P. Choi

发表

Genome-scale genetic screening identifies PRMT1 as a critical vulnerability in castration-resistant prostate cancer

John G Doench, W. Hahn, Sylvan C. Baca, 2020, European Journal of Cancer.

A genome-scale CRISPR screen reveals PRMT1 as a critical regulator of androgen receptor signaling in prostate cancer

John G Doench, W. Hahn, Sylvan C. Baca, 2020, bioRxiv.

Activation of Cre Recombinase Alone Can Induce Complete Tumor Regression

D. Felsher, S. Casey, Yulin Li, 2014, PloS one.

Copy-number and gene dependency analysis reveals partial copy loss of wild-type SF3B1 as a novel cancer vulnerability

W. Hahn, G. Wei, R. Beroukhim, 2017, eLife.

Chromatin Looping Shapes KLF5-Dependent Transcriptional Programs in Human Epithelial Cancers

Swneke D. Bailey, J. Francis, Xiaojun Yang, 2020, Cancer Research.

Lymphomas that recur after MYC suppression continue to exhibit oncogene addiction

Kavya Rakhra, Sylvia K Plevritis, Andrew J Gentles, 2011, Proceedings of the National Academy of Sciences.

Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer

Ashton C. Berger, P. Tamayo, W. Hahn, 2018, Nature Genetics.

Survival and Death Signals Can Predict Tumor Response to Therapy After Oncogene Inactivation

Lawrence H. Schwartz, Nicholas P. Hughes, Dean W. Felsher, 2011, Science Translational Medicine.

Identification and Characterization of Oncogenic SOS1 Mutations in Lung Adenocarcinoma

M. Meyerson, P. Choi, D. Cai, 2017, Molecular Cancer Research.

Targeted genomic rearrangements using CRISPR/Cas technology Please share how this access benefits you. Your story matters

M. Meyerson, P. Choi, 2014 .

Author Correction: Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells

Ashton C. Berger, W. Hahn, M. Meyerson, 2018, Nature Communications.

RNA-binding proteins of COSMIC importance in cancer.

A. Thomas-Tikhonenko, P. Choi, 2021, The Journal of clinical investigation.

A predominant enhancer co-amplified with the SOX2 oncogene is necessary and sufficient for its expression in squamous cancer

Swneke D. Bailey, A. Bass, A. Cherniack, 2021, Nature Communications.

Identification of cancer cytotoxic modulators of PDE3A by predictive chemogenomics

Benito Munoz, Paul A Clemons, Aviad Tsherniak, 2015, Nature chemical biology.

Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers

Marcin Imielinski, Matthew Meyerson, Andrew D Cherniack, 2015, Nature Genetics.

Targeted genomic rearrangements using CRISPR/Cas technology

Matthew Meyerson, M. Meyerson, Peter S. Choi, 2014, Nature Communications.

Multi-Omics Analysis Identifies MGA as a Negative Regulator of the MYC Pathway in Lung Adenocarcinoma

M. Meyerson, S. Carr, J. Francis, 2019, Molecular Cancer Research.

Somatic Superenhancer Duplications and Hotspot Mutations Lead to Oncogenic Activation of the KLF5 Transcription Factor.

Aviad Tsherniak, Gavin Ha, William C Hahn, 2017, Cancer discovery.

An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer

Angela N. Brooks, John G Doench, W. Hahn, 2018, eLife.

Title An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer

Angela N. Brooks, John G Doench, W. Hahn, 2018 .

A Pan-Cancer Analysis of Transcriptome Changes Associated with Somatic Mutations in U2AF1 Reveals Commonly Altered Splicing Events

Chandra Sekhar Pedamallu, Angela N. Brooks, Gad Getz, 2014, PloS one.

P2Y-like receptor, GPR105 (P2Y14), identifies and mediates chemotaxis of bone-marrow hematopoietic stem cells.

D. Haber, D. Scadden, D. Dombkowski, 2003, Genes & development.

MET Exon 14 Mutation Encodes an Actionable Therapeutic Target in Lung Adenocarcinoma.

Angela N. Brooks, Sergio E. Wong, M. Meyerson, 2017, Cancer research.

Functional Analysis of Somatic Mutations in Lung Cancer

M. Meyerson, A. Berger, A. Ramachandran, 2015 .

The interaction between Myc and Miz1 is required to antagonize TGFbeta-dependent autocrine signaling during lymphoma formation and maintenance.

D. Felsher, T. Möröy, M. Eilers, 2010, Genes & development.

MYC through miR-17-92 suppresses specific target genes to maintain survival, autonomous proliferation, and a neoplastic state.

D. Dill, D. Felsher, S. Casey, 2014, Cancer cell.

Author Correction: Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells

Ashton C. Berger, W. Hahn, M. Meyerson, 2018, Nature Communications.

Flowing cells through pulsed electric fields efficiently purges stem cell preparations of contaminating myeloma cells while preserving stem cell function.

J. Gribben, A. Craiu, P. Richardson, 2005, Blood.

Oncogene Inactivation Survival and Death Signals Can Predict Tumor Response to Therapy After

L. Schwartz, D. Paik, D. Felsher, 2011 .

Addiction to multiple oncogenes can be exploited to prevent the emergence of therapeutic resistance

D. Felsher, Yulin Li, P. Choi, 2014, Proceedings of the National Academy of Sciences.

BIM mediates oncogene inactivation-induced apoptosis in multiple transgenic mouse models of acute lymphoblastic leukemia

D. Felsher, Yulin Li, A. Fan, 2016, Oncotarget.

miR-17–92 explains MYC oncogene addiction

D. Felsher, S. Casey, Yulin Li, 2014, Molecular & cellular oncology.

Oncogene addiction: resetting the safety switch?

D. Felsher, Yulin Li, P. Choi, 2014, Oncotarget.

Addiction to multiple oncogenes can be exploited to prevent the emergence of therapeutic resistance

D. Felsher, Yulin Li, P. Choi, 2014, Proceedings of the National Academy of Sciences.