M. Duflos

发表

Efficient New Synthesis of N-Arylbenzo[b]furo[3,2-d]pyrimidin-4-amines and Their Benzo[b]thieno[3,2-d]pyrimidin-4-amine Analogues via a Microwave-Assisted Dimroth Rearrangement

C. Corbière, T. Besson, P. Marchand, 2013 .

Discovery of a novel broad-spectrum antifungal agent derived from albaconazole.

P. Le Pape, T. Besson, C. Logé, 2013, ACS medicinal chemistry letters.

First synthesis of 4-aminopyrido[2′,3′:4,5]furo[3,2-d]pyrimidines

T. Besson, P. Marchand, Yvonnick Loidreau, 2012 .

Synthesis and biological evaluation of N-arylbenzo[b]thieno[3,2-d]pyrimidin-4-amines and their pyrido and pyrazino analogues as Ser/Thr kinase inhibitors.

L. Meijer, O. Lozach, N. Loaëc, 2012, European journal of medicinal chemistry.

A Novel Indole-3-propanamide Exerts Its Immunosuppressive Activity by Inhibiting JAK3 in T Cells

P. Marchand, C. Chauvet, J. Petit, 2009, Journal of Pharmacology and Experimental Therapeutics.

Synthesis and hypolipidemic activity of N-pyridinyl borodipeptidylamides

J. Robert, F. Mainard, M. Duflos, 1994 .

A convenient synthesis of 5-arylamino-4H-pyran-4-ones using palladium-catalyzed amination

B. Pfeiffer, C. Logé, B. Lesur, 2009 .

6-Amino-2,4-lutidine carboxamides: α-aminoamide derivatives as systemic and topical inflammation inhibitors

P. Renard, D. Caignard, M. Duflos, 1998 .

N-pyridinyl-indole-3-(alkyl)carboxamides and derivatives as potential systemic and topical inflammation inhibitors.

J. Petit, M. Nourrisson, M. Duflos, 2001, European journal of medicinal chemistry.

Synthesis and anti-inflammatory activity of N-(aza)arylcarboxamides derived from Trolox®

P. Renard, D. Caignard, M. Duflos, 1998 .

Efficient one-pot synthesis of 3,7-disubstituted 1,6-naphthyridin-2(1H)-ones through regioselective palladium-catalyzed cross-coupling and SNAr reactions

M. Bazin, M. Duflos, Alain Tonnerre, 2015 .

Indole carboxamides inhibit bovine testes hyaluronidase at pH 7.0 and indole acetamides activate the enzyme at pH 3.5 by different mechanisms

J. Jose, Andre Kaessler, M. Nourrisson, 2008 .

A convenient route to functionalized 3-amino-6-bromofuro[3,2-b]pyridine-2-carboxamides

P. Marchand, G. D. Nanteuil, M. Nourrisson, 2010 .

Novel approach towards 3,7-disubstituted 1,6-naphthyridin-4(1H)-ones exploiting cross-coupling and SNAr reactions of a dihalogenated compound

J. Robert, M. Bazin, M. Duflos, 2018, Tetrahedron Letters.

The Marine-Derived Fungus Clonostachys rosea, Source of a Rare Conjugated 4-Me-6E,8E-hexadecadienoic Acid Reducing Viability of MCF-7 Breast Cancer Cells and Gene Expression of Lipogenic Enzymes

G. Wielgosz-Collin, S. Bertrand, Nicolas Ruiz, 2015, Marine drugs.

Design, Synthesis, and Biological Evaluation of 1‐[(Biarylmethyl)methylamino]‐2‐(2,4‐difluorophenyl)‐3‐(1H‐1,2,4‐triazol‐1‐yl)propan‐2‐ols as Potent Antifungal Agents: New Insights into Structure–Activity Relationships

C. Logé, F. Pagniez, Rémi Guillon, 2011, ChemMedChem.

Synthesis of N‐Pyridinyl(methyl)‐1,2‐dihydro‐4‐hydroxy‐2‐oxoquinoline‐3‐carboxamides and analogues and their anti‐inflammatory activity in mice and rats

J. Robert, J. Petit, F. Lang, 2001, The Journal of pharmacy and pharmacology.

New N-pyridinyl(methyl)-indolalkanamides acting as topical inflammation inhibitors.

G. Le Baut, J. Petit, M. Duflos, 2004, Bioorganic & medicinal chemistry letters.

Synthesis and antifungal activities of new fluconazole analogues with azaheterocycle moiety.

