M. Kubryk

发表

Synthesis of Sitagliptin

Feng Xu, Edward J. J. Grabowski, Shane W. Krska, 2009 .

Highly efficient asymmetric synthesis of sitagliptin.

Feng Xu, Andrew Clausen, Shane W. Krska, 2009, Journal of the American Chemical Society.

Oxopyrido[2,3-d]pyrimidines as Covalent L858R/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors.

E. Lobenhofer, Kristin L. Andrews, B. Herberich, 2015, ACS medicinal chemistry letters.

An Improved Process for the Preparation of a Covalent Kinase Inhibitor through a C–N Bond-Forming SNAr Reaction

A. T. Parsons, O. Thiel, Matthew S. Potter-Racine, 2018, Organic Process Research & Development.

Detection and elimination of product inhibition from the asymmetric catalytic hydrogenation of enamines.

J. Armstrong, P. Dormer, K. Hansen, 2005, Organic letters.

First Generation Process for the Preparation of the DPP-IV Inhibitor Sitagliptin

Edward J. J. Grabowski, Spencer D. Dreher, J. Armstrong, 2005 .

Synthesis of [1,2,4]Triazolo[4,3-α]piperazines via Highly Reactive Chloromethyloxadiazoles

J. Armstrong, Jinchu Liu, J. Balsells, 2005 .

Remote desymmetrization at near-nanometer group separation catalyzed by a miniaturized enzyme mimic.

Scott J. Miller, R. Reamer, David Pollard, 2006, Journal of the American Chemical Society.

Scalable, efficient process for the synthesis of (R)-3,5-bistrifluoromethylphenyl ethanol via catalytic asymmetric transfer hydrogenation and isolation as a DABCO inclusion complex

Paul N. Devine, D. Mathre, E. Grabowski, 2003 .

Application of the asymmetric hydrogenation of enamines to the preparation of a beta-amino acid pharmacophore

K. Hansen, M. Kubryk, 2006 .

Oxopyrido[2,3-d]pyrimidines as Covalent L858R/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors.

E. Lobenhofer, B. Herberich, A. Tasker, 2015, ACS Medicinal Chemistry Letters.