Pilar Manzano

发表

Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents

F. Gamarro, C. Caffrey, D. González-Pacanowska, 2019, PLoS neglected tropical diseases.

Identification and Characterization of Hundreds of Potent and Selective Inhibitors of Trypanosoma brucei Growth from a Kinase-Targeted Library Screening Campaign

Gonzalo Colmenarejo, William G. Devine, T. Geary, 2014, PLoS neglected tropical diseases.

Identification and development of a series of disubstituted piperazines for the treatment of Chagas disease.

Peter G. Dodd, Frederick R. C. Simeons, L. Stojanovski, 2022, European journal of medicinal chemistry.

Metal-catalyzed oxidation and epoxidation of α-hydroxy vinyl and dienyl sulfoxides

A. Viso, R. F. D. L. Pradilla, Milagros Lorenzo, 2006 .

Sulfoxide-controlled SN2′ displacements between cuprates and vinyl and alkynyl epoxy sulfoxides

A. Viso, R. F. D. L. Pradilla, S. Castro, 2004 .

Stereoselective nucleophilic epoxidation of hydroxy vinyl sulfoxide derivatives

A. Viso, Ana M. Rodríguez, M. Martínez-Ripoll, 1996 .

Establishment of a Structure–Activity Relationship of 1H-Imidazo[4,5-c]quinoline-Based Kinase Inhibitor NVP-BEZ235 as a Lead for African Sleeping Sickness

Terry K. Smith, M. Navarro, M. Pollastri, 2014, Journal of medicinal chemistry.

Stereoselective Nucleophilic Epoxidation of Vinyl Sulfoxides: A Novel Route to Enantiopure Sulfinyl Oxiranes(,)(1).

A. Viso, R. Fernández de la Pradilla, S. Castro, 1996, The Journal of organic chemistry.

Identification of “Preferred” Human Kinase Inhibitors for Sleeping Sickness Lead Discovery. Are Some Kinases Better than Others for Inhibitor Repurposing?

Ana Rodriguez, H. Xi, Gonzalo Colmenarejo, 2016, ACS infectious diseases.

New and unexpected developments of the carbanion-mediated sulfonate (sulfonamide) intramolecular cyclization reaction (CSIC reaction)

J. Marco, S. Ingate, Pilar Manzano, 1998 .

New and Unexpected Developments of the Carbanion‐Mediated Sulfonate (Sulfonamide) Intramolecular Cyclization Reaction (CSIC Reaction).

J. Macro, S. Ingate, Pilar Manzano, 1998 .

Lead Optimization of 3,5-Disubstituted-7-Azaindoles for the Treatment of Human African Trypanosomiasis.

F. Gamarro, C. Caffrey, D. Gonzalez Pacanowska, 2021, Journal of medicinal chemistry.

Selectivity and Physicochemical Optimization of Repurposed Pyrazolo[1,5-b]pyridazines for the Treatment of Human African Trypanosomiasis

F. Gamarro, C. Caffrey, D. Gonzalez Pacanowska, 2019, Journal of medicinal chemistry.

Importance of secondary screening with clinical isolates for anti-leishmania drug discovery

S. Rijal, G. De Muylder, J. Dujardin, 2018, Scientific Reports.

An Invitation to Open Innovation in Malaria Drug Discovery: 47 Quality Starting Points from the TCAMS.

José María Bueno, Esther Fernández, Simon J F Macdonald, 2011, ACS medicinal chemistry letters.

Potent antimalarial 4-pyridones with improved physico-chemical properties.

J. Vidal, J. Lavandera, E. Herreros, 2011, Bioorganic & medicinal chemistry letters.

Hit-to-lead optimization of benzoxazepinoindazoles as human African trypanosomiasis therapeutics.

F. Gamarro, C. Caffrey, Lori Ferrins, 2019, Journal of medicinal chemistry.

Medicinal Chemistry Optimization of a Diaminopurine Chemotype: Toward a Lead for Trypanosoma brucei Inhibitors.

Baljinder Singh, M. Navarro, M. Pollastri, 2020, Journal of medicinal chemistry.

Structure-Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma cruzi Proteasome Inhibitors

Peter G. Dodd, Frederick R. C. Simeons, L. Stojanovski, 2023, Journal of medicinal chemistry.