A. N. Matthew

发表

Targeting Drug Resistance In HCV NS3/4A Protease: Mechanisms And Inhibitor Design Strategies

A. N. Matthew, 2018 .

Purification of metal-dependent lysine deacetylases with consistently high activity.

M. Bratton, Terry J Watt, Elena Y Glotser, 2018, Protein expression and purification.

Drug Design Strategies to Avoid Resistance in Direct-Acting Antivirals and Beyond.

C. Schiffer, E. Nalivaika, Akbar Ali, 2021, Chemical reviews.

Resistance outside the substrate envelope: hepatitis C NS3/4A protease inhibitors

C. Schiffer, Ayşegül Özen, Kristina L. Prachanronarong, 2019, Critical reviews in biochemistry and molecular biology.

Deciphering the Molecular Mechanism of HCV Protease Inhibitor Fluorination as a General Approach to Avoid Drug Resistance.

C. Schiffer, Akbar Ali, Adam K. Hedger, 2022, Journal of molecular biology.

Deciphering the Molecular Mechanism of HCV Protease Inhibitor Fluorination as a General Approach to Avoid Drug Resistance

C. Schiffer, E. Chan, Akbar Ali, 2021, bioRxiv.

Discovery of Quinoxaline-Based P1-P3 Macrocyclic NS3/4A Protease Inhibitors with Potent Activity against Drug-Resistant Hepatitis C Virus Variants.

C. Schiffer, C. Petropoulos, Wei Huang, 2021, Journal of medicinal chemistry.

Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors

C. Schiffer, Akbar Ali, Adam K. Hedger, 2020, mBio.

Molecular Mechanism of Resistance in a Clinically Significant Double-Mutant Variant of HCV NS3/4A Protease.

C. Schiffer, C. Petropoulos, Wei Huang, 2018, Structure.

Quinoxaline-Based Linear HCV NS3/4A Protease Inhibitors Exhibit Potent Activity against Drug Resistant Variants.

C. Schiffer, C. Petropoulos, Wei Huang, 2018, ACS medicinal chemistry letters.

Hepatitis C Virus NS3/4A Protease Inhibitors Incorporating Flexible P2 Quinoxalines Target Drug Resistant Viral Variants.

Wei Huang, Akbar Ali, Celia A Schiffer, 2017, Journal of medicinal chemistry.

Evolution of robotic-assisted kidney transplant: successes and barriers to overcome

R. Autorino, C. Bhati, L. Hampton, 2021, Current opinion in urology.

Mavyret: A Pan-Genotypic Combination Therapy for the Treatment of Hepatitis C InfectionPublished as part of the Biochemistry series "Biochemistry to Bedside".

C. Schiffer, Nese Kurt Yilmaz, A. N. Matthew, 2017, Biochemistry.