C. Marchioro

发表

Novel stereocontrolled addition of allylmetal reagents to alpha-imino esters: efficient synthesis of chiral tetrahydroquinoline derivatives.

S. Lynn, D. Donati, Barbara Bertani, 2002, The Journal of organic chemistry.

Magnetic resonance spectroscopy investigations of brown adipose tissue and isolated brown adipocytes.

C. Zancanaro, A. Sbarbati, F. Osculati, 1994, Journal of lipid research.

Synthesis and pharmacological characterization of novel druglike corticotropin-releasing factor 1 antagonists.

A. Capelli, F. Blaney, S. Provera, 2008, Journal of medicinal chemistry.

Synthesis and structure-activity relationship of new 1,5-dialkyl-1,5-benzodiazepines as cholecystokinin-2 receptor antagonists.

G. Tedesco, A. Reggiani, R. Barnaby, 2011, Bioorganic & medicinal chemistry.

Discovery process and pharmacological characterization of a novel dual orexin 1 and orexin 2 receptor antagonist useful for treatment of sleep disorders.

K. Thewlis, E. Chiarparin, Christopher N. Johnson, 2011, Bioorganic & medicinal chemistry letters.

A novel ketolide class: Synthesis and antibacterial activity of a lead compound.

S. Lociuro, A. Pozzan, E. Ratti, 2007, Bioorganic & medicinal chemistry letters.

Application of LC–NMR to the identification of bulk drug impurities in NK1 antagonist GW597599 (vestipitant)

S. Provera, G. Guercio, O. Curcuruto, 2010, Magnetic resonance in chemistry : MRC.

Towards the Discovery of New Hypnotic Agents: Synthesis and Preliminary Pharmacological Evaluation of a Novel Class of Dibenzo[a,d]cycloheptene Derivatives

M. Wigglesworth, M. Botta, M. Gianotti, 2010, ChemMedChem.

Identification, biological characterization and pharmacophoric analysis of a new potent and selective NK1 receptor antagonist clinical candidate.

Michael K. Trower, R. Carletti, S. Melotto, 2013, Bioorganic & medicinal chemistry.

Discovery and biological characterization of (2R,4S)-1'-acetyl-N-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl}-2-(4-fluoro-2-methylphenyl)-N-methyl-4,4'-bipiperidine-1-carboxamide as a new potent and selective neurokinin 1 (NK1) receptor antagonist clinical candidate.

S. Melotto, M. Corsi, D. Montanari, 2011, Journal of medicinal chemistry.

Benzoazepine derivative as potent antagonists of the glycine binding site associated to the NMDA receptor.

S. Provera, D. Donati, F. Micheli, 2003, Farmaco.

Discovery process and pharmacological characterization of 2-(S)-(4-fluoro-2-methylphenyl)piperazine-1-carboxylic acid [1-(R)-(3,5-bis-trifluoromethylphenyl)ethyl]methylamide (vestipitant) as a potent, selective, and orally active NK1 receptor antagonist.

S. Melotto, M. Corsi, D. Montanari, 2009, Journal of medicinal chemistry.

Detection, identification and quantification of a new de-fluorinated impurity in casopitant mesylate drug substance during late phase development: an analytical challenge involving a multidisciplinary approach.

S. Provera, R. Dams, D. Castoldi, 2011, Journal of pharmaceutical and biomedical analysis.

Triazolyl Azabicyclo[3.1.0]hexanes: a Class of Potent and Selective Dopamine D3 Receptor Antagonists

A. Capelli, G. Tedesco, A. Worby, 2010, ChemMedChem.

Synthesis of a novel fluoro-tribactam utilising an N-fluorosulfonimide in the key step

Alessandro Padova, S. Roberts, D. Donati, 1996 .

Synthesis of a novel fluoro-tribactam utilising N-fluorosulfommide in the key step

Alessandro Padova, S. Roberts, D. Donati, 1995 .

Stereoselective Synthesis of a Key Intermediate of Sanfetrinem by Means of a Chelated Tin(IV) Enolate

A. Paio, P. Zarantonello, T. Rossi, 1997 .

NOVEL AMIDOALKYLATION OF 4-ACETOXYAZETIDINONES WITH ALLYLIC BORANES. A STEREOSELECTIVE ENTRY INTO THE TRIBACTAMS

T. Rossi, C. Marchioro, S. Biondi, 1995 .

Synthesis and antimicrobial activity of DNA-gyrase inhibiting derivatives of 4-oxo-1,4-dihydro-3-pyridinecarboxylic acid.

