L. Rokosz

发表

Discovery of novel quinolinone adenosine A2B antagonists.

A. Klon, M. Webb, V. Srivastava, 2010, Bioorganic & medicinal chemistry letters.

Discovery and preliminary evaluation of 5-(4-phenylbenzyl)oxazole-4-carboxamides as prostacyclin receptor antagonists.

D. Auld, M. Webb, I. Henderson, 2007, Bioorganic & medicinal chemistry letters.

Surfing the piperazine core of tricyclic farnesyltransferase inhibitors.

N. Sigal, J. Reader, J. Baldwin, 2005, Bioorganic & medicinal chemistry letters.

Farnesyltransferase inhibitors: recent advances

Chia‐Yu Huang, L. Rokosz, 2004 .

Regulation of calcineurin phosphatase activity and interaction with the FK-506.FK-506 binding protein complex.

R. Kincaid, S. O'keefe, G. Wiederrecht, 1994, The Journal of biological chemistry.

Human cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A synthase: expression, purification, and characterization of recombinant wild-type and Cys129 mutant enzymes.

J. Hermes, G. Sanyal, P. Lachance, 1994, Archives of biochemistry and biophysics.

Reconstitution of active human calcineurin from recombinant subunits expressed in bacteria.

S. O'keefe, J. Burbaum, P. Cameron, 1995, Protein expression and purification.

Use of an Active-Site Inhibitor of Stromelysin to Elucidate the Mechanism of Prostromelysin Activation

J. Hermes, P. Cameron, A. Marcy, 1995 .

Synthesis and structure-activity relationships of new disubstituted phenyl-containing 3,4-diamino-3-cyclobutene-1,2-diones as CXCR2 receptor antagonists.

M. Czarniecki, D. Rindgen, Tara M Stauffer, 2008, Bioorganic & medicinal chemistry letters.

Pitfalls of fad diets and weight loss drugs

L. Rokosz, 2014 .

Synthesis of 2-amino-5-benzoyl-4-(2-furyl)thiazoles as adenosine A(2A) receptor antagonists.

A. Metzger, L. W. Dillard, I. Henderson, 2009, Bioorganic & medicinal chemistry letters.

Synthesis and structure-activity relationships of 3,4-diaminocyclobut-3-ene-1,2-dione CXCR2 antagonists.

M. Dwyer, J. Baldwin, L. Ozgur, 2006, Bioorganic & medicinal chemistry letters.

Discovery of 2-hydroxy-N,N-dimethyl-3-{2-[[(R)-1-(5- methylfuran-2-yl)propyl]amino]-3,4-dioxocyclobut-1-enylamino}benzamide (SCH 527123): a potent, orally bioavailable CXCR2/CXCR1 receptor antagonist.

M. Dwyer, J. Baldwin, L. Ozgur, 2006, Journal of medicinal chemistry.

Synthesis and SAR studies of trisubstituted purinones as potent and selective adenosine A2A receptor antagonists.

I. Henderson, Tara M Stauffer, B. Mcguinness, 2009, Bioorganic & medicinal chemistry letters.

Guiding farnesyltransferase inhibitors from an ECLiPS library to the catalytic zinc.

R. Doll, J. Reader, J. Baldwin, 2006, Bioorganic & medicinal chemistry letters.

Kinase inhibitors as drugs for chronic inflammatory and immunological diseases: progress and challenges

Maria L Webb, M. Webb, C. Carroll, 2008 .

Discovery and SAR of 4-amino-2-biarylbutylurea MCH 1 receptor antagonists through solid-phase parallel synthesis.

T. Guo, D. Hobbs, Tao Guo, 2005, Bioorganic & medicinal chemistry letters.

Discovery and development of melanin-concentrating hormone receptor 1 antagonists for the treatment of obesity

L. Rokosz, 2007, Expert opinion on drug discovery.

Stromelysin‐1: Three‐dimensional structure of the inhibited catalytic domain and of the C‐truncated proenzyme

J. Springer, J. Hermes, P. Fitzgerald, 1995, Protein science : a publication of the Protein Society.

Binary encoded small-molecule libraries in drug discovery and optimization

N. Sigal, J. Reader, J. Baldwin, 1995 .

Discovery of 2-aminoimidazopyridine adenosine A(2A) receptor antagonists.

I. Henderson, Tara M Stauffer, Guizhen Dong, 2010, Bioorganic & medicinal chemistry letters.

Discovery and SAR of biaryl piperidine MCH1 receptor antagonists through solid-phase encoded combinatorial synthesis.

S. Babu, T. Guo, D. Hobbs, 2005, Bioorganic & medicinal chemistry letters.

Biological examination of melanin concentrating hormone receptor 1: multi-tasking from the hypothalamus.

D. Hobbs, L. Rokosz, 2006, Drug News and Perspectives.

Discovery of tetralin ureas as potent melanin concentrating hormone 1 receptor antagonists.

T. Guo, D. Hobbs, D. Busler, 2007, Bioorganic & medicinal chemistry letters.

Kinase inhibitors as drugs for chronic inflammatory and immunological diseases: progress and challenges.

M. Webb, C. Carroll, K. Appell, 2008, Expert opinion on therapeutic targets.