Simon-Pierre Gravel

发表

Involvement of the IκB Kinase (IKK)-Related Kinases Tank-Binding Kinase 1/IKKi and Cullin-Based Ubiquitin Ligases in IFN Regulatory Factor-3 Degradation1

J. Hiscott, S. Meloche, G. Rodier, 2006, The Journal of Immunology.

Low expression of PGC-1β and other mitochondrial biogenesis modulators in melanoma is associated with growth arrest and the induction of an immunosuppressive gene expression program dependent on MEK and IRF-1.

É. Audet-Walsh, Simon-Pierre Gravel, Karl M. Laurin, 2022, Cancer letters.

Involvement of the IκB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation

J. Hiscott, S. Meloche, G. Rodier, 2006, The Journal of Immunology.

Current knowledge on the tissue distribution of mRNA nanocarriers for therapeutic protein expression.

D. Brambilla, Samuel Babity, Simon-Pierre Gravel, 2022, Biomaterials science.

Stable Isotope Tracer Analysis in Isolated Mitochondria from Mammalian Systems

D. Avizonis, J. St-Pierre, Sylvia Andrzejewski, 2014, Metabolites.

The Proinflammatory Actions of Angiotensin II Are Dependent on p65 Phosphorylation by the IκB Kinase Complex*

S. Gravel, M. Servant, P. Moreau, 2006, Journal of Biological Chemistry.

mTOR coordinates protein synthesis, mitochondrial activity and proliferation

O. Larsson, M. Pollak, I. Topisirovic, 2015, Cell cycle.

mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation.

N. Sonenberg, T. Alain, A. Pause, 2013, Cell metabolism.

Metformin directly acts on mitochondria to alter cellular bioenergetics

M. Pollak, J. St-Pierre, Sylvia Andrzejewski, 2014, Cancer & metabolism.

Alternative polyadenylation confers Pten mRNAs stability and resistance to microRNAs

T. Duchaine, C. Lussier, Vinay K. Mayya, 2018, Nucleic acids research.

PGC-1α supports glutamine metabolism in breast cancer

B. Faubert, Russell G. Jones, U. Akavia, 2013, Cancer & metabolism.

AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species.

E. Ma, B. Faubert, Russell G. Jones, 2017, Cell reports.

Translational and HIF1α-dependent metabolic reprograming underpin oncometabolome plasticity and synergy between oncogenic kinase inhibitors and biguanides

C. Greenwood, J. Ursini-Siegel, M. Ohh, 2017, bioRxiv.

Serine deprivation enhances antineoplastic activity of biguanides.

M. Pollak, I. Topisirovic, E. Birman, 2014, Cancer research.

Therapeutics , Targets , and Chemical Biology Serine Deprivation Enhances Antineoplastic Activity of Biguanides

M. Pollak, I. Topisirovic, E. Birman, 2014 .

Deciphering the Dichotomous Effects of PGC-1α on Tumorigenesis and Metastasis

Simon-Pierre Gravel, 2018, Front. Oncol..

Metabolomics Analyses of Cancer Cells in Controlled Microenvironments.

D. Avizonis, S. Gravel, J. St-Pierre, 2016, Methods in molecular biology.

ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer

Maxime Caron, Guillaume Bourque, Morag Park, 2016, Nature Communications.

nanoCAGE reveals 5′ UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs

J. Pelletier, O. Larsson, Marie Cargnello, 2016, Genome research.

Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides.

C. Greenwood, E. Ma, Russell G. Jones, 2018, Cell metabolism.

The complete targeted profile of the organic acid intermediates of the citric acid cycle using a single stable isotope dilution analysis, sodium borodeuteride reduction and selected ion monitoring GC/MS

D. Avizonis, O. Mamer, J. St-Pierre, 2013, Metabolomics.

Immunometabolic modulation of retinal inflammation by CD36 ligand

P. Hardy, S. Omri, S. Chemtob, 2019, Scientific Reports.

PRL2 links magnesium flux and sex-dependent circadian metabolic rhythms.

S. Hardy, M. Tremblay, S. Kiessling, 2017, JCI insight.

The PGC-1α/ERRα Axis Represses One-Carbon Metabolism and Promotes Sensitivity to Anti-folate Therapy in Breast Cancer.

G. Bourque, V. Giguère, M. Caron, 2016, Cell reports.

RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in Melanoma.

L. Gaboury, G. Lavoie, Antoine Méant, 2018, Cancer research.

PGC-1α supports glutamine metabolism in breast cancer

B. Faubert, Russell G. Jones, U. Akavia, 2013, Cancer & Metabolism.

Roles of an IkappaB kinase-related pathway in human cytomegalovirus-infected vascular smooth muscle cells: a molecular link in pathogen-induced proatherosclerotic conditions.

M. Servant, Simon-Pierre Gravel, 2005, The Journal of biological chemistry.

Interplay between ShcA Signaling and PGC-1α Triggers Targetable Metabolic Vulnerabilities in Breast Cancer.

T. Pawson, J. Ursini-Siegel, M. Pollak, 2018, Cancer research.

Phosphorylation of IRF-3 on Ser 339 Generates a Hyperactive Form of IRF-3 through Regulation of Dimerization and CBP Association

P. Thibault, S. Meloche, N. Grandvaux, 2008, Journal of Virology.

A salicylic acid derivative extends the lifespan of Caenorhabditis elegans by activating autophagy and the mitochondrial unfolded protein response

H. Aguilaniu, J. St-Pierre, L. Breton, 2018, Aging cell.

LKB1 deficiency in T cells promotes the development of gastrointestinal polyposis

E. Ma, S. Gravel, N. Beauchemin, 2018, Science.

mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation.

N. Sonenberg, T. Alain, A. Pause, 2013, Cell metabolism.

Translational and HIF1α-dependent metabolic reprograming underpin oncometabolome plasticity and synergy between oncogenic kinase inhibitors and biguanides

C. Greenwood, M. Ohh, O. Larsson, 2017, bioRxiv.

Metabolomics Analyses of Cancer Cells in Controlled Microenvironments.

D. Avizonis, J. St-Pierre, Simon-Pierre Gravel, 2016, Methods in molecular biology.

PGC-1s shape epidermal physiology by modulating keratinocyte proliferation and terminal differentiation.

D. D'Amours, J. St-Pierre, L. Breton, 2023, iScience.

Paraspeckle-independent co-transcriptional regulation of nuclear microRNA biogenesis by SFPQ.

A. Gingras, T. Duchaine, Simon-Pierre Gravel, 2024, Cell reports.