Ryotaro Saiki

发表

Role of polyamines at the G1/S boundary and G2/M phase of the cell cycle.

K. Kashiwagi, K. Higashi, K. Igarashi, 2013, The international journal of biochemistry & cell biology.

Polyphenol Extract from Phellinus igniarius Protects against Acrolein Toxicity In Vitro and Provides Protection in a Mouse Stroke Model

K. Higashi, K. Igarashi, T. Toida, 2015, PloS one.

Relationship between metabolic disorders and relative risk values of brain infarction estimated by protein-conjugated acrolein, IL-6 and CRP together with age.

K. Kashiwagi, E. Kobayashi, H. Takizawa, 2011, Clinica chimica acta; international journal of clinical chemistry.

Acrolein stimulates the synthesis of IL‐6 and C‐reactive protein (CRP) in thrombosis model mice and cultured cells

K. Kashiwagi, Kaoru Kobayashi, K. Chiba, 2013, Journal of neurochemistry.

Acrolein-conjugated low-density lipoprotein induces macrophage foam cell formation.

Kenta Watanabe, K. Igarashi, I. Ishii, 2013, Atherosclerosis.

Design, synthesis, and evaluation of polyamine-memantine hybrids as NMDA channel blockers.

Takuya Kumamoto, K. Igarashi, T. Ishikawa, 2017, Bioorganic & medicinal chemistry.

Intense Correlation Between Brain Infarction and Protein-Conjugated Acrolein

S. Okuyama, K. Kashiwagi, K. Igarashi, 2009, Stroke.

Activation of MMP-9 activity by acrolein in saliva from patients with primary Sjögren's syndrome and its mechanism.

S. Ito, K. Kashiwagi, Takehiro Suzuki, 2017, The international journal of biochemistry & cell biology.

Toxic acrolein production due to Ca(2+) influx by the NMDA receptor during stroke.

K. Kashiwagi, K. Igarashi, T. Toida, 2016, Atherosclerosis.

AMD1 is essential for ESC self-renewal and is translationally down-regulated on differentiation to neural precursor cells.

L. Vardy, Dawei Zhang, Henry Yang, 2012, Genes & development.

AMD 1 is essential for ESC self-renewal and is translationally down-regulated on differentiation to neural precursor cells

L. Vardy, Dawei Zhang, Henry Yang, 2012 .

Aggravation of brain infarction through an increase in acrolein production and a decrease in glutathione with aging.

K. Kashiwagi, Kenta Watanabe, K. Igarashi, 2016, Biochemical and biophysical research communications.

Inactivation of GAPDH as one mechanism of acrolein toxicity.

K. Kashiwagi, Takehiro Suzuki, N. Dohmae, 2013, Biochemical and biophysical research communications.

Increased protein-conjugated acrolein and amyloid-β40/42 ratio in plasma of patients with mild cognitive impairment and Alzheimer's disease.

H. Arai, K. Kashiwagi, M. Waragai, 2012, Journal of Alzheimer's disease : JAD.

Brain infarction correlates more closely with acrolein than with reactive oxygen species.

S. Kojima, K. Kashiwagi, A. Pegg, 2011, Biochemical and biophysical research communications.

Structural Changes of Regulatory Domain Heterodimer of N-Methyl-d-aspartate Receptor Subunits GluN1 and GluN2B through the Binding of Spermine and Ifenprodil

K. Williams, T. Masuko, K. Kashiwagi, 2012, Journal of Pharmacology and Experimental Therapeutics.

Inverse correlation between stroke and urinary 3-hydroxypropyl mercapturic acid, an acrolein-glutathione metabolite.

K. Kashiwagi, Takao Nakamura, K. Higashi, 2012, Clinica chimica acta; international journal of clinical chemistry.

Time dependent transition of the levels of protein-conjugated acrolein (PC-Acro), IL-6 and CRP in plasma during stroke

K. Kashiwagi, Y. Murayama, K. Igarashi, 2017, eNeurologicalSci.

Increase in acrolein-conjugated immunoglobulins in saliva from patients with primary Sjögren's syndrome.

S. Ito, K. Kashiwagi, Takehiro Suzuki, 2015, Clinica chimica acta; international journal of clinical chemistry.

Distinguishing mild cognitive impairment from Alzheimer's disease with acrolein metabolites and creatinine in urine.

K. Kashiwagi, M. Waragai, K. Higashi, 2015, Clinica chimica acta; international journal of clinical chemistry.

Distinction between mild cognitive impairment and Alzheimer's disease by CSF amyloid β40 and β42, and protein-conjugated acrolein.

K. Kashiwagi, M. Waragai, K. Igarashi, 2014, Clinica chimica acta; international journal of clinical chemistry.

Identification of Functional Amino Acid Residues Involved in Polyamine and Agmatine Transport by Human Organic Cation Transporter 2

K. Kashiwagi, K. Higashi, K. Igarashi, 2014, PloS one.

Spermidine and Ca(2+), but not Na(+), can permeate NMDA receptors consisting of GluN1 and GluN2A or GluN2B in the presence of Mg(2+).

K. Williams, K. Kashiwagi, K. Higashi, 2015, Biochemical and biophysical research communications.