Matthew Britton

Nature of Pharmacophore Influences Active Site Specificity of Proteasome Inhibitors*

H. Overkleeft, B. Florea, M. Screen, 2010, The Journal of Biological Chemistry.

Specific cell-permeable inhibitor of proteasome trypsin-like sites selectively sensitizes myeloma cells to bortezomib and carfilzomib.

D. Filippov, H. Overkleeft, B. Florea, 2011, Chemistry & biology.

Selective inhibitor of proteasome's caspase-like sites sensitizes cells to specific inhibition of chymotrypsin-like sites.

Matthew Britton, Martijn Verdoes, H. Overkleeft, 2009, Chemistry & biology.