N. Hartmann

The functional consequences of sodium channel NaV1.8 in human left ventricular hypertrophy

G. Hasenfuss, L. Maier, N. Frey, 2018, ESC heart failure.

Enhanced cardiac TBC1D10C expression lowers heart rate and enhances exercise capacity and survival

T. Seidler, D. Liebetanz, G. Hasenfuss, 2016, Scientific Reports.

Different activation of MAPKs and Akt/GSK3β after preload vs. afterload elevation

G. Hasenfuss, K. Toischer, B. Mohamed, 2022, ESC heart failure.

Sex-dependent alterations of Ca2+ cycling in human cardiac hypertrophy and heart failure.

J. Gummert, G. Hasenfuss, L. Maier, 2016, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

Diastolic dysfunction and arrhythmias caused by overexpression of CaMKIIδC can be reversed by inhibition of late Na+ current

L. Maier, W. Zimmermann, S. Wagner, 2010, Basic Research in Cardiology.

Differential regulation of sodium channels as a novel proarrhythmic mechanism in the human failing heart

J. Gummert, G. Hasenfuss, L. Maier, 2018, Cardiovascular research.

Sarcoplasmic reticulum calcium leak contributes to arrhythmia but not to heart failure progression

S. Luther, T. Seidler, S. Lehnart, 2018, Science Translational Medicine.

Inhibition of CaMKII Attenuates Progressing Disruption of Ca(2+) Homeostasis Upon Left Ventricular Assist Device Implantation in Human Heart Failure.

J. Gummert, A. Haverich, J. Schmitto, 2016, Artificial organs.

Detrimental proarrhythmogenic interaction of Ca2+/calmodulin-dependent protein kinase II and NaV1.8 in heart failure

G. Hasenfuss, L. Maier, K. Toischer, 2021, Nature Communications.

Enhanced late INa induces proarrhythmogenic SR Ca leak in a CaMKII-dependent manner.

A. Shah, L. Maier, C. Sag, 2014, Journal of molecular and cellular cardiology.

Electrophysiological and calcium-handling development during long-term culture of human-induced pluripotent stem cell-derived cardiomyocytes

F. Mason, Markus Rapedius, J. Heijman, 2023, Basic Research in Cardiology.

Late INa increases diastolic SR-Ca2+-leak in atrial myocardium by activating PKA and CaMKII

F. Mason, G. Hasenfuss, L. Maier, 2015, Cardiovascular research.

Antiarrhythmic effects of dantrolene in human diseased cardiomyocytes.

J. Gummert, G. Hasenfuss, L. Maier, 2017, Heart rhythm.

Molecular and Functional Relevance of NaV1.8-Induced Atrial Arrhythmogenic Triggers in a Human SCN10A Knock-Out Stem Cell Model

K. Streckfuss-Bömeke, S. Sossalla, N. Dybkova, 2023, International journal of molecular sciences.

Generation of homozygous Nav1.8 knock-out iPSC lines by CRISPR Cas9 genome editing to investigate a potential new antiarrhythmic strategy.

K. Streckfuss-Bömeke, S. Sossalla, N. Hartmann, 2022, Stem Cell Research.

The combined effects of ranolazine and dronedarone on human atrial and ventricular electrophysiology.

J. Gummert, F. Mason, G. Hasenfuss, 2016, Journal of molecular and cellular cardiology.

Role of late sodium current as a potential arrhythmogenic mechanism in the progression of pressure-induced heart disease.

G. Hasenfuss, L. Maier, K. Toischer, 2013, Journal of molecular and cellular cardiology.