Hao Zhang

发表

Functional Blockade of the Voltage-gated Potassium Channel Kv1.3 Mediates Reversion of T Effector to Central Memory Lymphocytes through SMAD3/p21cip1 Signaling*

J. Margolick, P. Calabresi, J. Rosenzweig, 2011, The Journal of Biological Chemistry.

Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance

J. Margolick, E. Petricoin, L. Liotta, 2007, Proceedings of the National Academy of Sciences.

ATM-dependent phosphorylation of the checkpoint clamp regulates repair pathways and maintains genomic stability

J. Margolick, Mihoko Kai, M. Yuan, 2012, Cell cycle.

Preservation of FoxP3 (cid:1) Regulatory T Cells in the Peripheral Blood of Human Immunodeﬁciency Virus Type 1-Infected Elite Suppressors Correlates with Low CD4 (cid:1) T-Cell Activation (cid:1)

R. Siliciano, J. Blankson, Hung‐Chih Yang, 2008 .

Single-cell transcriptional landscapes reveal HIV-1–driven aberrant host gene transcription as a potential therapeutic target

F. Bushman, M. Pertea, D. Douek, 2020, Science Translational Medicine.

A Protective Role for Human IL-10–Expressing CD4+ T Cells in Colitis

J. Margolick, C. Brayton, J. Bream, 2012, The Journal of Immunology.

Genome-wide CRISPR screens identify combinations of candidate latency reversing agents for targeting the latent HIV-1 reservoir

R. Siliciano, J. Siliciano, Wei Li, 2022, Science Translational Medicine.

A clinically relevant population of leukemic CD34(+)CD38(-) cells in acute myeloid leukemia.

M. Borowitz, L. Morsberger, Richard J. Jones, 2012, Blood.

Multiple genetic programs contribute to CD4 T cell memory differentiation and longevity by maintaining T cell quiescence

R. Siliciano, John-William Sidhom, C. Jie, 2020, Cellular immunology.

A novel quantitative approach for measuring the reservoir of latent HIV-1 proviruses

R. Siliciano, F. Bushman, J. Margolick, 2019, Nature.

Novel Pathway for Induction of Latent Virus from Resting CD4+ T Cells in the Simian Immunodeficiency Virus/Macaque Model of Human Immunodeficiency Virus Type 1 Latency

Yan Zhou, Robert F. Siliciano, R. Siliciano, 2006, Journal of Virology.

Transcriptional Reprogramming during Effector‐to‐Memory Transition Renders CD4+ T Cells Permissive for Latent HIV‐1 Infection

R. Siliciano, J. Margolick, J. Siliciano, 2017, Immunity.

In vitro modeling of the HIV‐macrophage reservoir

Amanda M. Brown, C. Pardo, S. Gartner, 2006, Journal of leukocyte biology.

Influence of Host Gene Transcription Level and Orientation on HIV-1 Latency in a Primary-Cell Model

R. Siliciano, J. Margolick, H. Bravo, 2011, Journal of Virology.

Preservation of FoxP3+ Regulatory T Cells in the Peripheral Blood of Human Immunodeficiency Virus Type 1-Infected Elite Suppressors Correlates with Low CD4+ T-Cell Activation

R. Siliciano, J. Blankson, Hung‐Chih Yang, 2008, Journal of Virology.

HIV-1 RNA A Novel PCR Assay for Quantification of

J. Margolick, G. Laird, Hao Zhang, 2014 .

A Novel PCR Assay for Quantification of HIV-1 RNA

R. Siliciano, J. Margolick, G. Laird, 2013, Journal of Virology.

A Novel Assay Allows Genotyping of the Latent Reservoir for Human Immunodeficiency Virus Type 1 in the Resting CD4+ T Cells of Viremic Patients

Thomas C. Quinn, Yan Zhou, Tara L. Kieffer, 2005, Journal of Virology.

Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation.

