J. Recio

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Genetic profile of GNAQ-mutated blue melanocytic neoplasms reveals mutations in genes linked to genomic instability and the PI3K pathway

A. Vivancos, J. Hernández-Losa, J. Cortés, 2016, Oncotarget.

ALDH1A3 is epigenetically regulated during melanocyte transformation and is a target for melanoma treatment

S. Tenbaum, J. Hernández-Losa, G. Fournet, 2017, Oncogene.

Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis

R. DePinho, R. Sharp, G. Merlino, 2003, Nature Medicine.

E1a Gene Expression Blocks the ERK1/2 Signaling Pathway by Promoting Nuclear Localization and MKP Up-regulation

S. Y. Cajal, N. Martínez, J. Rojas, 2008, Journal of Biological Chemistry.

Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis

R. DePinho, R. Sharp, G. Merlino, 2002, Nature Medicine.

Ink4a/arf deficiency promotes ultraviolet radiation-induced melanomagenesis.

R. DePinho, P. Duray, G. Merlino, 2002, Cancer research.

Erratum: Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis (Nature Medicine (2002) 8 (1276-1280))

R. DePinho, R. Sharp, G. Merlino, 2003 .

Ink 4 a / Arf Deficiency Promotes Ultraviolet Radiation-induced Melanomagenesis 1

R. DePinho, P. Duray, G. Merlino, 2002 .

Uncoupling of the LKB1-AMPKα Energy Sensor Pathway by Growth Factors and Oncogenic BRAFV600E

G. Merlino, F. Canals, N. Colomé, 2009, PloS one.

Genetic Profiles of Squamous Cell Carcinomas Associated with Recessive Dystrophic Epidermolysis Bullosa Unveil NOTCH and TP53 Mutations and an Increased MYC Expression.

F. Mancuso, A. Vivancos, J. Hernández-Losa, 2017, The Journal of investigative dermatology.

Both normal and transforming PCPH proteins have guanosine diphosphatase activity but only the oncoprotein cooperates with Ras in activating extracellular signal-regulated kinase ERK1.

B. Maskeri, V. Notario, J. Velasco, 2000, Cancer research.

Signal-regulated Kinase ERK 1 Cooperates with Ras in Activating Extracellular Guanosine Diphosphatase Activity But Only the Oncoprotein Both Normal and Transforming PCPH Proteins Have

B. Maskeri, V. Notario, J. Velasco, 2000 .

Up-Regulation of CD 44 v 6 in Melanoma Cells through Egr-1 Hepatocyte Growth Factor / Scatter Factor Induces Feedback

G. Merlino, J. Recio, 2003 .

BRAF activation by metabolic stress promotes glycolysis sensitizing NRASQ61-mutated melanomas to targeted therapy

R. Bartrons, J. Hernández-Losa, A. Manzano, 2022, Nature Communications.

Partial depletion of intracellular ATP mediates the stress-survival function of the PCPH oncoprotein.

V. Notario, T. Kawakami, J. Paez, 2002, Cancer research.

Dynamics of clinical biomarkers as predictors of immunotherapy benefit in metastatic melanoma patients

D. Bodet, V. García-Patos, E. Muñoz-Couselo, 2020, Clinical and Translational Oncology.

TET2 controls chemoresistant slow-cycling cancer cell survival and tumor recurrence

J. Tabernero, P. Nuciforo, R. Dienstmann, 2018, The Journal of clinical investigation.

Neonatal sunburn and melanoma in mice

P. Duray, G. Merlino, F. Noonan, 2001, Nature.

Hepatocyte growth factor/scatter factor activates proliferation in melanoma cells through p38 MAPK, ATF-2 and cyclin D1

G. Merlino, J. Recio, 2002, Oncogene.

Association of JAK/STAT genetic variants with cutaneous melanoma

C. Torricelli, L. O. Coser, C. Lima, 2022, Frontiers in Oncology.

Lkb1 Loss Promotes Tumor Progression of BRAFV600E-Induced Lung Adenomas

M. Barbacid, J. Flores, J. Martı́n-Caballero, 2013, PloS one.

Methylthioadenosine (MTA) inhibits melanoma cell proliferation and in vivo tumor growth

J. Hernández-Losa, T. Moliné, A. Pujol, 2010, BMC Cancer.

The dual PI3K/mTOR inhibitor PI‐103 promotes immunosuppression, in vivo tumor growth and increases survival of sorafenib‐treated melanoma cells

Rosa Gil, J. Hernández-Losa, T. Moliné, 2010, International journal of cancer.

