Jian Wang

发表

Hormonal regulation of glycine decarboxylase and its relationship to oxidative stress

T. Leff, R. Jog, Guohua Chen, 2021, Physiological reports.

Iron-Dependent Degradation of Apo-IRP1 by the Ubiquitin-Proteasome Pathway

A. Biederbick, R. Lill, C. Fillebeen, 2007, Molecular and Cellular Biology.

Iron-dependent degradation of IRP2 requires its C-terminal region and IRP structural integrity

K. Pantopoulos, Guohua Chen, Jian Wang, 2008, BMC Molecular Biology.

Sustained Hydrogen Peroxide Induces Iron Uptake by Transferrin Receptor-1 Independent of the Iron Regulatory Protein/Iron-responsive Element Network*

S. Mueller, B. Andriopoulos, K. Pantopoulos, 2007, Journal of Biological Chemistry.

Glycine decarboxylase is a target for transcriptional repressor Snail

S. Lucas, Guohua Chen, Jian Wang, 2014, Cancer & Metabolism.

Insulin-like Growth Factor-I Receptor and Insulin Receptor Association with a Src Homology-2 Domain-containing Putative Adapter*

H. Riedel, Jian Wang, 1998, The Journal of Biological Chemistry.

FDXR regulates TP73 tumor suppressor via IRP2 to modulate aging and tumor suppression

Yanhong Zhang, Xinbin Chen, Mingyi Chen, 2020, The Journal of pathology.

Role of mitochondrial dysfunction in cellular responses to S-(1,2-dichlorovinyl)-L-cysteine in primary cultures of human proximal tubular cells.

D. Putt, L. Lash, I. Papanayotou, 2008, Biochemical pharmacology.

Insights on Regulation and Function of the Iron Regulatory Protein 1 (IRP1)

K. Pantopoulos, Guohua Chen, Jian Wang, 2008, Hemoglobin.

Sodium Nitroprusside Promotes IRP2 Degradation via an Increase in Intracellular Iron and in the Absence of S Nitrosylation at C178

B. Andriopoulos, C. Fillebeen, K. Pantopoulos, 2006, Molecular and Cellular Biology.

Inhibition of transferrin receptor 1 transcription by a cell density response element.

K. Pantopoulos, Guohua Chen, Jian Wang, 2005, The Biochemical journal.

Nitric Oxide Inhibits the Degradation of IRP2

K. Pantopoulos, Guohua Chen, Jian Wang, 2005, Molecular and Cellular Biology.

The catalytic and conformational cycle of Aquifex aeolicus KDO8P synthase: role of the L7 loop.

T. Stemmler, D. Gatti, F. Kona, 2005, Biochemistry.

The combination of CUDC-907 and gilteritinib shows promising in vitro and in vivo antileukemic activity against FLT3-ITD AML

Jing Li, J. Taub, Tristan E. Knight, 2021, Blood Cancer Journal.

Loss of ABHD5 promotes the aggressiveness of prostate cancer cells

S. Aras, J. Granneman, Guoli Zhou, 2017, Scientific Reports.

EGFL9 promotes breast cancer metastasis by inducing cMET activation and metabolic reprogramming

Bin Zhang, Jiani Hu, Guojun Wu, 2019, Nature Communications.

A regulatory circuitry locking pluripotent stemness to embryonic stem cell: Interaction between threonine catabolism and histone methylation.

Guohua Chen, Jian Wang, 2019, Seminars in cancer biology.

Threonine Catabolism: An Unexpected Epigenetic Regulator of Mouse Embryonic Stem Cells

T. Leff, R. Jog, Guohua Chen, 2019, Handbook of Nutrition, Diet, and Epigenetics.

Ferredoxin reductase is critical for p53-dependent tumor suppression via iron regulatory protein 2

K. Lloyd, Yanhong Zhang, Wensheng Yan, 2017, Genes & development.

Regulation of cellular iron metabolism

Jian Wang, Kostas Pantopoulos, K. Pantopoulos, 2011, The Biochemical journal.

Overexpression of iron regulatory protein 1 suppresses growth of tumor xenografts.

C. Fillebeen, K. Pantopoulos, Guohua Chen, 2006, Carcinogenesis.

ABHD5 suppresses cancer cell anabolism through lipolysis-dependent activation of the AMPK/mTORC1 pathway

J. Granneman, Guoli Zhou, Aaron Lotvola, 2020, The Journal of biological chemistry.

The haemochromatosis protein HFE induces an apparent iron-deficient phenotype in H1299 cells that is not corrected by co-expression of beta 2-microglobulin.

