Michael P. Ludwig

ΔNp63α Suppresses TGFB2 Expression and RHOA Activity to Drive Cell Proliferation in Squamous Cell Carcinomas.

J. Espinosa, M. Galbraith, Z. Andrysik, 2018, Cell reports.

Interferon receptor gene dosage determines diverse hallmarks of Down syndrome

J. Espinosa, M. Galbraith, Z. Andrysik, 2022, bioRxiv.

Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors

Rani K. Powers, J. Costello, A. Lleó, 2019, Nature Communications.

Trisomy 21 drives production of neurotoxic tryptophan catabolites via the interferon-inducible kynurenine pathway

Rani K. Powers, J. Costello, A. D’Alessandro, 2018, bioRxiv.

JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome.

J. Espinosa, Z. Andrysik, Keith P. Smith, 2020, Cell reports.

Autophagy Inhibition Mediates Apoptosis Sensitization in Cancer Therapy by Relieving FOXO3a Turnover.

A. Thorburn, J. Espinosa, Z. Andrysik, 2018, Developmental cell.

JAK1 inhibition blocks lethal sterile immune responses: implications for COVID-19 therapy

J. Espinosa, Z. Andrysik, Keith P. Smith, 2020, bioRxiv.