K. Schewe

Haemagglutinin substitutions N125D, D127E, D222G and R223Q improve replicative fitness and vaccine effectiveness of an A/H1N1pdm09 live attenuated influenza vaccine virus by enhancing α-2,6 receptor binding

A. Nuccitelli, Giulia Tamburrino, O. Dibben, 2022, PLoS pathogens.

Novel aldosterone synthase inhibitors with extended carbocyclic skeleton by a combined ligand-based and structure-based drug design approach.

A. Bisi, S. Gobbi, M. Negri, 2008, Journal of medicinal chemistry.

Sequential delivery of LAIV and SARS-CoV-2 in the ferret model can reduce SARS-CoV-2 shedding and does not result in enhanced lung pathology

M. Carroll, F. Salguero, A. Marriott, 2021, bioRxiv.

Defining the root cause of reduced H1N1 live attenuated influenza vaccine effectiveness: low viral fitness leads to inter-strain competition

O. Dibben, H. Bright, K. Schewe, 2021, NPJ vaccines.

CYP19 (aromatase): exploring the scaffold flexibility for novel selective inhibitors.

R. Hartmann, G. Sbardella, R. Ragno, 2008, Bioorganic & medicinal chemistry.

Imidazolylmethylbenzophenones as highly potent aromatase inhibitors.

Silvia Gobbi, Maurizio Recanatini, Andrea Cavalli, 2007, Journal of medicinal chemistry.

Etomidate Unmasks Intraadrenal Regulation of Steroidogenesis and Proliferation in Adrenal Cortical Cell Lines

R. Hartmann, M. Fassnacht, M. Zink, 2010, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Defining the root cause of reduced H1N1 live attenuated influenza vaccine effectiveness: low viral fitness leads to inter-strain competition

O. Dibben, H. Bright, K. Schewe, 2021, npj Vaccines.

In vivo active aldosterone synthase inhibitors with improved selectivity: lead optimization providing a series of pyridine substituted 3,4-dihydro-1H-quinolin-2-one derivatives.

R. Hartmann, S. Lucas, B. Birk, 2008, Journal of medicinal chemistry.

Overcoming undesirable CYP1A2 inhibition of pyridylnaphthalene-type aldosterone synthase inhibitors: influence of heteroaryl derivatization on potency and selectivity.

M. Negri, R. Hartmann, S. Lucas, 2008, Journal of medicinal chemistry.