Louise Thiesen

Discovery and Optimization of 5-Hydroxy-Diclofenac toward a New Class of Ligands with Nanomolar Affinity for the CaMKIIα Hub Domain.

C. Bundgaard, P. Wellendorph, B. Frølund, 2022, Journal of medicinal chemistry.

The γ-hydroxybutyric acid (GHB) analogue NCS-382 is a substrate for both monocarboxylate transporters subtypes 1 and 4.

S. Pedersen, P. Wellendorph, C. Crocoll, 2019, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

In Vitro and In Vivo Evidence for Active Brain Uptake of the GHB Analog HOCPCA by the Monocarboxylate Transporter Subtype 1

J. Kehler, C. Bundgaard, P. Wellendorph, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Pharmacological Characterization of [3H]ATPCA as a Substrate for Studying the Functional Role of the Betaine/GABA Transporter 1 and the Creatine Transporter.

C. Bundgaard, P. Wellendorph, B. Frølund, 2017, ACS chemical neuroscience.

The CaMKIIα hub ligand Ph-HTBA promotes neuroprotection after focal ischemic stroke by a distinct molecular interaction.

A. Clarkson, P. Wellendorph, B. Frølund, 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Lack of evidence for synaptic high‐affinity γ‐hydroxybutyric acid (GHB) transport in rat brain synaptosomes and 11 Na+‐dependent SLC neurotransmitter transporters

P. Wellendorph, B. Frølund, Louise Thiesen, 2019, Journal of neurochemistry.

Radiosynthesis and Evaluation of [11C]3-Hydroxycyclopent-1-enecarboxylic Acid as Potential PET Ligand for the High-Affinity γ-Hydroxybutyric Acid Binding Sites.

C. Bundgaard, G. Knudsen, S. Lehel, 2017, ACS chemical neuroscience.

Five-membered N-heterocyclic Scaffolds as Novel Amino Bioisosteres at -Aminobutyric Acid (GABA) Type A Receptors and GABA Transporters.

D. Gloriam, B. Rolando, D. Boschi, 2019, Journal of medicinal chemistry.

Exploring the NCS-382 Scaffold for CaMKIIα Modulation: Synthesis, Biochemical Pharmacology, and Biophysical Characterization of Ph-HTBA as a Novel High-Affinity Brain-Penetrant Stabilizer of the CaMKIIα Hub Domain.

P. Wellendorph, B. Frølund, M. Shehata, 2022, Journal of medicinal chemistry.

GAT3 selective substrate l-isoserine upregulates GAT3 expression and increases functional recovery after a focal ischemic stroke in mice

N. O. Dalby, A. Clarkson, P. Wellendorph, 2017, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Pharmacological Characterization of [3H]ATPCA as a Substrate for Studying the Functional Role of the Betaine/GABA Transporter 1 and the Creatine Transporter.

C. Bundgaard, P. Wellendorph, B. Frølund, 2017, ACS chemical neuroscience.

In Vitro and In Vivo Evidence for Active Brain Uptake of the GHB Analog HOCPCA by the Monocarboxylate Transporter Subtype 1

J. Kehler, C. Bundgaard, P. Wellendorph, 2015, The Journal of Pharmacology and Experimental Therapeutics.