle, 2017, EMBO molecular medicine.

TREM 2 shedding by cleavage at the H 157 -S 158 bond is accelerated for the Alzheimer ’ s disease-associated H 157 Y variant

I. Chessell, P. George-Hyslop, J. Sévalle, 2017 .

ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function

Claire H. Michel, C. Holt, E. Rees, 2015, Neuron.

Oxidised IL-33 signals via RAGE/EGFR to drive a COPD-associated phenotype

G. Sims, E. S. Cohen, D. G. Rees, 2022, 03.02 - Airway cell biology and immunopathology.

Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation

D. Klenerman, P. S. St George-Hyslop, P. Fraser, 2021, The Journal of biological chemistry.

An exTREMe disruption in Alzheimer's cleanup

R. Dodd, 2018, The Journal of Biological Chemistry.

Mechanism of farnesylated CAAX protein processing by the integral membrane protease Rce1

D. Barford, S. Iwata, I. Manolaridis, 2013, Nature.

Vigilin interacts with signal peptide peptidase

P. Fraser, P. George-Hyslop, Fusheng Chen, 2012, Proteome Science.

Therapeutic Monoclonal Antibodies to Complex Membrane Protein Targets: Antigen Generation and Antibody Discovery Strategies

T. Wilkinson, D. Schofield, R. Dodd, 2018, BioDrugs.

Mechanism of isoprenylcysteine carboxyl methylation from the crystal structure of the integral membrane methyltransferase ICMT.

D. Barford, I. Manolaridis, Ziguo Zhang, 2011, Molecular cell.

Mitochondrial Protein Lipoylation and the 2-Oxoglutarate Dehydrogenase Complex Controls HIF1α Stability in Aerobic Conditions

G. Dougan, P. Lehner, Ana S. H. Costa, 2016, Cell metabolism.

Oxidised IL-33 drives COPD epithelial pathogenesis via ST2-independent RAGE/EGFR signalling complex

J. Erjefält, G. Sims, E. S. Cohen, 2023, European Respiratory Journal.

Mechanism of isoprenylcysteine carboxyl methylation from the crystal structure of the integral membrane methyltransferase ICMT.

D. Barford, I. Manolaridis, Ziguo Zhang, 2011, Molecular cell.