O. Sanz

发表

Novel Antitubercular 6-Dialkylaminopyrimidine Carboxamides from Phenotypic Whole-Cell High Throughput Screening of a SoftFocus Library: Structure–Activity Relationship and Target Identification Studies

G. Drewes, C. Harris, Markus Boesche, 2017, Journal of medicinal chemistry.

GSK2556286 Is a Novel Antitubercular Drug Candidate Effective In Vivo with the Potential To Shorten Tuberculosis Treatment

Robert H Bates, N. Fotouhi, G. Besra, 2022, bioRxiv.

1,3-Diarylpyrazolyl-acylsulfonamides Target HadAB/BC Complex in Mycobacterium tuberculosis

G. Drewes, M. Bantscheff, K. Chibale, 2022, ACS infectious diseases.

A multipass membrane protein interacts with the cGMP-dependent protein kinase to regulate critical calcium signals in malaria parasites

S. Howell, M. Bantscheff, C. Withers-Martinez, 2020, bioRxiv.

Ca2+ signals critical for egress and gametogenesis in malaria parasites depend on a multipass membrane protein that interacts with PKG

S. Howell, M. Bantscheff, C. Withers-Martinez, 2021, Science Advances.

Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity

E. Winzeler, M. Bösche, K. Chibale, 2020, Cell chemical biology.

The multi-target aspect of an MmpL3 inhibitor: The BM212 series of compounds bind EthR2, a transcriptional regulator of ethionamide activation

M. Bantscheff, G. Besra, J. Lelièvre, 2021, The Cell Surface.

Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis.

Thomas R. Ioerger, Travis Hartman, Tom L. Blundell, 2017, ACS infectious diseases.

Cyclic AMP-Mediated Inhibition of Cholesterol Catabolism in Mycobacterium tuberculosis by the Novel Drug Candidate GSK2556286

David Barros, B. VanderVen, L. Eltis, 2023, Antimicrobial agents and chemotherapy.