P. Lumley

发表

Effects of hypoxia, elevated K+ and acidosis on the potency of verapamil, diltiazem and nifedipine in the guinea‐pig isolated papillary muscle

M. J. Robertson, P. Lumley, 1989, British journal of pharmacology.

A method for quantitating platelet aggregation and analyzing drug-receptor interactions on platelets in whole blood in vitro.

P. Lumley, P. Humphrey, 1981, Journal of pharmacological methods.

Evidence from agonist and antagonist studies to suggest that the β1‐adrenoceptors subserving the positive inotropic and chronotropic responses of the heart do not belong to two separate subgroups

K. Broadley, K. Broadley, P. Lumley, 1977, The Journal of pharmacy and pharmacology.

Analysis of the inotropic: chronotropic selectivity of dobutamine and dopamine in anaethetised dogs and guinea-pig isolated atria.

K. Broadley, G. P. Levy, P. Lumley, 1977, Cardiovascular research.

The Effect of a Metalloproteinase Inhibitor (GI5402) on Tumor Necrosis Factor- (TNF-) and TNF- Receptors During Human Endotoxemia

S. Deventer, T. Poll, P. Dekkers, 1999 .

Protection against Helicobacter pylori infection by intestinal immunisation with a 50/52-kDa subunit protein.

S. Harris, K. Beagley, R. Clancy, 1999, FEMS immunology and medical microbiology.

COMPARISON OF THE ACTIONS OF U‐46619, A PROSTAGLANDIN H2‐ANALOGUE, WITH THOSE OF PROSTAGLANDIN H2 AND THROMBOXANE A2 ON SOME ISOLATED SMOOTH MUSCLE PREPARATIONS

R. A. Coleman, G. P. Levy, I. Kennedy, 1981, British journal of pharmacology.

Rapid effect of inhaled fluticasone propionate on airway responsiveness to adenosine 5'-monophosphate in mild asthma.

M. W. Jensen, B. O'connor, A. Wright, 2002, The Journal of allergy and clinical immunology.

Preliminary characterisation of three types of prostanoid receptor mediating smooth muscle contraction

R. A. Coleman, G. P. Levy, I. Kennedy, 2007 .

Differential blockade of guinea-pig atrial rate and force responses to (--)-noradrenaline by practolol - an uptake phenomenon.

K. Broadley, P. Lumley, 1975, European journal of pharmacology.

AH6809, a prostaglandin DP‐receptor blocking drug on human platelets

P. Lumley, R. Keery, 1988, British journal of pharmacology.

Characteristics of the binding of [3H]‐GR32191 to the thromboxane (TP‐) receptor of human platelets

R. Armstrong, P. Lumley, P. Humphrey, 1993, British journal of pharmacology.

GR32191, a highly potent and specific thromboxane A2 receptor blocking drug on platelets and vascular and airways smooth muscle in vitro

B. P. White, P. Lumley, P. Humphrey, 1989, British journal of pharmacology.

Thromboxane Receptor Blockers

Garrick, I., P. Lumley, 2005 .

Prevention of Intra-Coronary Thrombosis in the Anaesthetised Dog: The Importance of Thromboxane A2 and Thrombin

A. Sullivan, B. P. White, P. Lumley, 1994, Thrombosis and Haemostasis.

Effect ofthespecific thromboxane receptorblocking drugAH23848inpatients withangina pectoris

D. Woodings, M. Been, S. Ince, 1986 .

Preliminary assessment of a novel thromboxane A2 receptor-blocking drug, GR32191, in healthy subjects.

M. Thomas, P. Lumley, 1990, Circulation.

Pathophysiological actions of thromboxane A2 and their pharmacological antagonism by thromboxane receptor blockade with GR32191.

E. Hornby, P. Lumley, P. Humphrey, 1990, Circulation.

Effects of intravenous infusions of prostaglandin D2 in man.

C. Dollery, M. Murphy, D. Heavey, 1984, Prostaglandins.

Comparison of the potencies of some prostaglandins as vasodilators in three vascular beds of the anaesthetised dog.

R. A. Coleman, I. Kennedy, P. Lumley, 1982, European journal of pharmacology.

Preliminary clinical studies with thromboxane synthase inhibitors and thromboxane receptor blockers. A review.

P. Lumley, G. Fiddler, 1990, Circulation.

Imaging thrombus with radiolabelled monoclonal antibody to platelets.

