N. Fernández

发表

Biased agonism at histamine H1 receptor: desensitization, internalization and MAPK activation triggered by antihistamines.

C. Shayo, C. Davio, C. Zappia, 2021, European journal of pharmacology.

Hexachlorobenzene modulates the crosstalk between the aryl hydrocarbon receptor and transforming growth factor-β1 signaling, enhancing human breast cancer cell migration and invasion.

A. Carozzo, C. Cocca, N. Miret, 2016, Toxicology.

Expression of a G Protein-coupled Receptor (GPCR) Leads to Attenuation of Signaling by Other GPCRs

S. Copsel, C. Shayo, C. Davio, 2010, The Journal of Biological Chemistry.

Tiotidine, a histamine H2 receptor inverse agonist that binds with high affinity to an inactive G-protein-coupled form of the receptor. Experimental support for the cubic ternary complex model.

C. Shayo, C. Davio, M. Riveiro, 2003, Molecular pharmacology.

Antihistamines Potentiate Dexamethasone Anti-Inflammatory Effects. Impact on Glucocorticoid Receptor-Mediated Expression of Inflammation-Related Genes

C. Zappia, F. Monczor, C. Fitzsimons, 2021, Cells.

Oligodendrocyte differentiation and signaling after transferrin internalization: A mechanism of action

Maria J Perez, J. Pasquini, N. Fernández, 2013, Experimental Neurology.

Roles of Phosphorylation-dependent and -independent Mechanisms in the Regulation of Histamine H2 Receptor by G Protein-coupled Receptor Kinase 2*

C. Shayo, C. Davio, F. Monczor, 2011, The Journal of Biological Chemistry.

The Regulator of G Protein Signaling Homologous Domain of G Protein-Coupled Receptor Kinase 2 Mediates Short-Term Desensitization of β3-Adrenergic Receptor

C. Shayo, C. Davio, F. Monczor, 2020, Frontiers in Pharmacology.

The time-course of cyclic AMP signaling is critical for leukemia U-937 cell differentiation.

C. Shayo, C. Davio, M. Riveiro, 2004, Biochemical and biophysical research communications.

Physiological implications of biased signaling at histamine H2 receptors

C. Shayo, C. Davio, C. Zappia, 2015, Front. Pharmacol..

Lipid Goals in Diabetic Patients. Clinical Implications after Application of a New Formula for LDL-cholesterol Calculation

M. Lobo, G. Molinero, G. Masson, 2020 .

Involvement of histamine H1 and H2 receptor inverse agonists in receptor's crossregulation

C. Shayo, C. Davio, C. Zappia, 2019, European journal of pharmacology.

Participation of Gαi-Adenylate Cyclase and ERK1/2 in Mas Receptor Signaling Pathways

F. Dominici, C. Davio, M. Muñoz, 2019, Front. Pharmacol..

Rapid desensitization and slow recovery of the cyclic AMP response mediated by histamine H(2) receptors in the U937 cell line.

C. Shayo, C. Davio, F. Monczor, 2000, Biochemical pharmacology.

Cross-Desensitization and Cointernalization of H1 and H2 Histamine Receptors Reveal New Insights into Histamine Signal Integration

J. Gutkind, C. Notcovich, C. Shayo, 2013, Molecular Pharmacology.

Antihistaminergics and inverse agonism: potential therapeutic applications.

C. Shayo, C. Davio, F. Monczor, 2013, European journal of pharmacology.

Histamine H2 Receptor Trafficking: Role of Arrestin, Dynamin, and Clathrin in Histamine H2 Receptor Internalization

C. Shayo, C. Davio, F. Monczor, 2008, Molecular Pharmacology.

Histamine H 2 Receptor Trafficking : Role of Arrestin , Dynamin , and Clathrin in Histamine H 2 Receptor Internalization

C. Shayo, C. Davio, F. Monczor, 2008 .

Reduction of G protein-coupled receptor kinase 2 expression in U-937 cells attenuates H2 histamine receptor desensitization and induces cell maturation.