G. Gaviraghi, G. Tarzia, A. Feriani, 1993, Il Farmaco.

HIGHLY STEREOCONTROLLED SYNTHESIS OF ENANTIOMERIC 4-METHOXY TRINEMS VIA RESOLUTION OF SCALEMIC ENOL PHOSPHATES

R. Camerini, D. Donati, M. Panunzio, 1996 .

Synthesis and antibacterial activity of 4- and 8-methoxy trinems

G. Gaviraghi, E. D. Modugno, D. Donati, 1996 .

Synthesis and NMR studies of key intermediates to a new class ofβ-lactam: the trinems

D. Donati, C. Marchioro, G. Pentassuglia, 1997 .

Novel Amidoalkylation of 4-Acetoxyazetidinones with Allylic Boranes. A Stereoselective Entry into the Tribactams.

T. Rossi, C. Marchioro, S. Biondi, 1996 .

Synthesis of esters of the potent anti-bacterial trinems and analogues

S. Roberts, D. Donati, T. Rossi, 1996 .

Iodine‐Mediated Cyclization of (4R,5R)‐4,5‐Diamino‐N,N′‐bis[(1S)‐1‐phenylethyl]‐1,7‐octadiene – A Stereoselective Route to 2,5‐Diazabicyclo[2.2.1]heptanes

G. Martelli, M. Monari, D. Savoia, 2005 .

Lipase-catalysed resolution of cis-1-ethoxycarbonyl-2-hydroxy-cyclohexane: Enantioselective total synthesis of 10-ethyl-trinem

R. Camerini, D. Donati, M. Panunzio, 1997 .

Synthesis of 6-methoxy-6a-hydroxymethylpenems

G. Tarzia, R. Pellicciari, B. Sadeghpour, 1995 .

Substituted Indole‐2‐carboxylates as Potent Antagonists of the Glycine Binding Site Associated with the NMDA Receptor

M. Mugnaini, F. Micheli, R. Di Fabio, 1999, Archiv der Pharmazie.

5- and 7-oxa trinems: their synthesis and biological evaluation

T. Rossi, C. Marchioro, D. Andreotti, 1996 .

Highly Stereocontrolled Synthesis of Enantiomeric 4-Methoxy Trinems via Resolution of Scalemic Enol Phosphates.

R. Camerini, D. Donati, M. Panunzio, 1997 .

Synthesis and enantiomeric excess determination of (6S)-1-(trimethylsilyloxy)-6-(N-methyl-N-benzyloxycarbonylamino)-cyclohexene

L. Rossi, C. Marchioro, M. Maffeis, 1997 .

Synthesis and Antibacterial Activity of 4‐ and 8‐Methoxy Trinems.

G. Gaviraghi, E. D. Modugno, D. Donati, 1996 .

Synthesis and NMR Studies of Key Intermediates to a New Class of β -Lactam: The Trinems.

D. Donati, C. Marchioro, G. Pentassuglia, 1997 .

Synthesis of Esters of the Potent Antibacterial Trinems and Analogues.

S. Roberts, D. Donati, T. Rossi, 1997 .

Self-induced diastereoselective oxidation of vinyl sulfoxides bearing a chiral hydroxy group as a way of preparation of optically active sulfinyl dienophiles and their use in the asymmetric Diels-Alder reactions to cyclopentadiene

V. Lucchini, G. Valle, O. Lucchi, 1986 .

Application of LC-NMR and HR-NMR to the characterization of biphenyl impurities in the synthetic route development for vestipitant, a novel NK1 antagonist.

S. Provera, G. Guercio, Luca Martini, 2010, Journal of pharmaceutical and biomedical analysis.

Design, synthesis, and biological evaluation of novel aminobisphosphonates possessing an in vivo antitumor activity through a gammadelta-T lymphocytes-mediated activation mechanism.

E. Novellino, N. Gebbia, F. Dieli, 2008, Journal of medicinal chemistry.

Asymmetric Diels–Alder reactions of sulphinyl-activated dienophiles obtained via a self-induced chiral oxidation

G. Valle, O. Lucchi, G. Modena, 1985 .

NMR spectroscopy and surface tension measurements applied to the study of self-association of casopitant mesylate, a novel NK1 antagonist.