K. Pantopoulos, Guohua Chen, Jian Wang, 2003, The Biochemical journal.

Threonine metabolism and embryonic stem cell self-renewal

Guohua Chen, Jian Wang, 2013, Current opinion in clinical nutrition and metabolic care.

Protein and ligand dynamics in 4-hydroxybenzoate hydroxylase

D. Gatti, M. Ortiz-Maldonado, B. Entsch, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Conditional Derepression of Ferritin Synthesis in Cells Expressing a Constitutive IRP1 Mutant

K. Pantopoulos, Jian Wang, 2002, Molecular and Cellular Biology.

Constitutive IRP 1 Mutant Synthesis in Cells Expressing a Conditional Derepression of Ferritin

K. Pantopoulos, Jian Wang, 2002 .

Grb10, a Positive, Stimulatory Signaling Adapter in Platelet-Derived Growth Factor BB-, Insulin-Like Growth Factor I-, and Insulin-Mediated Mitogenesis

Youping Deng, M. Moussaif, N. Yousaf, 1999, Molecular and Cellular Biology.

PSM, a mediator of PDGF-BB-, IGF-I-, and insulin-stimulated mitogenesis

Youping Deng, Yuyuan Zhao, N. Yousaf, 2000, Oncogene.

Iron-Mediated Degradation of IRP2, an Unexpected Pathway Involving a 2-Oxoglutarate-Dependent Oxygenase Activity

M. Hentze, M. Muckenthaler, B. Galy, 2004, Molecular and Cellular Biology.

Myeloperoxidase-derived Hypochlorous Acid Antagonizes the Oxidative Stress-mediated Activation of Iron Regulatory Protein 1*

S. Mueller, W. Stremmel, K. Pantopoulos, 2003, Journal of Biological Chemistry.

The pathway for IRP2 degradation involving 2-oxoglutarate-dependent oxygenase(s) does not require the E3 ubiquitin ligase activity of pVHL.

K. Pantopoulos, Jian Wang, 2005, Biochimica et biophysica acta.

Serine catabolism is essential to maintain mitochondrial respiration in mammalian cells

S. Aras, S. Lucas, Guohua Chen, 2018, Life Science Alliance.

The prolyl 4‐hydroxylase inhibitor ethyl‐3,4‐dihydroxybenzoate generates effective iron deficiency in cultured cells

K. Pantopoulos, P. Ponka, Guohua Chen, 2002, FEBS letters.

Grb10, a Positive, Stimulatory Signaling Adapter in Platelet-Derived Growth Factor BB-, Insulin-Like Growth Factor I-, and Insulin-Mediated Mitogenesis

Youping Deng, M. Moussaif, N. Yousaf, 1999, Molecular and Cellular Biology.

Mdig promotes oncogenic gene expression through antagonizing repressive histone methylation markers

Benjamin L. Kidder, Yao Fu, Liping Xu, 2020, Theranostics.

Loss of ABHD5 promotes the aggressiveness of prostate cancer cells

S. Aras, J. Granneman, Guoli Zhou, 2017, Scientific Reports.

Function of His185 in Aquifex aeolicus 3-deoxy-D-manno-octulosonate 8-phosphate synthase.

H. Duewel, J. Stuckey, R. Woodard, 2002, Journal of molecular biology.

Structure-based design of novel inhibitors of 3-deoxy-D-manno-octulosonate 8-phosphate synthase.

R. Woodard, D. Gatti, C. Grison, 2003, Drug design and discovery.

Serine catabolism is essential to maintain mitochondrial respiration in mammalian cells

S. Aras, S. Lucas, Guohua Chen, 2018, Life Science Alliance.

Pharmacological Inhibitors of NAD Biosynthesis as Potential An ticancer Agents.

Q. Dou, S. Lucas, Ghazal Nabil, 2017, Recent patents on anti-cancer drug discovery.

Quantitative analysis of intracellular nucleoside triphosphates and other polar metabolites using ion pair reversed-phase liquid chromatography coupled with tandem mass spectrometry.

G. Bepler, Yingtao Zhang, Jianmei Wu, 2015, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Grb10, a Positive, Stimulatory Signaling Adapter in Platelet-Derived Growth Factor BB-, Insulin-Like Growth Factor I-, and Insulin-Mediated Mitogenesis

Youping Deng, N. Yousaf, H. Riedel, 1999, Molecular and Cellular Biology.