K. Khan

发表

Activation of Key Profibrotic Mechanisms in Transgenic Fibroblasts Expressing Kinase-deficient Type II Transforming Growth Factor-β Receptor (TβRIIΔk)*

D. Abraham, C. Denton, E. Renzoni, 2005, Journal of Biological Chemistry.

Expression of Somatostatin and Dopamine 2 Receptors in Neuroendocrine Tumours and the Potential Role for New Biotherapies

R. Srirajaskanthan, M. Caplin, L. Marelli, 2009, Neuroendocrinology.

Critical Limb Ischaemia in Adult Human Skeletal Muscle Increases Satellite Cell Proliferation but Not Differentiation

D. Baker, D. Abraham, X. Shiwen, 2015 .

Focal adhesion kinase and reactive oxygen species contribute to the persistent fibrotic phenotype of lesional scleroderma fibroblasts.

M. Baron, D. Abraham, C. Denton, 2012, Rheumatology.

Cross-talk between MCP-3 and TGFbeta promotes fibroblast collagen biosynthesis.

D. Abraham, C. Denton, V. Ong, 2009, Experimental cell research.

Sustained improvement of diffuse systemic sclerosis following human cytomegalovirus infection offers insight into pathogenesis and therapy.

C. Denton, P. Moinzadeh, V. Ong, 2012, Rheumatology.

Mucosal Addressin Cell Adhesion Molecule (MAdCAM-1) Expression Is Upregulated in the Cirrhotic Liver and Immunolocalises to the Peribiliary Plexus and Lymphoid Aggregates

R. Standish, K. Hillan, T. Schiano, 2013, Digestive Diseases and Sciences.

Endothelial injury in a transforming growth factor β-dependent mouse model of scleroderma induces pulmonary arterial hypertension.

D. Abraham, C. Denton, A. Holmes, 2013, Arthritis and rheumatism.

Loss of protein kinase Cϵ results in impaired cutaneous wound closure and myofibroblast function

Yunliang Chen, D. Abraham, C. Denton, 2008, Journal of Cell Science.

Levels of target activation predict antifibrotic responses to tyrosine kinase inhibitors

R. Gay, S. Gay, D. Abraham, 2013, Annals of the rheumatic diseases.

Failed Degradation of JunB Contributes to Overproduction of Type I Collagen and Development of Dermal Fibrosis in Patients With Systemic Sclerosis

D. Abraham, C. Denton, A. Holmes, 2014, Arthritis & rheumatology.

Systemic vasculopathy with altered vasoreactivity in a transgenic mouse model of scleroderma

C. Denton, X. Shi-wen, A. Dooley, 2010, Arthritis research & therapy.

Heparan sulfate-dependent ERK activation contributes to the overexpression of fibrotic proteins and enhanced contraction by scleroderma fibroblasts.

Yunliang Chen, A. Pitsillides, D. Abraham, 2008, Arthritis and rheumatism.

Endocytosis of Anti-CCK-B/Gastrin Receptor Antibody and Effect on Hepatoma Cell Lines

S. Watson, K. Savage, M. Caplin, 2002, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Targeting of cholecystokinin B/gastrin receptor in colonic, pancreatic and hepatocellular carcinoma cell lines.

S. Watson, P. Clarke, K. Savage, 2006, International journal of oncology.

Transforming growth factor-β-induced CUX1 isoforms are associated with fibrosis in systemic sclerosis lung fibroblasts

C. Morimoto, D. Abraham, C. Denton, 2016, Biochemistry and biophysics reports.

Loss of protein kinase C&egr; results in impaired cutaneous wound closure and myofibroblast function

Yunliang Chen, D. Abraham, C. Denton, 2014, Journal of Cell Science.

Multiplex cytokine analysis of dermal interstitial blister fluid defines local disease mechanisms in systemic sclerosis

D. Abraham, C. Denton, G. Martin, 2015, Arthritis Research & Therapy.

Analysis of Anti-RNA Polymerase III Antibody-positive Systemic Sclerosis and Altered GPATCH2L and CTNND2 Expression in Scleroderma Renal Crisis

M. Mayes, Javier Martín, V. Acquaah, 2020, The Journal of Rheumatology.

Pivotal role of connective tissue growth factor in lung fibrosis: MAPK-dependent transcriptional activation of type I collagen.