STK11 (LKB1) missense somatic mutant isoforms promote tumor growth, motility and inflammation

J. Villanueva, R. Selgas, J. Lizcano, 2020, Communications Biology.

A Mouse Model Uncovers LKB1 as an UVB-Induced DNA Damage Sensor Mediating CDKN1A (p21WAF1/CIP1) Degradation

J. Flores, J. Martı́n-Caballero, A. Vivancos, 2014, PLoS genetics.

Hepatocyte growth factor/scatter factor induces feedback up-regulation of CD44v6 in melanoma cells through Egr-1.

G. Merlino, J. Recio, 2003, Cancer research.

New approach to cancer therapy based on a molecularly defined cancer classification

J. Seoane, A. Vivancos, J. Cortés, 2014, CA: a cancer journal for clinicians.

Genetic evolution of nevus of Ota reveals clonal heterogeneity acquiring BAP1 and TP53 mutations

A. Vivancos, J. Hernández-Losa, D. Bodet, 2016, Pigment cell & melanoma research.

Combination therapy with vemurafenib (PLX4032/RG7204) and metformin in melanoma cell lines with distinct driver mutations

P. Mischel, A. Ribas, R. Lo, 2011, Journal of Translational Medicine.

Title Combination therapy with vemurafenib ( PLX 4032 / RG 7204 ) and metformin in melanoma cell lines with distinct driver mutations

P. Mischel, A. Ribas, R. Lo, 2011 .

cDNA isolation, expression, and chromosomal localization of the mouse Pcph proto‐oncogene

C. Powers, N. Zambrano, V. Notario, 1999, Molecular carcinogenesis.

Activation of the HIV-1 Long Terminal Repeat by Nerve Growth Factor*

A. Aranda, J. Recio, 1997, The Journal of Biological Chemistry.

Protein Arginine Methyltransferase 5 Regulates ERK1/2 Signal Transduction Amplitude and Cell Fate Through CRAF

G. Merlino, S. Tenbaum, M. Ávila, 2011, Science Signaling.

Retinoic acid stimulates HIV‐1 transcription in human neuroblastoma SH‐SY5Y cells

A. Aranda, J. Martín-Nieto, J. Recio, 2000, FEBS letters.

Early evolutionary divergence between papillary and anaplastic thyroid cancers

J. Tabernero, P. Nuciforo, J. Tabernero, 2018, Annals of oncology : official journal of the European Society for Medical Oncology.

Oral Methylthioadenosine Administration Attenuates Fibrosis and Chronic Liver Disease Progression in Mdr2−/− Mice

R. Urtasun, J. Prieto, F. Corrales, 2010, PloS one.

Epidermal Growth Factor Receptor Signaling in Hepatocellular Carcinoma: Inflammatory Activation and a New Intracellular Regulatory Mechanism

R. Urtasun, J. Prieto, F. Corrales, 2012, Digestive Diseases.

Early evolutionary divergence between papillary and anaplastic thyroid cancers.

P. Nuciforo, J. Tabernero, J. Seoane, 2019, Annals of Oncology.

Expression of the Protein Product of the PCPH Proto-oncogene in Human Tumor Cell Lines

V. Notario, A. Rouzaut, J. Recio, 2001, Radiation research.

Influence of Ras and retinoic acid on nerve growth factor induction of transin gene expression in PC12 cells

A. Aranda, J. Cosgaya, J. Recio, 1997, Oncogene.