C. Notcovich, C. Shayo, C. Davio, 2002, Molecular pharmacology.

Histamine H2 receptor desensitization: involvement of a select array of G protein-coupled receptor kinases.

C. Shayo, C. Davio, F. Monczor, 2001, Molecular pharmacology.

Validation of commercial Mas receptor antibodies for utilization in Western Blotting, immunofluorescence and immunohistochemistry studies

R. Santos, F. Dominici, M. Bader, 2017, PloS one.

G2/M Cell Cycle Arrest and Tumor Selective Apoptosis of Acute Leukemia Cells by a Promising Benzophenone Thiosemicarbazone Compound

C. Shayo, C. Davio, F. Remes Lenicov, 2015, PloS one.

Histamine H2 receptor overexpression induces U937 cell differentiation despite triggered mechanisms to attenuate cAMP signalling.

C. Shayo, C. Davio, F. Monczor, 2006, Biochemical pharmacology.

Mepyramine, a Histamine H1 Receptor Inverse Agonist, Binds Preferentially to a G Protein-coupled Form of the Receptor and Sequesters G Protein*

C. Shayo, C. Davio, F. Monczor, 2004, Journal of Biological Chemistry.

Identification of inhibitors of the RGS homology domain of GRK2 by docking-based virtual screening.

Ezequiel I. Juritz, C. Davio, P. L. Menna, 2019, Life sciences.

Current Knowledge and Perspectives on Histamine H1 and H2 Receptor Pharmacology: Functional Selectivity, Receptor Crosstalk, and Repositioning of Classic Histaminergic Ligands

F. Monczor, N. Fernández, 2016, Molecular Pharmacology.

Histamine H2 Receptor in Blood Cells: A Suitable Target for the Treatment of Acute Myeloid Leukemia.

S. Copsel, C. Shayo, C. Davio, 2016, Handbook of experimental pharmacology.

Regulatory mechanisms underlying GKR2 levels in U937 cells: evidence for GRK3 involvement.

C. Shayo, C. Davio, F. Monczor, 2007, Biochemical pharmacology.

Pharmacological Rac1 inhibitors with selective apoptotic activity in human acute leukemic cell lines

C. Davio, G. Cardama, N. González, 2017, Oncotarget.

Effects of histamine H1 receptor signaling on glucocorticoid receptor activity. Role of canonical and non-canonical pathways

C. Shayo, C. Davio, C. Zappia, 2015, Scientific Reports.

MRP4/ABCC4 expression is regulated by histamine in acute myeloid leukemia cells, determining cAMP efflux

C. Shayo, C. Davio, F. Monczor, 2020, The FEBS journal.

Dual Role of cAMP in the Transcriptional Regulation of Multidrug Resistance-Associated Protein 4 (MRP4) in Pancreatic Adenocarcinoma Cell Lines

C. Shayo, C. Davio, A. Carozzo, 2015, PloS one.

AT1 receptor blockade delays postlactational mammary gland involution: a novel role for the renin angiotensin system

T. Walther, J. Geffner, K. Nahmod, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Signal transduction mechanism of biased ligands at histamine H2 receptors.

C. Shayo, C. Davio, F. Monczor, 2014, The Biochemical journal.

PI3K pathway is involved in ERK signaling cascade activation by histamine H2R agonist in HEK293T cells.

J. Gutkind, C. Shayo, C. Davio, 2016, Biochimica et biophysica acta.

Azelastine potentiates antiasthmatic dexamethasone effect on a murine asthma model

C. Shayo, C. Davio, C. Zappia, 2019, Pharmacology research & perspectives.

Cross-Desensitization and Cointernalization of H1 and H2 Histamine Receptors Reveal New Insights into Histamine Signal Integration

C. Notcovich, C. Shayo, C. Davio, 2013, Molecular Pharmacology.

Antihistaminergics and inverse agonism: potential therapeutic applications.

C. Shayo, C. Davio, F. Monczor, 2013, European journal of pharmacology.