F. Moore

发表

Mcl-1 downregulation by pro-inflammatory cytokines and palmitate is an early event contributing to β-cell apoptosis

D. Eizirik, J. Vanderwinden, A. K. Cardozo, 2011, Cell Death and Differentiation.

The Transcription Factor C/EBP delta Has Anti-Apoptotic and Anti-Inflammatory Roles in Pancreatic Beta Cells

P. Marchetti, D. Eizirik, I. Santin, 2012, PloS one.

PTPN 2 , a candidate gene for type 1 diabetes , modulates interferon-gamma-induced pancreatic beta-cell apoptosis

M. Bugliani, P. Marchetti, D. Eizirik, 2009 .

PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma- induced pancreatic beta-cell apoptosis Running title: PTPN2 regulates cytokine-induced β-cell death.

M. Bugliani, P. Marchetti, D. Eizirik, 2009 .

PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Interferon-γ–Induced Pancreatic β-Cell Apoptosis

M. Bugliani, P. Marchetti, D. Eizirik, 2009, Diabetes.

Interferon regulatory factor-1 is a key transcription factor in murine beta cells under immune attack

D. Eizirik, C. Gysemans, L. Overbergh, 2009, Diabetologia.

Regulation and function of the cytosolic viral RNA sensor RIG-I in pancreatic beta cells.

G. Hartmann, Shintaro Sato, D. Eizirik, 2009, Biochimica et biophysica acta.

Induction of nuclear factor-κB and its downstream genes by TNF-α and IL-1β has a pro-apoptotic role in pancreatic beta cells

T. Ørntoft, E. Théâtre, D. Eizirik, 2008, Diabetologia.

Neutrophil‐dependent tumor rejection and priming of tumoricidal CD8+ T cell response induced by dendritic cells overexpressing CD95L

M. Goldman, V. Flamand, F. Paulart, 2008, Journal of leukocyte biology.

Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death

P. Marchetti, R. Planas, D. Eizirik, 2011, Diabetes.

Initiation and execution of lipotoxic ER stress in pancreatic β-cells

Tsonwin Hai, G. Rutter, P. Marchetti, 2008, Journal of Cell Science.

Cytokines Interleukin-1β and Tumor Necrosis Factor-α Regulate Different Transcriptional and Alternative Splicing Networks in Primary β-Cells

Torben F. Ørntoft, Najib Naamane, T. Ørntoft, 2009, Diabetes.

PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Pancreatic β-Cell Apoptosis via Regulation of the BH3-Only Protein Bim

P. Marchetti, D. Eizirik, I. Santin, 2011, Diabetes.

An Alternative Pathway of NF-κB Activation Results in Maturation and T Cell Priming Activity of Dendritic Cells Overexpressing a Mutated IκBα1

Michel Goldman, Kris Thielemans, Elena Lazarova, 2007, The Journal of Immunology.

Use of RNA interference to investigate cytokine signal transduction in pancreatic beta cells.

D. Eizirik, H. Mulder, D. Cunha, 2012, Methods in molecular biology.

STAT1 Is a Master Regulator of Pancreatic β-Cell Apoptosis and Islet Inflammation*

T. Ørntoft, Gianluca Bontempi, C. Mathieu, 2010, The Journal of Biological Chemistry.

Cytokines Tumor Necrosis Factor-α and Interferon-γ Induce Pancreatic β-Cell Apoptosis through STAT1-mediated Bim Protein Activation*

D. Drucker, P. Marchetti, C. Mathieu, 2011, The Journal of Biological Chemistry.

Critical Influence of Natural Regulatory CD25+ T Cells on the Fate of Allografts in the Absence of Immunosuppression

M. Goldman, H. Waldmann, L. Graça, 2005, Transplantation.

IL-17A increases the expression of proinflammatory chemokines in human pancreatic islets

P. Marchetti, C. Mathieu, I. Santin, 2014, Diabetologia.

USP18 is a key regulator of the interferon-driven gene network modulating pancreatic beta cell inflammation and apoptosis

P. Marchetti, I. Santin, C. Brancolini, 2012, Cell Death and Disease.

siRNA‐mediated knock‐down of ZnT3 and ZnT8 affects production and secretion of insulin and apoptosis in INS‐1E cells

K. Smidt, J. Rungby, N. Magnusson, 2011, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

Nicotine Protects Kidney from Renal Ischemia/Reperfusion Injury through the Cholinergic Anti-Inflammatory Pathway

M. Goldman, S. Florquin, A. Le Moine, 2007, PloS one.

An alternative pathway of NF-kappaB activation results in maturation and T cell priming activity of dendritic cells overexpressing a mutated IkappaBalpha.

M. Goldman, V. Flamand, F. Paulart, 2007, Journal of immunology.

Central role and mechanisms of β‐cell dysfunction and death in friedreich ataxia–associated diabetes

A. Koeppen, C. Depondt, M. Pandolfo, 2012, Annals of neurology.

Use of a systems biology approach to understand pancreatic beta-cell death in Type 1 diabetes.

D. Eizirik, F. Ortis, D. Flamez, 2008, Biochemical Society transactions.

MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic β-cell responses to the viral by-product double-stranded RNA

D. Eizirik, F. Ortis, M. Colli, 2009, Human molecular genetics.

PTPN2 and MDA5, two candidate genes for type 1 diabetes, modify beta cell responses to double-stranded RNA

D. Eizirik, F. Ortis, M. Colli, 2009 .

TUMOR NECROSIS FACTOR- α AND INTERFERON- γ INDUCE PANCREATIC β -CELL APOPTOSIS THROUGH STAT1-MEDIATED BIM ACTIVATION

D. Drucker, P. Marchetti, C. Mathieu, 2011 .

siRNA‐mediated knock‐down of ZnT3 and ZnT8 affects production and secretion of insulin and apoptosis in INS‐1E cells

K. Smidt, J. Rungby, N. Magnusson, 2011, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

Use of a systems biology approach to understand pancreatic beta-cell death in Type 1 diabetes.

D. Eizirik, F. Ortis, D. Flamez, 2008, Biochemical Society transactions.

Unexpected effects of viral interleukin-10-secreting dendritic cells in vivo: preferential inhibition of TH2 responses.

M. Goldman, V. Flamand, F. Paulart, 2004, Transplantation proceedings.