Shin Kumadaki

Inhibition of Ubiquitin Ligase F-box and WD Repeat Domain-containing 7α (Fbw7α) Causes Hepatosteatosis through Krüppel-like Factor 5 (KLF5)/Peroxisome Proliferator-activated Receptor γ2 (PPARγ2) Pathway but Not SREBP-1c Protein in Mice*

Satoru Takahashi, H. Sone, H. Shimano, 2011, The Journal of Biological Chemistry.

Cholesterol accumulation and diabetes in pancreatic beta-cell-specific SREBP-2 transgenic mice: a new model for lipotoxicity.

H. Shimano, N. Yahagi, N. Yamada, 2008, Journal of lipid research.

Granuphilin is activated by SREBP-1c and involved in impaired insulin secretion in diabetic mice.

H. Gomi, Satoru Takahashi, H. Sone, 2006, Cell metabolism.

Mouse Elovl-6 promoter is an SREBP target.

H. Shimano, N. Yahagi, N. Yamada, 2008, Biochemical and biophysical research communications.

Intestine-Targeted DGAT1 Inhibition Improves Obesity and Insulin Resistance without Skin Aberrations in Mice

M. Ozawa, Yoshihiro Ogawa, Chika Higashi, 2014, PloS one.

Palmitate Impairs and Eicosapentaenoate Restores Insulin Secretion Through Regulation of SREBP-1c in Pancreatic Islets

H. Sone, H. Shimano, N. Yahagi, 2008, Diabetes.

Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance

Hitoshi Shimano, Mayumi Ishikawa, Takashi Matsuzaka, 2007, Nature Medicine.

The liver-enriched transcription factor CREBH is nutritionally regulated and activated by fatty acids and PPARalpha.

H. Shimano, N. Yamada, T. Matsuzaka, 2010, Biochemical and biophysical research communications.