Lei Yuan

发表

Discovery of a novel cathepsin inhibitor with dual autophagy-inducing and metastasis-inhibiting effects on breast cancer cells.

Enlong Ma, Yanchun Li, Jian Wang, 2019, Bioorganic chemistry.

Synthesis, Crystal and Calculated Structure, and Biological Activity of 2-((6-Bromo-2-methoxyquinolin-3-yl) (phenyl)methyl)-2,3,7,7a-tetrahydro-3a,6-epoxyisoindol-1(6H)-one

Li-juan Wang, Yu Chen, Chao Wang, 2012, Journal of Chemical Crystallography.

Identification of potential platelet-derived growth factor receptor α inhibitors by computational screening and binding simulations.

Enlong Ma, Yanchun Li, Jian Wang, 2019, Journal of molecular graphics & modelling.

A novel cathepsin L inhibitor prevents the progression of idiopathic pulmonary fibrosis.

Enlong Ma, Yanchun Li, Jian Wang, 2019, Bioorganic chemistry.

Synthesis and in vitro antitumor activity of asperphenamate derivatives as autophagy inducer.

Enlong Ma, Yanchun Li, Chao Wang, 2012, Bioorganic & medicinal chemistry letters.

Synthesis and anti-influenza virus activity evaluation of novel andrographolide derivatives

Lixia Chen, Lei Yuan, Chunfeng Jiang, 2022, Medicinal Chemistry Research.

Design and synthesis of dual cathepsin L and S inhibitors and antimetastatic activity evaluation in pancreatic cancer cells.

Enlong Ma, Yanchun Li, Ning Li, 2022, Bioorganic & medicinal chemistry letters.

Total synthesis and anticancer activity studies of the stereoisomers of asperphenamate and patriscabratine

Tiemin Sun, Lei Yuan, Jin-hui Wang, 2010 .

Design, synthesis and biological evaluation of novel asperphenamate derivatives.

Enlong Ma, Yang Liu, Wei Li, 2016, European journal of medicinal chemistry.

The semi-synthesis of novel andrographolide analogues and anti-influenza virus activity evaluation of their derivatives.

Lixia Chen, Jian Huang, Jinhui Wang, 2016, Bioorganic & medicinal chemistry letters.

Callistephus A, a novel sesquiterpene from the Callistephus chinensis flower

Gang Chen, Jia-qing Cao, Yu-qing Zhao, 2015 .

JNK-dependent Atg4 upregulation mediates asperphenamate derivative BBP-induced autophagy in MCF-7 cells.

Enlong Ma, Yanchun Li, Jian-chun Li, 2012, Toxicology and applied pharmacology.

Discovery of a novel and selective cathepsin L inhibitor with anti-metastatic ability in vitro and in vivo against breast cancer cells.

Enlong Ma, Yanchun Li, Yutong Liu, 2021, Bioorganic chemistry.

Isolation, structure elucidation, and synthesis of (±)-millpuline A with a suppressive effect in miR-144 expression

Gang Chen, Jian Wang, Ning Li, 2019, Organic Chemistry Frontiers.

Discovery of specific HDAC6 inhibitor with anti-metastatic effects in pancreatic cancer cells through virtual screening and biological evaluation.

Enlong Ma, Yanchun Li, Jian Wang, 2020, Bioorganic chemistry.

Discovery of novel cathepsin inhibitors with potent anti-metastatic effects in breast cancer cells.

Enlong Ma, Jian Wang, Yang Liu, 2018, Bioorganic chemistry.

ASPER-29 suppresses the metastasis of pancreatic cancer cells by dual inhibition of cathepsin-L and cathepsin-S.

Enlong Ma, Yanchun Li, Tianyi Dong, 2022, Chemico-biological interactions.

Synthesis, crystal, computational study and in vitro anti-tuberculosis activity of N -(furan-2-yl-methyl)- N -(phenyl(quinolin-3-yl)methyl) acetamide derivatives

W. Xu, Li-juan Wang, Yu Chen, 2011 .