S. Provera, S. Beato, Zadeo Cimarosti, 2011, Journal of pharmaceutical and biomedical analysis.

d‐Glucose as a Regioselectively Addressable Scaffold for Combinatorial Chemistry on Solid Phase

F. Nicotra, P. Seneci, F. Peri, 2003 .

Long‐range two‐dimensional 1H–29Si heteronuclear shift correlation using gradients. Application to tetra‐TMS‐α‐O‐methyl‐D‐glucopyranose and tetra‐TES‐α‐O‐methyl‐D‐glucopyranose

S. Provera, G. Raza, S. Davalli, 2001 .

Asymmetric synthesis of some substituted-3-phenyl prolines.

F. Micheli, R. Di Fabio, C. Marchioro, 1999, Farmaco.

Analytical methods for the monitoring of solid phase organic synthesis.

S. Provera, A. Zaramella, M. Passarini, 2002, Farmaco.

Synthesis of 6β-methoxy-6α-hydroxymethylpenems

G. Tarzia, R. Pellicciari, B. Sadeghpour, 1995 .

Polymer-supported silyl cyanide and silyl azide: useful reagents for solid-phase applications.

P. Seneci, M. Panunzio, T. Rossi, 2000, Biotechnology and bioengineering.

From pyrroles to pyrrolo[1,2-a]pyrazinones: a new class of mGluR1 antagonists.

D. Donati, F. Micheli, P. Cavanni, 2006, Bioorganic & medicinal chemistry letters.

In vivo metabolism of a novel cholecystokinin B (CCK-B) antagonist in rat and dog plasma and rat faeces.

M. Kajbaf, M. Pellegatti, C. Marchioro, 1998, Xenobiotica; the fate of foreign compounds in biological systems.

Letter to the Editor: Backbone 1H, 13C and 15N resonance assignment of the N-terminal 24 kDa fragment of the gyrase B subunit from E. coli

E. Domenici, J. Weigelt, G. Otting, 2002, Journal of Biomolecular NMR.

Conformationally constrained tryptophan analogs. Synthesis of (±)-(Z)- and (±)-(E)-2-amino-2,3-methano-3-(indol-3-yl)-propanoic acids

B. Natalini, R. Pellicciari, D. Donati, 1996 .

1-(Aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes and 6-(aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes: a new series of potent and selective triple reuptake inhibitors.

K. Read, G. Tedesco, D. Minick, 2010, Journal of medicinal chemistry.

1-Heteroaryl-6-(3,4-dichlorophenyl)-3-azabicyclo[4.1.0]heptane: further insights into a class of triple re-uptake inhibitors.

M. Roščić, A. Worby, F. Micheli, 2011, Bioorganic & medicinal chemistry.

6-(3,4-dichlorophenyl)-1-[(methyloxy)methyl]-3-azabicyclo[4.1.0]heptane: a new potent and selective triple reuptake inhibitor.

K. Read, G. Tedesco, R. Carletti, 2010, Journal of medicinal chemistry.

Cycloalkyl Indole‐2‐Carboxylates as Useful Tools for Mapping the "North‐Eastern" Region of the Glycine Binding Site Associated with the NMDA Receptor

A. Capelli, F. Micheli, R. Di Fabio, 1999, Archiv der Pharmazie.

2,4-Dicarboxy-pyrroles as selective non-competitive mGluR1 antagonists: an exploration of the role of the pyrrolic scaffold.

G. Tarzia, D. Donati, F. Micheli, 2003, Farmaco.

A multi-technique approach using LC-NMR, LC-MS, semi-preparative HPLC, HR-NMR and HR-MS for the isolation and characterization of low-level unknown impurities in GW876008, a novel corticotropin-release factor 1 antagonist.

S. Provera, A. Ribecai, L. Rovatti, 2010, Journal of pharmaceutical and biomedical analysis.

Backbone 1H, 13C and 15N resonance assignment of the N-terminal 24 kDa fragment of the gyrase B subunit from E. coli.

E. Domenici, J. Weigelt, G. Otting, 2002, Journal of Biomolecular NMR.

1,2,4-Triazolyl azabicyclo[3.1.0]hexanes: a new series of potent and selective dopamine D(3) receptor antagonists.

A. Capelli, G. Tedesco, F. Blaney, 2010, Journal of medicinal chemistry.

Fruitful adrenergic α(2C)-agonism/α(2A)-antagonism combination to prevent and contrast morphine tolerance and dependence.

U. Zanelli, L. Mattioli, M. Giannella, 2010, Journal of medicinal chemistry.

Application of LC–NMR to the identification of bulk drug impurities in NK1 antagonist GW597599 (vestipitant)

S. Provera, G. Guercio, O. Curcuruto, 2010, Magnetic resonance in chemistry : MRC.