Ashu Gupta

Design, synthesis and optimization of bis-amide derivatives as CSF1R inhibitors.

A. K. Agarwal, C. Higgs, S. Bernales, 2017, Bioorganic & medicinal chemistry letters.

Temozolomide analogs with improved brain/plasma ratios - Exploring the possibility of enhancing the therapeutic index of temozolomide.

Vikas Dixit, Emma McCullagh, D. T. Hung, 2016, Bioorganic & medicinal chemistry letters.

Hierarchical Phosphorylation within the Ankyrin Repeat Domain Defines a Phosphoregulatory Loop That Regulates Notch Transcriptional Activity*

Hong Wang, A. Capobianco, Prathibha Ranganathan, 2011, The Journal of Biological Chemistry.

Discovery of MDV6058 (PF-06952229), a Selective and Potent TGFβR1 Inhibitor: Design, Synthesis and Optimization.

S. Soni, S. Bernales, K. Mukherjee, 2022, Bioorganic & medicinal chemistry letters.

Targeting prostate cancer with compounds possessing dual activity as androgen receptor antagonists and HDAC6 inhibitors.

Devleena Shivakumar, J. Lindquist, D. T. Hung, 2016, Bioorganic & medicinal chemistry letters.

Novel 3-methylindoline inhibitors of EZH2: Design, synthesis and SAR.

D. Severance, D. T. Hung, S. Bernales, 2017, Bioorganic & medicinal chemistry letters.

Targeting prostate cancer with compounds possessing dual activity as androgen receptor antagonists and HDAC6 inhibitors.

Devleena Shivakumar, J. Lindquist, S. Bernales, 2016, Bioorganic & medicinal chemistry letters.

Discovery of Pyrazolopyrimidine Derivatives as Novel Dual Inhibitors of BTK and PI3Kδ.

Emma McCullagh, S. Bernales, Anamika Thakur, 2016, ACS medicinal chemistry letters.