D. Abraham, C. Denton, A. Holmes, 2009, Arthritis and rheumatism.

An essential role for resident fibroblasts in experimental lung fibrosis is defined by lineage-specific deletion of high-affinity type II transforming growth factor β receptor.

A. Wells, D. Abraham, C. Denton, 2011, American journal of respiratory and critical care medicine.

Inducible lineage-specific deletion of TbetaRII in fibroblasts defines a pivotal regulatory role during adult skin wound healing.

Yunliang Chen, D. Abraham, C. Denton, 2009, The Journal of investigative dermatology.

CCK2 gastrin receptor as a potential target for therapy in leukaemia cell lines.

K. Ganeshaguru, R. Wickremasinghe, M. Stubbs, 2005, Oncology reports.

Fibroblast-specific perturbation of transforming growth factor beta signaling provides insight into potential pathogenic mechanisms of scleroderma-associated lung fibrosis: exaggerated response to alveolar epithelial injury in a novel mouse model.

R. D. du Bois, A. Wells, D. Abraham, 2008, Arthritis and rheumatism.

Clinical and pathological significance of interleukin 6 overexpression in systemic sclerosis

D. Abraham, C. Denton, S. Nihtyanova, 2012, Annals of the rheumatic diseases.

Expression of the HER-1-4 family of receptor tyrosine kinases in neuroendocrine tumours.

R. Srirajaskanthan, M. Caplin, T. Shah, 2010, Oncology reports.

Lymphatic and blood vessels in scleroderma skin, a morphometric analysis

David J. Abraham, Christopher P. Denton, D. Abraham, 2010, Human pathology.

Gut fibrosis with altered colonic contractility in a mouse model of scleroderma.

C. Denton, X. Shi-wen, A. Dooley, 2012, Rheumatology.

Selective deletion of connective tissue growth factor attenuates experimentally-induced pulmonary fibrosis and pulmonary arterial hypertension

D. Abraham, C. Denton, A. Holmes, 2021, The international journal of biochemistry & cell biology.

Limited cutaneous systemic sclerosis skin demonstrates distinct molecular subsets separated by a cardiovascular development gene expression signature

Tammara A. Wood, M. Whitfield, C. Campochiaro, 2017, Arthritis Research & Therapy.

Targeting of Cholecystokinin B/gastrin receptor in cancer cell lines

S. Watson, P. Clarke, K. Savage, 2006 .

Aortic Smooth Muscle Cells Show a Pro-Fibrotic Phenotype in a TGF-Beta Dependant Mouse Model of Systemic Sclerosis.

X. Shi-wen, A. Dooley, C. Denton, 2009 .

Letter in response to article: a pilot study examining circulating interleukin-6 and transforming growth factor-β levels during pelvic radiation therapy.

D. Abraham, L. Wedlake, K. Thomas, 2013, American Journal of Clinical Oncology.

Expression of parathyroid hormone-related peptide and its receptor in neuroendocrine tumours

K. Savage, M. Caplin, M. Stubbs, 2003 .

Focal adhesion kinase and reactive oxygen species contribute to the persistent fibrotic phenotype of lesional scleroderma fibroblasts.

M. Baron, D. Abraham, C. Denton, 2012, Rheumatology.

Data on CUX1 isoforms in idiopathic pulmonary fibrosis lung and systemic sclerosis skin tissue sections

C. Morimoto, D. Abraham, C. Denton, 2016, Data in brief.

An open-label pilot study of infliximab therapy in diffuse cutaneous systemic sclerosis

C. Denton, P. Carreira, C. Black, 2008, Annals of the rheumatic diseases.

Expression of c-kit (CD117) in neuroendocrine tumours--a target for therapy?

D. Hochhauser, A. Quaglia, K. Savage, 2003, Oncology Report.