Xiaobo He

发表

Genotoxicity evaluation using primary hepatocytes isolated from rhesus macaque (Macaca mulatta).

N. Mei, J. Talpos, M. Bryant, 2021, Toxicology.

Synergistic Therapeutic Effects of Low Dose Decitabine and NY-ESO-1 Specific TCR-T Cells for the Colorectal Cancer With Microsatellite Stability

T. Wan, Yanfeng Wu, Wenying Wang, 2022, Frontiers in Oncology.

Cpt1c regulated by AMPK promotes papillary thyroid carcinomas cells survival under metabolic stress conditions

Dongwei Su, Yuelei Chen, Xinyu Zhou, 2017, Journal of Cancer.

The genotoxicity potential of luteolin is enhanced by CYP1A1 and CYP1A2 in human lymphoblastoid TK6 cells.

Lei Guo, N. Mei, K. Witt, 2021, Toxicology letters.

Driving neoantigen-based cancer vaccines for personalized immunotherapy into clinic: A burdensome journey to promising land.

Yanfeng Wu, Xing Li, Xiaobo He, 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Genotoxicity evaluation of nitrosamine impurities using human TK6 cells transduced with cytochrome P450s

N. Mei, D. Keire, M. Bryant, 2022, Archives of Toxicology.

In Vivo Pharmacokinetic Analyses of Placental Transfer of Three Drugs of Different Physicochemical Properties in Pregnant Rats.

J. Fisher, N. Nakamura, M. Bryant, 2022, Reproductive toxicology.

Formation of DHP-DNA Adducts from Rat Liver Microsomal Metabolism of 1,2-Unsaturated Pyrrolizidine Alkaloid-Containing Plant Extracts and Dietary Supplements.

P. Fu, Q. Xia, Yisheng He, 2023, Chemical research in toxicology.

Metabolism of carcinogenic pyrrolizidine alkaloids and pyrrolizidine alkaloid N-oxides by rat primary hepatocytes generate the same characteristic DHP-DNA adducts

Q. Shi, P. Fu, Q. Xia, 2021, Journal of environmental science and health. Part C, Toxicology and carcinogenesis.

1-Formyl-7-hydroxy-6,7-dihydro-5 H-pyrrolizine (1-CHO-DHP): A Potential Proximate Carcinogenic Metabolite of Pyrrolizidine Alkaloids.

G. Lin, P. Fu, Q. Xia, 2019, Chemical research in toxicology.

Pyrrolizidine Alkaloid Secondary Pyrrolic Metabolites Construct Multiple Activation Pathways Leading to DNA Adduct Formation and Potential Liver Tumor Initiation.

P. Fu, Q. Xia, Shoujun Chen, 2018, Chemical research in toxicology.

1-Formyl-7-hydroxy-6,7-dihydro-5H-pyrrolizine (1-CHO-DHP)-cysteine Conjugates - Metabolic Formation and Binding to Cellular DNA.

P. Fu, Q. Xia, Yuewei Zhao, 2020, Chemical research in toxicology.

Pyrrolizidine alkaloid-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N-oxides

G. Lin, P. Fu, Q. Xia, 2017, Journal of food and drug analysis.

7-Glutathione-pyrrole and 7-cysteine-pyrrole are potential carcinogenic metabolites of pyrrolizidine alkaloids

P. Fu, Q. Xia, Xiaobo He, 2017, Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews.

7-glutathione pyrrole adduct: a potential DNA reactive metabolite of pyrrolizidine alkaloids.

P. Fu, Q. Xia, Liang Ma, 2015, Chemical research in toxicology.

Effects of glutathione and cysteine on pyrrolizidine alkaloid-induced hepatotoxicity and DNA adduct formation in rat primary hepatocytes.

Q. Shi, P. Fu, Q. Xia, 2020, Journal of environmental science and health. Part C, Toxicology and carcinogenesis.

Quantitation of DNA reactive pyrrolic metabolites of senecionine - A carcinogenic pyrrolizidine alkaloid by LC/MS/MS analysis.

Q. Shi, G. Lin, P. Fu, 2020, Journal of food and drug analysis.

Primary and secondary pyrrolic metabolites of pyrrolizidine alkaloids form DNA adducts in human A549 cells.

W. Tolleson, G. Lin, P. Fu, 2019, Toxicology in vitro : an international journal published in association with BIBRA.

7-N-Acetylcysteine-pyrrole conjugate—A potent DNA reactive metabolite of pyrrolizidine alkaloids

P. Fu, Q. Xia, Xiaobo He, 2016, Journal of food and drug analysis.

7-cysteine-pyrrole conjugate: A new potential DNA reactive metabolite of pyrrolizidine alkaloids

P. Fu, Q. Xia, Xiaobo He, 2016, Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews.

Evaluation of pyrrolizidine alkaloid-induced genotoxicity using metabolically competent TK6 cell lines.

Lei Guo, N. Mei, K. Witt, 2020, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Evaluation of an in vitro three-dimensional HepaRG spheroid model for genotoxicity testing using the high-throughput CometChip platform.

N. Mei, M. Manjanatha, L. Muskhelishvili, 2022, ALTEX.

A UPLC-MRM-MS method for comprehensive profiling of Amadori compound-modified phosphatidylethanolamines in human plasma

Qibin Zhang, Zhucui Li, Xiaobo He, 2020, Analytical and Bioanalytical Chemistry.

Comprehensive Identification of Amadori Compound-Modified Phosphatidylethanolamines in Human Plasma.

Guan-Yuan Chen, Qibin Zhang, Xiaobo He, 2019, Chemical research in toxicology.

Synthesis, Purification, and Mass Spectrometric Characterization of Stable Isotope-Labeled Amadori-Glycated Phospholipids

Qibin Zhang, Xiaobo He, 2018, ACS omega.