Manbir Sandhu

发表

Variable G protein determinants of GPCR coupling selectivity

N. Vaidehi, N. Lambert, A. Inoue, 2019, Proceedings of the National Academy of Sciences.

Baclofen-associated neurophysiologic target engagement across species in fragile X syndrome

Lauren E. Ethridge, J. Sweeney, L. Schmitt, 2021, Journal of Neurodevelopmental Disorders.

T. Casale, Manbir Sandhu, 2010, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Effects of Rosiglitazone on Airway Hyperresponsiveness and Obstruction in Asthma

T. Casale, T. Wichman, V. Dimov, 2010 .

The use of the peroxisome proliferator-activated receptors γ agonist rosiglitazone to treat airway hyperreactivity.

T. Casale, R. Walters, T. Wichman, 2012, Annals of Allergy, Asthma & Immunology.

CEREBRAL VENOUS SINUS THROMBOSIS MANIFESTING AS A SPONTANEOUS LEFT TENTORIAL SUBDURAL HEMATOMA: A CASE REPORT

S. Hurley, Manbir Sandhu, J. Diego Lozano, 2022, Interdisciplinary Neurosurgery.

Conformational plasticity of the intracellular cavity of GPCR−G-protein complexes leads to G-protein promiscuity and selectivity

N. Vaidehi, S. Sivaramakrishnan, Manbir Sandhu, 2019, Proceedings of the National Academy of Sciences.

Dynamic spatiotemporal determinants modulate GPCR:G protein coupling selectivity and promiscuity

David E. Gloriam, M. Babu, N. Vaidehi, 2022, Nature Communications.

Facial Recognition: Issues, Techniques and Applications

Gurpreet Kaur, Manbir Sandhu, Gurpreet Kaur, 2016 .

The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma

Shondra M. Pruett-Miller, Samuel W. Brady, M. Babu, 2021, Nature Communications.

C-NHEJ without indels is robust and requires synergistic function of distinct XLF domains

Jeremy M. Stark, N. Vaidehi, J. Stark, 2018, Nature Communications.

Distinct structural mechanisms determine substrate affinity and kinase activity of protein kinase Cα

Adrien B. Larsen, Abhinandan Jain, N. Vaidehi, 2017, The Journal of Biological Chemistry.

Structural Elements in the Gαs and Gαq C Termini That Mediate Selective G Protein-coupled Receptor (GPCR) Signaling*

N. Vaidehi, S. Sivaramakrishnan, Rabia U. Malik, 2016, The Journal of Biological Chemistry.

The role of HER2 and HER3 in HER2-amplified cancers beyond breast cancers

A. Olshen, M. Moasser, Debarko Banerji, 2021, Scientific Reports.

Targeting HER3 by interfering with its Sec61-mediated cotranslational insertion into the endoplasmic reticulum

Yazmin P. Carrasco, J. Taunton, M. Moasser, 2014, Oncogene.

A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation

M. Sander, A. Grapin-Botton, Janel L. Kopp, 2012, Development.

Decoupling substrate binding and kinase activity of PKCα 1 Distinct structural mechanisms determine substrate affinity and kinase activity of Protein Kinase C

Adrien B. Larsen, Abhinandan Jain, N. Vaidehi, 2017 .

C-NHEJ without indels is robust and requires synergistic function of distinct XLF domains

N. Vaidehi, J. Stark, Ragini Bhargava, 2018, Nature Communications.

Bitopic Inhibition of ATP and Substrate Binding in Ser/Thr Kinases through a Conserved Allosteric Mechanism.

N. Vaidehi, T. Devamani, S. Sivaramakrishnan, 2018, Biochemistry.

Recent breakthroughs in computational structural biology harnessing the power of sequences and structures.

M. Babu, Bálint Mészáros, Kalyan Immadisetty, 2023, Current opinion in structural biology.

How Does the Proliferating Cell Nuclear Antigen Modulate Binding Specificity to Multiple Partner Proteins?

N. Vaidehi, R. Hickey, L. Malkas, 2017, J. Chem. Inf. Model..

Structural determinants of selective GPCR signaling 1 Structural elements in the Gαs and Gαq C-termini that mediate selective GPCR signaling

N. Vaidehi, S. Sivaramakrishnan, Rabia U. Malik, 2016 .

Dissecting the allosteric networks governing agonist efficacy and potency in G protein-coupled receptors

M. Babu, B. Kobilka, M. Bouvier, 2021, bioRxiv.

The PDE10A Inhibitor TAK-063 Reverses Sound-Evoked EEG Abnormalities in a Mouse Model of Fragile X Syndrome

Mahindra T. Makhija, D. Binder, C. Jonak, 2021, Neurotherapeutics.

Conformational plasticity of the intracellular cavity of GPCR−G-protein complexes leads to G-protein promiscuity and selectivity

N. Vaidehi, S. Sivaramakrishnan, Manbir Sandhu, 2019, Proceedings of the National Academy of Sciences.

Abstract 2635: Targeting HER3 by interfering with its Sec61-mediated cotranslational insertion into the endoplasmic reticulum

Yazmin P. Carrasco, J. Taunton, M. Moasser, 2015 .

Bitopic Inhibition of ATP and Substrate Binding in Ser/Thr Kinases through a Conserved Allosteric Mechanism.

N. Vaidehi, T. Devamani, Lisa G. Lippert, 2018, Biochemistry.

Machine Learning for Prioritization of Thermostabilizing Mutations for G-protein Coupled Receptors

K. Fennell, N. Vaidehi, V. Shanmugasundaram, 2019, bioRxiv.