N. Hogg, D. Snook, A. Epenetos, 1986, British medical journal.

Prostanoid receptors — the development of a working classification

R. A. Coleman, I. Kennedy, P. Lumley, 1984 .

VASCULAR OCCLUSION AH 23848 * : a thromboxane receptor-blocking drug that can clarify the pathophysiologic role of thromboxane A 2

R. A. Coleman, P. Hallett, M. Carter, 2005 .

patients with angina pectoris . receptor blocking drug AH 23848 in Effect of the specific thromboxane

D. Woodings, D. Debono, M. Been, 2005 .

Effect of the specific thromboxane receptor blocking drug AH23848 in patients with angina pectoris.

D. Woodings, M. Been, S. Ince, 1986, British heart journal.

Thromboxane (Tx) A2 receptor blockade and TxA2 synthase inhibition alone and in combination: comparison of anti‐aggregatory efficacy in human platelets

K. Wharton, B. P. White, P. Lumley, 1991, British journal of pharmacology.

The Metalloproteinase Inhibitor GI5402 Inhibits Endotoxin-Induced Soluble CD27 and CD16 Release in Healthy Humans

T. van der Poll, S. V. van Deventer, P. Dekkers, 2000, Infection and Immunity.

The Effect of a Metalloproteinase Inhibitor (GI5402) on Tumor Necrosis Factor- (TNF-) and TNF- Receptors During Human Endotoxemia

S. Deventer, T. Poll, P. Dekkers, 1999 .

INITIAL STUDIES IN MAN WITH A NOVEL THROMBOXANE RECEPTOR BLOCKING DRUG GR32191

P. Ballard, J. O'brien, M. Thomas, 1987, Thrombosis and Haemostasis.

Studies on the characterization of prostanoid receptors.

R. A. Coleman, I. Kennedy, P. Lumley, 1983, Advances in prostaglandin, thromboxane, and leukotriene research.

Orally active non-peptide fibrinogen receptor (GpIIb/IIIa) antagonists: identification of 4-[4-[4-(aminoiminomethyl)phenyl]-1-piperazinyl]-1-piperidineacetic acid as a long-acting, broad-spectrum antithrombotic agent.

J. Kitchin, B. Judkins, K. Smith, 1994, Journal of medicinal chemistry.

Studies on the characterisation of prostanoid receptors: a proposed classification.

R. A. Coleman, G. P. Levy, I. Kennedy, 1982, Prostaglandins.

SELECTIVE RESERPINE‐INDUCED SUPERSENSITIVITY OF THE POSITIVE INOTROPIC AND CHRONOTROPIC RESPONSES TO ISOPRENALINE AND SALBUTAMOL IN GUINEA‐PIG ISOLATED ATRIA

K. Broadley, P. Lumley, 1977, British journal of pharmacology.

Synthesis and pharmacological evaluation of combined thromboxane receptor antagonist/synthase inhibitors: pyridine-containing sulphonamido acids

N. Pike, H. Finch, G. Robertson, 1991 .

Reduction in the number of thromboxane receptors on human platelets after exposure to GR32191

R. Armstrong, P. Lumley, P. Humphrey, 1993, British journal of pharmacology.

Use of an anti‐platelet monoclonal antibody F(ab')2 fragment for imaging thrombus

A. Peters, J. Lavender, P. Lumley, 1988, Nuclear medicine communications.

A Specific Thromboxane Receptor Blocking Drug, AH23848, Reduces Platelet Deposition on Vascular Grafts in Man

C. McCollum, A. Peters, I. Lane, 1990, Thrombosis and Haemostasis.

Characteristics of [3H]-GR 32191 binding to the thromboxane (TP) receptor of human platelets.

R. Armstrong, P. Lumley, P. Humphrey, 1989, British journal of pharmacology.

THE EFFECTS OF GR32191, A NEW THROMBOXANE RECEPTOR BLOCKING DRUG,ON PLATELETS AND VASCULAR SMOOTH MUSCLE IN VITRO

P. Hallett, R. T. Brittain, E. Hornby, 1987, Thrombosis and Haemostasis.

The pharmacodynamics and pharmacokinetics of a novel thromboxane receptor blocking drug vapiprost (GR32191) after single intravenous doses in healthy subjects.

M. Charter, M. Thomas, J. Chilton, 1991, British journal of clinical pharmacology.

U-46619, a selective thromboxane A2-like agonist? [proceedings].

R. A. Coleman, G. P. Levy, I. Kennedy, 1980, British journal of pharmacology.

THE SELECTIVE POSITIVE INOTROPIC ACTIVITY OF 2− ALKYL− 1,3− DIOXO− 5, 10− DIHYDROIMIDAZO[1,5−b]ISOQUINOLINES

E. C. Fraser, P. Lumley, G.A. Smail, 1977, The Journal of pharmacy and pharmacology.