Yunlei Hou

发表

Design, synthesis and antitumor activity of novel indolin-2-one derivatives containing 4-thiazolidinone moiety

N. Xu, P. Gong, Zijian Liu, 2015, Chemical Research in Chinese Universities.

Multigram-scale synthesis of GSK 2,256,294, an inhibitor of soluble epoxide hydrolase in clinical evaluation

Yanfang Zhao, Siyu Fu, Ye Tian, 2022, Chemical Papers.

Synthesis and biological evaluation of new series of benzamide derivatives containing urea moiety as sEH inhibitors

Yanping Sun, Xiaolu Su, Yanfang Zhao, 2022, Bioorganic & Medicinal Chemistry Letters.

Recent Advances in Metal‐Catalyzed Decarboxylative Reactions of Vinyl Benzoxazinanones

Jialu Liu, Yanfang Zhao, Siyu Fu, 2021, Advanced Synthesis & Catalysis.

Ligand-based optimization to identify novel 2-aminobenzo[d]thiazole derivatives as potent sEH inhibitors with anti-inflammatory effects.

Yanping Sun, P. Gong, Yanfang Zhao, 2020, European journal of medicinal chemistry.

Structural modifications of indolinones bearing a pyrrole moiety and discovery of a multi-kinase inhibitor with potent antitumor activity.

Haotian Zhang, Ye Tian, Mingze Qin, 2020, Bioorganic & medicinal chemistry.

Based on 2-(difluoromethyl)-1-[4,6-di(4-morpholinyl)-1,3,5-triazin-2-yl]-1H-benzimidazole (ZSTK474), design, synthesis and biological evaluation of novel PI3Kα selective inhibitors.

Yu Wang, Yanfang Zhao, Yajing Liu, 2022, Bioorganic chemistry.

Palladium-catalyzed three-component tandem reaction of sulfonyl hydrazones, aryl iodides and allenes: highly stereoselective synthesis of (Z)-α-hydroxymethyl allylic sulfones

P. Gong, Yanfang Zhao, Mingze Qin, 2017 .

Silver(I)‐ and Base‐Mediated formal [4+3] Cycloaddition of in Situ generated 1,2‐Diaza‐1,3‐dienes with C,N ‐Cyclic Azomethine Imines: An Efficient Protocol for the Synthesis of Tetrazepine Derivatives

P. Gong, Shuaikang Li, Yunlei Hou, 2020 .

Design, synthesis and biological evaluation of novel 7-amino-[1,2,4]triazolo[4,3-f]pteridinone, and 7-aminotetrazolo[1,5-f]pteridinone derivative as potent antitumor agents.

Wei Li, P. Gong, Yajing Liu, 2019, European journal of medicinal chemistry.

Palladium‐Catalyzed Three‐Component Tandem Reaction for One‐pot Highly Stereoselective Synthesis of (Z)‐α‐Hydroxymethyl Allylic Sulfones

P. Gong, Yanfang Zhao, Mingze Qin, 2018 .

Discovery of a novel 6,7-disubstituted-4-(2-fluorophenoxy)quinolines bearing 1,2,3-triazole-4-carboxamide moiety as potent c-Met kinase inhibitors.

Zhuang Guo, Ping Qian, Yunlei Hou, 2016, European journal of medicinal chemistry.

Regioselective construction of pyridazine and tetrahydrocinnoline derivatives via [4 + 2] cycloaddition–elimination with α-halogeno hydrazones and enaminones

Yucheng Gu, P. Gong, Yunlei Hou, 2020 .

Palladium-catalyzed three-component tandem cyclization of buta-2,3-dien-1-ol, aryl iodides, and imines: an efficient protocol for the synthesis of oxazolidine derivatives

P. Gong, Yanfang Zhao, Yajing Liu, 2017 .

A novel and unusual method for C N bond formation between benzene ring and various amines

Yanfang Zhao, Yunlei Hou, Sicong Xu, 2021, Tetrahedron Letters.

Design, synthesis and biological evaluation of novel 4-phenoxypyridine based 3-oxo-3,4-dihydroquinoxaline-2-carboxamide derivatives as potential c-Met kinase inhibitors.

Xianglong Zhu, Yajing Liu, Ye Chen, 2020, Bioorganic chemistry.

Novel 4-phenoxypyridine derivatives bearing imidazole-4-carboxamide and 1,2,4-triazole-3-carboxamide moieties: Design, synthesis and biological evaluation as potent antitumor agents.

Chunyan Li, Ye Chen, Ju Liu, 2022, Bioorganic chemistry.

Design, synthesis and biological evaluation of novel pteridinone derivatives possessing a hydrazone moiety as potent PLK1 inhibitors.

Yanfang Zhao, Yajing Liu, Liangyu Zhu, 2020, Bioorganic & medicinal chemistry letters.

Design, synthesis, and biological evaluation of 4-((6,7-dimethoxyquinoline-4-yl)oxy)aniline derivatives as FLT3 inhibitors for the treatment of acute myeloid leukemia.

P. Gong, Yajing Liu, Le-cun Xu, 2019, Bioorganic & medicinal chemistry letters.