Maria Szaruga

发表

Cellular responses to halofuginone reveal a vulnerability of the GCN2 branch of the integrated stress response

S. Wingett, A. Bertolotti, A. P. Pitera, 2022, The EMBO journal.

Aβ profiles generated by Alzheimer’s disease causing PSEN1 variants determine the pathogenicity of the mutation and predict age at disease onset

Nick C Fox, R. Vandenberghe, L. Chávez-Gutiérrez, 2022, Molecular Psychiatry.

Alzheimer’s-causing mutations shift Aβ length by destabilizing γ-secretase-Aβn interactions

Nick C Fox, B. Strooper, C. Hopf, 2021, Cell.

Destabilized γ-Secretase-Aβn interactions cause Alzheimer’s disease, implications for drug discovery

Nick C Fox, B. Strooper, C. Hopf, 2017 .

Mechanisms of neurodegeneration - Insights from familial Alzheimer's disease.

L. Chávez-Gutiérrez, Maria Szaruga, 2020, Seminars in cell & developmental biology.

Trisomy of human chromosome 21 enhances amyloid-β deposition independently of an extra copy of APP

Dean Nizetic, Andre Strydom, Henrik Zetterberg, 2018, Brain : a journal of neurology.

Alzheimer’s-Causing Mutations Shift Aβ Length by Destabilizing γ-Secretase-Aβn Interactions

N. Fox, B. Strooper, C. Hopf, 2017, Cell.

Qualitative changes in human γ-secretase underlie familial Alzheimer’s disease

Nick C Fox, B. de Strooper, A. Lleó, 2015, The Journal of experimental medicine.

Prodromal Alzheimer’s Disease: Constitutive Upregulation of Neuroglobin Prevents the Initiation of Alzheimer’s Pathology

L. Chávez-Gutiérrez, T. Saido, M. Calero, 2020, Frontiers in Neuroscience.

Spastic paraplegia preceding PSEN1‐related familial Alzheimer's disease

I. Blumcke, N. Wood, L. Chávez-Gutiérrez, 2021, Alzheimer's & dementia.

Deletion of exons 9 and 10 of the Presenilin 1 gene in a patient with Early-onset Alzheimer Disease generates longer amyloid seeds

B. Strooper, D. Campion, D. Wallon, 2017, Neurobiology of Disease.