Shang-Jung Cheng

Crystal structures and functional analysis of the ZnF5-WWE1-WWE2 region of PARP13/ZAP define a new mode of engaging poly(ADP-ribose)

J. Pascal, H. Soufari, A. Leung, 2021, bioRxiv.

ELTA: Enzymatic Labeling of Terminal ADP-Ribose.

D. Filippov, L. Joshua-Tor, S. Ong, 2019, Molecular cell.

ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence

D. Filippov, D. Griffin, A. Leung, 2017, Proceedings of the National Academy of Sciences.

Mitochondrial PARP1 regulates NAD+-dependent poly ADP-ribosylation of mitochondrial nucleoids

V. Bohr, A. Leung, D. Croteau, 2022, Experimental & Molecular Medicine.

Crystal structures and functional analysis of the ZnF5-WWE1-WWE2 region of PARP13/ZAP define a distinctive mode of engaging poly(ADP-ribose)

J. Pascal, H. Soufari, A. Leung, 2022, Cell reports.

Loss of the tumor suppressor BTG3 drives a pro-angiogenic tumor microenvironment through HIF-1 activation

S. Shieh, Yu-Che Cheng, Shang-Jung Cheng, 2020, Cell Death & Disease.

High-Throughput Activity Assay for Screening Inhibitors of the SARS-CoV-2 Mac1 Macrodomain

A. Jayabalan, A. Leung, T. Tsukamoto, 2021, bioRxiv.

ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence

D. Filippov, D. Griffin, A. Leung, 2017, Proceedings of the National Academy of Sciences.