Giannamaria Annunziato

发表

Accepting the Invitation to Open Innovation in Malaria Drug Discovery: Synthesis, Biological Evaluation, and Investigation on the Structure-Activity Relationships of Benzo[b]thiophene-2-carboxamides as Antimalarial Agents.

S. Parapini, M. Zółkiewski, Marco Pieroni, 2017, Journal of medicinal chemistry.

Investigational Studies on a Hit Compound Cyclopropane-Carboxylic Acid Derivative Targeting O-Acetylserine Sulfhydrylase as a Colistin Adjuvant.

A. Mozzarelli, S. Bettati, Marialaura Marchetti, 2021, ACS infectious diseases.

CYCLOSERINE ENANTIOMERS ARE REVERSIBLE INHIBITORS OF HUMAN ALANINE:GLYOXYLATE AMINOTRANSFERASE: IMPLICATIONS FOR PRIMARY HYPEROXALURIA TYPE 1.

F. Cutruzzolà, A. Faccini, Marco Pieroni, 2019, The Biochemical journal.

Discovering a new class of antifungal agents that selectively inhibits microbial carbonic anhydrases

C. Supuran, C. Capasso, A. Angeli, 2018, Journal of enzyme inhibition and medicinal chemistry.

Exploring the chemical space around N-(5-nitrothiazol-2-yl)-1,2,3-thiadiazole-4-carboxamide, a hit compound with Serine Acetyltransferase (SAT) inhibitory properties

E. Carosati, S. Bettati, Marialaura Marchetti, 2022, Results in Chemistry.

Biochemical Characterization of Aspergillus fumigatus AroH, a Putative Aromatic Amino Acid Aminotransferase

L. Romani, T. Zelante, N. Keller, 2018, Front. Mol. Biosci..

Inhibitors of O-Acetylserine Sulfhydrylase with a Cyclopropane-Carboxylic Acid Scaffold Are Effective Colistin Adjuvants in Gram Negative Bacteria

S. Bettati, Marialaura Marchetti, B. Campanini, 2022, Pharmaceuticals.

Refining the structure−activity relationships of 2-phenylcyclopropane carboxylic acids as inhibitors of O-acetylserine sulfhydrylase isoforms

A. Mozzarelli, A. Jirgensons, S. Bettati, 2018, Journal of Enzyme Inhibition and Medicinal Chemistry.

Antimicrobial peptides (AMPs): a patent review (2015–2020)

G. Costantino, Giannamaria Annunziato, 2020, Expert opinion on therapeutic patents.

Identification of Human Alanine–Glyoxylate Aminotransferase Ligands as Pharmacological Chaperones for Variants Associated with Primary Hyperoxaluria Type 1

Marco Pieroni, G. Costantino, Mirco Dindo, 2022, Journal of medicinal chemistry.

Inhibition of Nonessential Bacterial Targets: Discovery of a Novel Serine O-Acetyltransferase Inhibitor.

A. Mozzarelli, S. Bettati, B. Campanini, 2020, ACS medicinal chemistry letters.

Cyclopropane-1,2-dicarboxylic acids as new tools for the biophysical investigation of O-acetylserine sulfhydrylases by fluorimetric methods and saturation transfer difference (STD) NMR

A. Mozzarelli, S. Bettati, B. Campanini, 2016, Journal of enzyme inhibition and medicinal chemistry.

Rational Design, Synthesis, and Preliminary Structure-Activity Relationships of α-Substituted-2-Phenylcyclopropane Carboxylic Acids as Inhibitors of Salmonella typhimurium O-Acetylserine Sulfhydrylase.

A. Mozzarelli, S. Bettati, B. Campanini, 2016, Journal of medicinal chemistry.

2-Aminooxazole as a Novel Privileged Scaffold in Antitubercular Medicinal Chemistry.

Marco Pieroni, Elisa Azzali, G. Costantino, 2020, ACS medicinal chemistry letters.

Discovery of novel fragments inhibiting O-acetylserine sulphhydrylase by combining scaffold hopping and ligand–based drug design

M. Welch, A. Mozzarelli, A. Jirgensons, 2018, Journal of enzyme inhibition and medicinal chemistry.

Metabolite Profiling and Bioactivities of Leaves, Stems, and Flowers of Rumex usambarensis (Dammer) Dammer, a Traditional African Medicinal Plant

L. Righetti, G. Costantino, C. S. Cabassi, 2023, Plants.

Strategies to Overcome Antimicrobial Resistance (AMR) Making Use of Non-Essential Target Inhibitors: A Review

Giannamaria Annunziato, 2019, International journal of molecular sciences.

A Competitive O-Acetylserine Sulfhydrylase Inhibitor Modulates the Formation of Cysteine Synthase Complex

A. Mozzarelli, S. Cannistraro, L. Ronda, 2021, Catalysts.

Discovery of New Potential Anti‐Infective Compounds Based on Carbonic Anhydrase Inhibitors by Rational Target‐Focused Repurposing Approaches

C. Supuran, D. Vullo, C. Capasso, 2016, ChemMedChem.

The Aryl Hydrocarbon Receptor (AhR) Mediates the Counter-Regulatory Effects of Pelargonidins in Models of Inflammation and Metabolic Dysfunctions

S. Marchianò, Michele Biagioli, E. Distrutti, 2019, Nutrients.

Further insights into the SAR of α-substituted cyclopropylamine derivatives as inhibitors of histone demethylase KDM1A.

C. Mercurio, M. Villa, M. Varasi, 2015, European journal of medicinal chemistry.

Sodium Hyaluronate Nanocomposite Respirable Microparticles to Tackle Antibiotic Resistance with Potential Application in Treatment of Mycobacterial Pulmonary Infections

F. Sonvico, Marco Pieroni, M. Viveiros, 2019, Pharmaceutics.

Expanding the knowledge around antitubercular 5-(2-aminothiazol-4-yl)isoxazole-3-carboxamides: Hit-to-lead optimization and release of a novel antitubercular chemotype via scaffold derivatization.

T. Dick, Marco Pieroni, G. Costantino, 2022, European journal of medicinal chemistry.

Discovery of Substituted (2-Aminooxazol-4-yl)Isoxazole-3-carboxylic Acids as Inhibitors of Bacterial Serine Acetyltransferase in the Quest for Novel Potential Antibacterial Adjuvants

A. Mozzarelli, S. Bettati, B. Campanini, 2021, Pharmaceuticals.

Integration of Enhanced Sampling Methods with Saturation Transfer Difference Experiments to Identify Protein Druggable Pockets

Marco Pieroni, Gabriele Costantino, Agostino Bruno, 2018, J. Chem. Inf. Model..

In vitro Digestion of Zingiber officinale Extract and Evaluation of Stability as a First Step to Determine its Bioaccesibility

A. Faccini, C. Falavigna, Marco Pieroni, 2018, Natural Product Communications.