P. Le Pape, M. Le Borgne, F. Pagniez, 2007, Bioorganic & medicinal chemistry letters.

New N -pyridinyl(methyl)-indole-2- and 3-(Alkyl)carboxamides and Derivatives Acting as Systemic and Topical Inflammation Inhibitors

G. Le Baut, J. Petit, M. Nourrisson, 2002, Journal of enzyme inhibition and medicinal chemistry.

Design, Synthesis, and in vitro Antifungal Activity of 1‐[(4‐Substituted‐benzyl)methylamino]‐2‐(2,4‐difluorophenyl)‐3‐(1H‐1,2,4‐triazol‐1‐yl)propan‐2‐ols

F. Morio, C. Logé, F. Pagniez, 2011, ChemMedChem.

Synthesis and in vitro antifungal evaluation of 2-(2,4-difluorophenyl)-1-[(1H-indol-3-ylmethyl)methylamino]-3-(1H-1,2,4-triazol-1-yl)propan-2-ols

V. Ferchaud-Roucher, C. Logé, F. Pagniez, 2011, Journal of enzyme inhibition and medicinal chemistry.

N-Pyridinyl(methyl)-indole-1- or 3-propanamides and propenamides acting as topical and systemic inflammation inhibitors

G. Le Baut, J. Petit, M. Nourrisson, 2008 .

3‐(Azolylmethyl)‐1H‐indoles as Selective P450 Aromatase Inhibitors

R. Hartmann, M. Ahmadi, P. Marchand, 1998 .

Synthesis and In Vitro Evaluation of 3‐(1‐Azolylmethyl)‐1H‐indoles and 3‐(1‐Azolyl‐1‐phenylmethyl)‐1H‐indoles as Inhibitors of P450 arom

R. Hartmann, P. Marchand, M. Duflos, 1997, Archiv der Pharmazie.

Design, synthesis and evaluation of new 6-substituted-5-benzyloxy-4-oxo-4H-pyran-2-carboxamides as potential Src inhibitors

B. Pfeiffer, C. Logé, F. Cruzalegui, 2008 .

Synthesis and biological evaluation of 5-[(aryl)(1H-imidazol-1-yl)methyl]-1H-indoles: potent and selective aromatase inhibitors.

Anja Palusczak, Rolf W Hartmann, R. Hartmann, 2006, Bioorganic & medicinal chemistry letters.

Non-acidic antiinflammatory compounds II. Synthesis and activity of 6-amino-2,4-lutidine derivatives

J. Robert, J. Petit, M. Duflos, 1994 .

Synthesis and biological evaluation of N-aryl-7-methoxybenzo[b]furo[3,2-d]pyrimidin-4-amines and their N-arylbenzo[b]thieno[3,2-d]pyrimidin-4-amine analogues as dual inhibitors of CLK1 and DYRK1A kinases.

L. Meijer, N. Loaëc, T. Besson, 2013, European journal of medicinal chemistry.

Synthesis of 1-benzyl-8,9-dihydroimidazo[4,5-c]pyrrolo[3,2-g]quinolin-4(5H)-one via palladium-catalyzed intramolecular arylation

P. Renard, B. Pfeiffer, P. Pinson, 2004 .

8-Amino-5-nitro-6-phenoxyquinolines: Potential Non-peptidic Neuropeptide Y Receptor Ligands

J. Boutin, P. Renard, P. Pinson, 2002, Journal of Enzyme Inhibition and Medicinal Chemistry.

Synthesis of N-aryl-3-(indol-3-yl)propanamides and their immunosuppressive activities.

F. Giraud, P. Marchand, F. Lang, 2010, Bioorganic & medicinal chemistry letters.

A Convenient Synthesis of 5‐Arylamino‐4H‐pyran‐4‐ones Using Palladium‐Catalyzed Amination.

B. Pfeiffer, C. Logé, B. Lesur, 2010 .

New N-(pyridin-4-yl)-(indol-3-yl)acetamides and propanamides as antiallergic agents.

J. Schmidt, I. Szelenyi, B. Nickel, 1999, Journal of medicinal chemistry.

Synthetic N-pyridinyl(methyl)-indol-3-ylpropanamides as new potential immunosuppressive agents.

J. Petit, F. Lang, D. Carbonnelle, 2007, European journal of medicinal chemistry.

Differential Functionalization of 1,6-Naphthyridin-2(1H)-ones through Sequential One-Pot Suzuki–Miyaura Cross-Couplings

M. Bazin, M. Duflos, Alain Tonnerre, 2014 .

Discovery of a novel broad-spectrum antifungal agent derived from albaconazole.

P. Le Pape, T. Besson, C. Logé, 2013, ACS medicinal chemistry letters.

Novel 1,6-naphthyridin-2(1H)-ones as potential anticancer agents targeting Hsp90.

S. Barillé-Nion, P. Juin, M. Bazin, 2016, European journal of medicinal chemistry.