Jian Wang

发表

Proteolysis targeting chimera (PROTAC) in drug discovery paradigm: Recent progress and future challenges.

Zhimin Zhang, Wenhai Huang, Xiaoliang Zheng, 2020, European journal of medicinal chemistry.

Structure activity relationships of chrysoeriol and analogs as dual c ‐ Met and VEGFR 2 tyrosine kinase inhibitors

Haixiong Jiang, Xiangxiu Zhang, Junsheng Chen, 2018 .

Synthesis and bioevaluation of N,4-diaryl-1,3-thiazole-2-amines as tubulin inhibitors with potent antiproliferative activity

Jian Wang, Kai Bao, Daiying Zuo, 2017, PloS one.

Discovery, Optimization, and Evaluation of Potent and Highly Selective PI3Kγ-PI3Kδ Dual Inhibitors.

J. Edwards, T. Rao, S. Bembenek, 2019, Journal of medicinal chemistry.

Design and synthesis of 5-aryl-pyridone-carboxamides as inhibitors of anaplastic lymphoma kinase.

Rongshi Li, Jian Wang, Rongshi Li, 2006, Journal of medicinal chemistry.

Discovery and SAR of novel 4-thiazolyl-2-phenylaminopyrimidines as potent inhibitors of spleen tyrosine kinase (SYK).

Jian Wang, G. Bemis, F. Salituro, 2008, Bioorganic & medicinal chemistry letters.

Heterobiaryl human immunodeficiency virus entry inhibitors.

D. Bolognesi, S. Fisher, M. Greenberg, 2009, Journal of medicinal chemistry.

Synthesis and evaluation of NS5A inhibitors containing diverse heteroaromatic cores.

L. Chan, S. Das, Oswy Z. Pereira, 2015, Bioorganic & medicinal chemistry letters.

Design and Synthesis of a Novel Series of Orally Bioavailable, CNS-Penetrant, Isoform Selective Phosphoinositide 3-Kinase γ (PI3Kγ) Inhibitors with Potential for the Treatment of Multiple Sclerosis (MS).

J. Griffith, V. Damagnez, S. Mahajan, 2018, Journal of medicinal chemistry.

Discovery of VX-509 (Decernotinib): A Potent and Selective Janus Kinase 3 Inhibitor for the Treatment of Autoimmune Diseases.

F. Salituro, Hui-Sheng Huang, Edmund M. Harrington, 2015, Journal of medicinal chemistry.

Discovery of (S)-1-(1-(Imidazo[1,2-a]pyridin-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazine (volitinib) as a highly potent and selective mesenchymal-epithelial transition factor (c-Met) inhibitor in clinical development for treatment of cancer.

Weiguo Qing, Y. Sai, Yumin Cui, 2014, Journal of medicinal chemistry.

Design and Synthesis of Human Immunodeficiency Virus Entry Inhibitors: Sulfonamide as an Isostere for the α-Ketoamide Group

Rongshi Li, D. Bolognesi, S. Fisher, 2007 .

Generation of New Synthetic Scaffolds Using Framework Libraries Selected and Refined via Medicinal Chemist Synthetic Expertise

Jian Wang, Alain Deschênes, Thomas R. Webb, 2008, J. Chem. Inf. Model..