C. Hesslinger

发表

Association of Circulating Proteins with Death or Lung Transplant in Patients with Idiopathic Pulmonary Fibrosis in the IPF-PRO Registry Cohort

I. Noth, K. Flaherty, J. Lasky, 2022, Lung.

Trial of a Preferential Phosphodiesterase 4B Inhibitor for Idiopathic Pulmonary Fibrosis.

L. Richeldi, V. Cottin, M. Wijsenbeek, 2022, The New England journal of medicine.

BYK 191023 ( 2-[ 2-( 4-Methoxy-pyridin-2-yl )-ethyl ]-3 H-imidazo [ 4 , 5b ] pyridine ) Is an NADPH-and Time-Dependent Irreversible Inhibitor of Inducible Nitric-Oxide Synthase

D. Stuehr, Mauro Tiso, R. Boer, 2008 .

BYK191023 (2-[2-(4-Methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine) Is an NADPH- and Time-Dependent Irreversible Inhibitor of Inducible Nitric-Oxide Synthase

D. Stuehr, Mauro Tiso, R. Boer, 2008, Molecular Pharmacology.

BYK191023 Is A NADPH- And Time-Dependent Irreversible Inhibitor Of Inducible Nitric-Oxide Synthase

D. Stuehr, Mauro Tiso, R. Boer, 2007 .

The Pteridine Pathway in the Zebrafish, Danio Rerio: Development in Neural Crest-Derived Cells and Its Control by GTP Cyclohydrolase I

I. Pelletier, L. Bally-Cuif, I. Ziegler, 2002 .

Inhibition of inducible nitric oxide synthase in respiratory diseases.

M. Lehner, W. Ulrich, R. Boer, 2009, Biochemical Society transactions.

Tetrahydrobiopterin, a Critical Factor in the Production and Role of Nitric Oxide in Mast Cells*

M. Gilchrist, A. Befus, C. Hesslinger, 2003, Journal of Biological Chemistry.

BI 1015550 is a PDE4B Inhibitor and a Clinical Drug Candidate for the Oral Treatment of Idiopathic Pulmonary Fibrosis

L. Wollin, F. Herrmann, C. Hesslinger, 2022, Frontiers in Pharmacology.

Development of the Pteridine Pathway in the Zebrafish,Danio rerio*

I. Pelletier, I. Ziegler, P. Boyle, 2000, The Journal of Biological Chemistry.

Gene Transfer of Human Guanosine 5′-Triphosphate Cyclohydrolase I Restores Vascular Tetrahydrobiopterin Level and Endothelial Function in Low Renin Hypertension

G. Fink, I. Kovesdi, Alex F. Chen, 2003, Circulation.

Glial cell line‐derived neurotrophic factor up‐regulates GTP‐cyclohydrolase I activity and tetrahydrobiopterin levels in primary dopaminergic neurones

M. Ueffing, T. Gasser, M. Meyer, 2002, Journal of neurochemistry.

Evidence for histamine as a transmitter in rat carotid body sensor cells

C. Prinz, M. Gratzl, C. Hesslinger, 2004, Journal of neurochemistry.

In Vivo Characterization of the Novel Imidazopyridine BYK191023 [2-[2-(4-Methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine], a Potent and Highly Selective Inhibitor of Inducible Nitric-Oxide Synthase

R. Schermuly, M. Lehner, J. Barsig, 2006, Journal of Pharmacology and Experimental Therapeutics.

Novel nanomolar imidazo[4,5-b]pyridines as selective nitric oxide synthase (iNOS) inhibitors: SAR and structural insights.

K. Diederichs, U. Grädler, T. Fuchss, 2011, Bioorganic & medicinal chemistry letters.

PKC-mediated Regulation of GTP Cyclohydrolase I in Mast Cells and Renal Mesangial Cells

J. Pfeilschifter, J. Rivera, I. Ziegler, 2002 .

Phosphorylation of GTP Cyclohydrolase I and Modulation of Its Activity in Rodent Mast Cells

E. Kremmer, M. Ueffing, L. Hültner, 1998, The Journal of Biological Chemistry.

Tetrahydrobiopterin precursor sepiapterin provides protection against neurotoxicity of 1‐methyl‐4‐phenylpyridinium in nigral slice cultures

J. Zimmer, M. Meyer, J. Gramsbergen, 2003, Journal of neurochemistry.

Attenuation of IgE-receptor signalling in mast cells as a molecular basis for the antiallergic action of glucocorticoids

O. Kassel, A. Cato, C. Hesslinger, 2003 .

Circulating matrix metalloproteinases and tissue metalloproteinase inhibitors in patients with idiopathic pulmonary fibrosis in the multicenter IPF-PRO Registry cohort

Hyun J. Kim, I. Noth, M. Strek, 2020, BMC Pulmonary Medicine.

Novel keto acid formate‐lyase and propionate kinase enzymes are components of an anaerobic pathway in Escherichia coli that degrades L‐threonine to propionate

G. Sawers, S. Fairhurst, C. Hesslinger, 1998, Molecular microbiology.

Regulation of GTP Cyclohydrolase I by Estrogen

A. Hingorani, P. Vallance, A. Ahluwalia, 2002 .

The tdcE gene in Escherichia coli strain W3110 is separated from the rest of the tdc operon by insertion of IS5 elements.

G. Sawers, C. Hesslinger, 1998, DNA sequence : the journal of DNA sequencing and mapping.

Peripheral blood proteomic profiling of idiopathic pulmonary fibrosis biomarkers in the multicentre IPF-PRO Registry

Hyun J. Kim, I. Noth, M. Strek, 2019, Respiratory Research.

The Glycyl Radical Enzyme TdcE Can Replace Pyruvate Formate-Lyase in Glucose Fermentation

G. Sawers, C. Hesslinger, N. Muller, 1998, Journal of bacteriology.

Additive effect of BI 1015550 and nintedanib in patients with IPF

L. Richeldi, S. Stowasser, D. Wachtlin, 2022, 12.01 - Idiopathic interstitial pneumonias.

The Novel Imidazopyridine 2-[2-(4-Methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine (BYK191023) Is a Highly Selective Inhibitor of the Inducible Nitric-Oxide Synthase

Susanne Strand, S. Strand, M. Lehner, 2006, Molecular Pharmacology.

The Novel Imidazopyridine BYK 191023 is a Highly Selective Inhibitor of the Inducible Nitric Oxide Synthase

S. Strand, M. Lehner, J. Strassner, 2005 .

Integrative multi-omics analysis reveals novel idiopathic pulmonary fibrosis endotypes associated with disease progression

I. Noth, M. Strek, R. Schmid, 2023, Respiratory Research.

Circulating metabolic profile in idiopathic pulmonary fibrosis: data from the IPF-PRO Registry

C. Newgard, T. Leonard, A. Namen, 2024, Respiratory research.

The Novel Imidazopyridine 2-[2-(4-Methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine (BYK191023) Is a Highly Selective Inhibitor of the Inducible Nitric-Oxide Synthase

S. Strand, M. Lehner, J. Strassner, 2006, Molecular Pharmacology.