R. Siliciano, J. Margolick, J. Blankson, 2012, Immunity.

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

R. Siliciano, S. Salzberg, J. Margolick, 2015, Nature.

Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4+ T Cell Model without Inducing Global T Cell Activation

R. Siliciano, J. Margolick, T. Quinn, 2011, Journal of Virology.

Antigen-driven clonal selection shapes the persistence of HIV-1 infected CD4+ T cells in vivo

R. Siliciano, F. Bushman, J. Margolick, 2020, bioRxiv.

Different human resting memory CD4+ T cell subsets show similar low inducibility of latent HIV-1 proviruses

R. Siliciano, J. Siliciano, S. Deeks, 2020, Science Translational Medicine.

Clonally expanded HIV-1 proviruses with 5′-leader defects can give rise to nonsuppressible residual viremia

R. Siliciano, J. Siliciano, C. Tremblay, 2023, The Journal of clinical investigation.

The Latent Human Immunodeficiency Virus (HIV) Reservoir Resides Primarily in CD32−CD4+ T Cells in Perinatally HIV-Infected Adolescents With Long-Term Virologic Suppression

Lilly Siems, D. Persaud, Dolly Singh, 2018, The Journal of infectious diseases.

The role of CD32 during HIV-1 infection

R. Siliciano, J. Margolick, L. Montaner, 2018, Nature.

A novel quantitative approach for measuring the reservoir of latent HIV-1 proviruses

R. Siliciano, F. Bushman, J. Margolick, 2019, Nature.

Majority of the latent reservoir resides in CD32a negative CD4+ T cells

R. Siliciano, J. Margolick, L. Montaner, 2017 .

Stability of the latent reservoir for HIV-1 in patients receiving valproic acid.

Richard D Moore, R. Siliciano, J. Margolick, 2007, The Journal of infectious diseases.

Keratin intracellular concentration revisited: Implications for keratin function in surface epithelia

J. Margolick, P. Coulombe, Xia Feng, 2012, The Journal of investigative dermatology.

Diverse fates of uracilated HIV-1 DNA during infection of myeloid lineage cells

R. Siliciano, J. Hesselberth, Nina N. Hosmane, 2016, eLife.

Research advances in cGAS–stimulator of interferon genes pathway and central nervous system diseases: Focus on new therapeutic approaches

Xuemei Fan, B. Tang, Hao Zhang, 2022, Frontiers in Molecular Neuroscience.

Late-emerging strains of HIV induce T-cell homeostasis failure by promoting bystander cell death and immune exhaustion in naïve CD4 and all CD8 T-cells.

J. Margolick, C. Kibirige, Tricia L. Nilles, 2014, Medical hypotheses.

Unique transcriptional profile of liver-resident memory CD8+ T cells induced by immunization with malaria sporozoites

A. Scott, F. Zavala, I. Cockburn, 2013, Genes and Immunity.

Unique characteristics of histone deacetylase inhibitors in reactivation of latent HIV-1 in Bcl-2-transduced primary resting CD4+ T cells.

R. Siliciano, J. Margolick, Hung‐Chih Yang, 2014, The Journal of antimicrobial chemotherapy.

HIV-1 DNA is detected in bone marrow populations containing CD4+ T cells but is not found in purified CD34+ hematopoietic progenitor cells in most patients on antiretroviral therapy.

R. Siliciano, J. Margolick, J. Gallant, 2012, The Journal of infectious diseases.

Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance (Proceedings of the National Academy of Sciences of the United States of America (2007) 104, 41 (16158-16163))

J. Margolick, E. Petricoin, L. Liotta, 2007 .

Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation

Jun O. Liu, R. Siliciano, J. Margolick, 2011, The Journal of antimicrobial chemotherapy.

TCR-mimic bispecific antibodies to target the HIV-1 reservoir

R. Siliciano, K. Kinzler, B. Vogelstein, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation.

R. Siliciano, J. Margolick, J. Blankson, 2012, Immunity.

Unique characteristics of histone deacetylase inhibitors in reactivation of latent HIV-1 in Bcl-2-transduced primary resting CD4+ T cells.

R. Siliciano, J. Margolick, Hung‐Chih Yang, 2014, The Journal of antimicrobial chemotherapy.

Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4+ T Cell Model without Inducing Global T Cell Activation

R. Siliciano, J. Margolick, T. Quinn, 2011, Journal of Virology.

CD4+ T cells with latent HIV-1 have reduced proliferative responses to T cell receptor stimulation

R. Siliciano, J. Lai, F. Simonetti, 2024, The Journal of experimental medicine.

Cognate Antigen Engagement Induces HIV-1 Expression In CD4+ T Cells From People On Long-Term ART

R. Siliciano, L. Montaner, K. Mounzer, 2024, bioRxiv.