Weixue Huang

发表

Structure-guided engineering of a Thermobifida fusca cutinase for enhanced hydrolysis on natural polyester substrate

Shuguang Yuan, Jiahai Zhou, Lingqia Su, 2020, Bioresources and Bioprocessing.

Colorimetric determination of the early biomarker hypoxia-inducible factor-1 alpha (HIF-1α) in circulating exosomes by using a gold seed-coated with aptamer-functionalized Au@Au core-shell peroxidase mimic

Hua Zhou, Pei Luo, Linsen Qing, 2019, Microchimica Acta.

Structural insights into xylanase mutant 254RL1 for improved activity and lower pH optimum.

Jiahai Zhou, Guimin Zhang, Lian Wu, 2021, Enzyme and microbial technology.

Discovery of a Highly Potent and Selective Dual PROTAC Degrader of CDK12 and CDK13

A. Chinnaiyan, J. Tien, Zhen Wang, 2022, Journal of medicinal chemistry.

Application of serum exosomal hypoxia-inducible factor-1 alpha (HIF-1α) as potential circulating biomarker for bacterial peritonitis

Hua Zhou, Pei Luo, Xiaoyi Chen, 2021, Bioengineered.

Targeting the Non-Catalytic Functions: a New Paradigm for Kinase Drug Discovery?

Zhen Wang, Ke Ding, Xiaomei Ren, 2022, Journal of medicinal chemistry.

Discovery of AXL Degraders with Improved Potencies in Triple-Negative Breast Cancer (TNBC) Cells.

Yongxing Wang, Zheng-chao Tu, Zhen Wang, 2023, Journal of medicinal chemistry.

Rg1 prevents myocardial hypoxia/reoxygenation injury by regulating mitochondrial dynamics imbalance via modulation of glutamate dehydrogenase and mitofusin 2.

Liang Liu, Hua Zhou, Zhifeng Zhang, 2016, Mitochondrion.

Discovery of a First-in-Class Degrader for the Lipid Kinase PIKfyve

A. Chinnaiyan, Yuzhuo Wang, Y. Qiao, 2023, Journal of medicinal chemistry.

A Novel Photocaged B-RafV600E Inhibitor toward Precise Melanoma Treatment.

Zhen Wang, Ke Ding, Xiaomei Ren, 2022, Bioorganic & medicinal chemistry letters.