E. Jiménez

发表

Identification and Characterization of Hundreds of Potent and Selective Inhibitors of Trypanosoma brucei Growth from a Kinase-Targeted Library Screening Campaign

Gonzalo Colmenarejo, William G. Devine, T. Geary, 2014, PLoS neglected tropical diseases.

The small-molecule SMARt751 reverses Mycobacterium tuberculosis resistance to ethionamide in acute and chronic mouse models of tuberculosis

G. Drewes, Pablo Gamallo, Markus Boesche, 2022, Science Translational Medicine.

GSK2556286 Is a Novel Antitubercular Drug Candidate Effective In Vivo with the Potential To Shorten Tuberculosis Treatment

Robert H Bates, N. Fotouhi, G. Besra, 2022, bioRxiv.

Exploring the SAR of the β-Ketoacyl-ACP Synthase Inhibitor GSK3011724A and Optimization around a Genotoxic Metabolite.

Robert H Bates, Fraser Cunningham, C. Chung, 2020, ACS infectious diseases.

Antifungal Activities of Two New Azasordarins, GW471552 and GW471558, in Experimental Models of Oral and Vulvovaginal Candidiasis in Immunosuppressed Rats

J. Regadera, S. Ferrer, Inmaculada Santos, 2001, Antimicrobial Agents and Chemotherapy.

Therapeutic Efficacies of GW471552 and GW471558, Two New Azasordarin Derivatives, against Pneumocystosis in Two Immunosuppressed-Rat Models

E. Dei‐Cas, D. Gargallo‐Viola, E. Aliouat, 2002, Antimicrobial Agents and Chemotherapy.

Antifungal Efficacy of GM237354, a Sordarin Derivative, in Experimental Oral Candidiasis in Immunosuppressed Rats

J. Regadera, Inmaculada Santos, D. Gargallo‐Viola, 2001, Antimicrobial Agents and Chemotherapy.

A Murine Model of falciparum-Malaria by In Vivo Selection of Competent Strains in Non-Myelodepleted Mice Engrafted with Human Erythrocytes

P. Rosenthal, J. Regadera, D. Pompliano, 2008, PloS one.

Tetrahydropyrazolo[1,5-a]Pyrimidine-3-Carboxamide and N-Benzyl-6′,7′-Dihydrospiro[Piperidine-4,4′-Thieno[3,2-c]Pyran] Analogues with Bactericidal Efficacy against Mycobacterium tuberculosis Targeting MmpL3

N. Loman, C. Constantinidou, M. Pallen, 2013, PloS one.

A Focused Screen Identifies Antifolates with Activity on Mycobacterium tuberculosis.

D. Sherman, Gonzalo Colmenarejo, Anuradha Kumar, 2015, ACS infectious diseases.

Easy-To-Synthesize Spirocyclic Compounds Possess Remarkable in Vivo Activity against Mycobacterium tuberculosis.

Katrina A. Badiola, M. Todd, P. Rutledge, 2018, Journal of medicinal chemistry.

Inhibiting mycobacterial tryptophan synthase by targeting the inter-subunit interface

N. Loman, G. Besra, David Barros, 2017, Scientific Reports.

Development of Pneumocystosis Animal Models: Corticosteriod‐Treated Wistar Rat; SCID Mouse and Nude Rat.

E. Dei‐Cas, P. Delcourt, D. Gargallo‐Viola, 1997, Journal of Eukaryotic Microbiology.

Small-molecule SMARt751 hypersensitizes M. tuberculosis resistant to ethionamide by upregulating the mymA operon

G. Drewes, Markus Boesche, R. Wintjens, 2022 .

A Focused Screen Identifies Antifolates with Activity on Mycobacterium tuberculosis.

D. Sherman, Gonzalo Colmenarejo, Anuradha Kumar, 2015, ACS infectious diseases.