J. Timm

发表

Resolving the Dynamic Motions of SARS-CoV-2 nsp7 and nsp8 Proteins Using Structural Proteomics

E. Arnold, P. Griffin, R. Yadav, 2021, bioRxiv.

Biochemical and structural insights into SARS-CoV-2 polyprotein processing by Mpro

S. Sarafianos, E. Arnold, P. Griffin, 2022, bioRxiv.

Drug Design Strategies to Avoid Resistance in Direct-Acting Antivirals and Beyond.

C. Schiffer, E. Nalivaika, Akbar Ali, 2021, Chemical reviews.

Deciphering the Molecular Mechanism of HCV Protease Inhibitor Fluorination as a General Approach to Avoid Drug Resistance.

C. Schiffer, Akbar Ali, Adam K. Hedger, 2022, Journal of molecular biology.

Deciphering the Molecular Mechanism of HCV Protease Inhibitor Fluorination as a General Approach to Avoid Drug Resistance

C. Schiffer, E. Chan, Akbar Ali, 2021, bioRxiv.

Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors

C. Schiffer, Akbar Ali, Adam K. Hedger, 2020, mBio.

Molecular and structural mechanism of pan-genotypic HCV NS3/4A protease inhibition by glecaprevir [preprint]

C. Schiffer, Akbar Ali, M. Henes, 2020 .

Molecular and structural mechanism of pan-genotypic HCV NS3/4A protease inhibition by glecaprevir

C. Schiffer, Akbar Ali, Nese Kurt-Yilmaz, 2019, bioRxiv.

Cell cycle regulation and novel structural features of thymidine kinase, an essential enzyme in Trypanosoma brucei

L. Bird, K. Wilson, J. Nettleship, 2016, Molecular microbiology.

Structural and Kinetic Characterization of Thymidine Kinase from Leishmania major

K. Wilson, J. Nettleship, D. González-Pacanowska, 2015, PLoS neglected tropical diseases.

Insights into the molecular architecture and histone H3-H4 deposition mechanism of yeast Chromatin assembly factor 1

J. Langowski, F. Ochsenbein, G. Almouzni, 2017, eLife.

Structural Characterization of Acidic M17 Leucine Aminopeptidases from the TriTryps and Evaluation of Their Role in Nutrient Starvation in Trypanosoma brucei

K. Wilson, D. González-Pacanowska, M. Valente, 2017, mSphere.

Structure and promoter activity of the mouse CDC25A gene

C. Johnston, P. Epstein, M. Paskind, 2000, Mammalian Genome.

Structures of adenosine kinase from Trypanosoma brucei brucei.

K. Wilson, D. González-Pacanowska, J. Timm, 2014, Acta crystallographica. Section F, Structural biology communications.

Tying down the arm in Bacillus dUTPase: structure and mechanism.

K. Wilson, J. García-Nafría, J. Turkenburg, 2013, Acta crystallographica. Section D, Biological crystallography.

Design of a minimal di-nickel hydrogenase peptide

Joshua A. Mancini, Kate M. Waldie, P. Falkowski, 2022, bioRxiv.

Pan-3C Protease Inhibitor Rupintrivir Binds SARS-CoV-2 Main Protease in a Unique Binding Mode

C. Schiffer, J. Lee, E. Nalivaika, 2021, Biochemistry.

The carbon monoxide dehydrogenase accessory protein CooJ is a histidine-rich multidomain dimer containing an unexpected Ni(II)-binding site

S. Ciurli, P. Carpentier, B. Zambelli, 2019, The Journal of Biological Chemistry.

The CO dehydrogenase accessory protein CooT is a novel nickel-binding protein.

S. Ciurli, C. Brochier-Armanet, B. Zambelli, 2017, Metallomics : integrated biometal science.

Molecular and structural mechanism of pan-genotypic HCV NS3/ Molecular and structural mechanism of pan-genotypic HCV NS3/ 4A protease inhibition by glecaprevir [preprint] 4A protease inhibition by glecaprevir [preprint] us you.

C. Schiffer, Akbar Ali, M. Henes, 2022 .

Cell cycle regulation and novel structural features of thymidine kinase, an essential enzyme in Trypanosoma brucei

L. Bird, K. Wilson, J. Nettleship, 2016, Molecular microbiology.

Structures of adenosine kinase from Trypanosoma brucei brucei.

K. Wilson, D. González-Pacanowska, J. Timm, 2014, Acta crystallographica. Section F, Structural biology communications.

Acidic and Evaluation

K. Wilson, D. González-Pacanowska, M. Valente, 2018 .