A. Colapietro

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Dual CXCR4 and E-Selectin Inhibitor, GMI-1359, Shows Anti-Bone Metastatic Effects and Synergizes with Docetaxel in Prostate Cancer Cell Intraosseous Growth

A. Vetuschi, L. Ventura, J. Magnani, 2019, Cells.

The Brain Penetrating and Dual TORC1/TORC2 Inhibitor, RES529, Elicits Anti-Glioma Activity and Enhances the Therapeutic Effects of Anti-Angiogenetic Compounds in Preclinical Murine Models

R. Sferra, D. Sherris, F. Vitale, 2019, Cancers.

Impregnation of Curcumin into a Biodegradable (Poly-lactic-co-glycolic acid, PLGA) Support, to Transfer Its Well Known In Vitro Effect to an In Vivo Prostate Cancer Model

M. Carmona, I. Gracia, C. Festuccia, 2019, Nutrients.

Expression of Peroxisome Proliferator-Activated Receptor Alpha (PPARα) in Non-Somatotroph Pituitary Tumours and the Effects of PPARα Agonists on MMQ Cells

V. Esposito, A. Angelucci, M. Jaffrain-Rea, 2018, Hormone and Metabolic Research.

Neurovascular alterations of muscularis propria in the human anterior vaginal wall in pelvic organ prolapse

A. Vetuschi, R. Sferra, E. Gaudio, 2019, Journal of anatomy.

Abundances of autophagy-related protein LC3B in granulosa cells, cumulus cells, and oocytes during atresia of pig antral follicles.

C. Festuccia, A. Contri, A. Gloria, 2019, Animal reproduction science.

The Small Molecule Ephrin Receptor Inhibitor, GLPG1790, Reduces Renewal Capabilities of Cancer Stem Cells, Showing Anti-Tumour Efficacy on Preclinical Glioblastoma Models

R. Sferra, E. M. van der Aar, F. Vitale, 2019, Cancers.

Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgen-independent prostate cancer cells to DNA damage

A. Vetuschi, R. Sferra, E. Gaudio, 2015, Oncotarget.

Multiple Antitumor Molecular Mechanisms Are Activated by a Fully Synthetic and Stabilized Pharmaceutical Product Delivering the Active Compound Sulforaphane (SFX-01) in Preclinical Model of Human Glioblastoma

G. Gravina, L. Biordi, C. Festuccia, 2021, Pharmaceuticals.

Dual PI3 K/mTOR inhibition reduces prostate cancer bone engraftment altering tumor-induced bone remodeling

A. Angelucci, C. Liang, G. Gravina, 2018, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.

The Botanical Drug PBI-05204, a Supercritical CO2 Extract of Nerium Oleander, Is Synergistic With Radiotherapy in Models of Human Glioblastoma

R. Newman, Peiying Yang, F. Vitale, 2022, Frontiers in Pharmacology.

The Botanical Drug PBI-05204, a Supercritical CO2 Extract of Nerium Oleander, Inhibits Growth of Human Glioblastoma, Reduces Akt/mTOR Activities, and Modulates GSC Cell-Renewal Properties

R. Newman, Peiying Yang, D. Wei, 2020, Frontiers in Pharmacology.

Enhancement of radiosensitivity by the novel anticancer quinolone derivative vosaroxin in preclinical glioblastoma models

A. Vetuschi, E. Di Cesare, L. Ventura, 2016, Oncotarget.

Crocetin and Crocin from Saffron in Cancer Chemotherapy and Chemoprevention.

C. Festuccia, A. D’Alessandro, A. Mancini, 2019, Anti-cancer agents in medicinal chemistry.

Crocetin Extracted from Saffron Shows Antitumor Effects in Models of Human Glioblastoma

G. Alonso, A. Angelucci, S. Llorens, 2020, International journal of molecular sciences.

The Importance of Tumor Stem Cells in Glioblastoma Resistance to Therapy

F. Santilli, A. Angelucci, C. Festuccia, 2021, International journal of molecular sciences.

Anticancer effects of ABTL0812, a clinical stage drug inducer of autophagy-mediated cancer cell death, in glioblastoma models

M. Yeste-Velasco, G. Gravina, C. Festuccia, 2022, Frontiers in Oncology.

ATX-101, a Peptide Targeting PCNA, Has Antitumor Efficacy Alone or in Combination with Radiotherapy in Murine Models of Human Glioblastoma

M. Otterlei, G. Gravina, L. Biordi, 2022, Cancers.

Antitumorigenic Effects of Inhibiting Ephrin Receptor Kinase Signaling by GLPG1790 against Colorectal Cancer Cell Lines In Vitro and In Vivo

R. Maggio, V. Tombolini, E. M. van der Aar, 2020, Journal of oncology.

Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment.

F. Musumeci, C. Zamperini, A. L. Fallacara, 2018, Bioorganic & medicinal chemistry letters.

The novel CXCR4 antagonist, PRX177561, reduces tumor cell proliferation and accelerates cancer stem cell differentiation in glioblastoma preclinical models

S. Burbidge, A. Vetuschi, P. Richardson, 2017, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.

UniPR1331, a small molecule targeting Eph/ephrin interaction, prolongs survival in glioblastoma and potentiates the effect of antiangiogenic therapy in mice

R. Sferra, M. Rusnati, P. Chiodelli, 2018, Oncotarget.

Correction to: The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma

A. Vetuschi, V. Tombolini, F. Vitale, 2018, Journal of Hematology & Oncology.

The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma

A. Vetuschi, V. Tombolini, F. Vitale, 2018, Journal of Hematology & Oncology.

Increased expression and activity of p75NTR are crucial events in azacitidine-induced cell death in prostate cancer.

C. Ficorella, P. Sanità, G. Gravina, 2016, Oncology reports.

The brain-penetrating CXCR4 antagonist, PRX177561, increases the antitumor effects of bevacizumab and sunitinib in preclinical models of human glioblastoma

S. Burbidge, R. Sferra, P. Richardson, 2017, Journal of Hematology & Oncology.

Episode-like pulse testosterone supplementation induces tumor senescence and growth arrest down-modulating androgen receptor through modulation of p-ERK1/2, pARser81 and CDK1 signaling: biological implications for men treated with testosterone replacement therapy

A. Lenzi, A. Vetuschi, R. Sferra, 2017, Oncotarget.

Dual PI3K/mTOR inhibitor, XL765 (SAR245409), shows superior effects to sole PI3K [XL147 (SAR245408)] or mTOR [rapamycin] inhibition in prostate cancer cell models

E. Ricevuto, F. Vitale, G. Gravina, 2015, Tumor Biology.

Immunolocalization of Advanced Glycation End Products, Mitogen Activated Protein Kinases, and Transforming Growth Factor-β/Smads in Pelvic Organ Prolapse

A. Vetuschi, R. Sferra, E. Gaudio, 2018, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

c-Myc Sustains Transformed Phenotype and Promotes Radioresistance of Embryonal Rhabdomyosarcoma Cell Lines

P. Sanità, E. Di Cesare, V. Tombolini, 2016, Radiation Research.

Pharmacological treatment with inhibitors of nuclear export enhances the antitumor activity of docetaxel in human prostate cancer

R. Sferra, V. Flati, Y. Landesman, 2017, Oncotarget.

The novel CXCR4 antagonist, PRX177561, reduces tumor cell proliferation and accelerates cancer stem cell differentiation in glioblastoma preclinical models

S. Burbidge, A. Vetuschi, P. Richardson, 2017, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.