L. Gingipalli

发表

Discovery of PROTAC molecules that selectively degrade the IRAK3 pseudokinase.

Fiona Pachl, O. Tavana, S. Degorce, 2020, Journal of medicinal chemistry.

Development of enzymatic probes of oxidative and nitrosative DNA damage caused by reactive nitrogen species.

J. Cloutier, T. O'Connor, P. Dedon, 2006, Mutation research.

The Development and Scale-Up of an Antibody Drug Conjugate Tubulysin Payload

David W. Anderson, Beatrice A. Maltman, J. Parker, 2017 .

Discovery of 2,6-disubstituted pyrazine derivatives as inhibitors of CK2 and PIM kinases.

A. Ferguson, P. Lyne, N. Larsen, 2018, Bioorganic & medicinal chemistry letters.

Pyrimidinone nicotinamide mimetics as selective tankyrase and wnt pathway inhibitors suitable for in vivo pharmacology.

S. Kazmirski, Nancy Su, D. Ogg, 2015, ACS medicinal chemistry letters.

Structure-Cytotoxicity Relationships of Analogues of N14-Desacetoxytubulysin H.

V. Bedian, Fengjiang Wang, A. Kamal, 2016, Journal of medicinal chemistry.

Photoredox Catalysis: 1,4-Conjugate Addition of N-Methyl Radicals to Electron-Deficient Olefins via Decarboxylation of N-Substituted Acetic Acids.

S. Tentarelli, A. Gopalsamy, H. Hatoum-Mokdad, 2020, Organic letters.

Preparation of highly functionalized 1,5-disubstituted tetrazoles via palladium-catalyzed Suzuki coupling

E. Hennessy, V. Hoesch, Sudhir M. Hande, 2017 .

Reaction of cis- and trans-2-Butene-1,4-dial with 2'-deoxycytidine to form stable oxadiazabicyclooctaimine adducts.

P. Dedon, L. Gingipalli, 2001, Journal of the American Chemical Society.

Discovery of azabenzimidazole derivatives as potent, selective inhibitors of TBK1/IKKε kinases.

C. Chuaqui, J. Tucker, N. Larsen, 2012, Bioorganic & medicinal chemistry letters.

Utilization of Structure-Based Design to Identify Novel, Irreversible Inhibitors of EGFR Harboring the T790M Mutation.

E. Hennessy, C. Chuaqui, J. Debreczeni, 2016, ACS medicinal chemistry letters.

Optimization of a Series of Potent, Selective and Orally Bioavailable SYK Inhibitors.

David M. Wilson, Peng-Fei Wang, S. Fawell, 2009, Bioorganic & medicinal chemistry letters.

Negishi cross-coupling enabled synthesis of novel NAD(+)-dependent DNA ligase inhibitors and SAR development.

Matthew D. Miller, M. Gowravaram, C. Eyermann, 2015, Bioorganic & medicinal chemistry letters.

From fragments to leads: novel bacterial NAD+-dependent DNA ligase inhibitors

Matthew D. Miller, C. Eyermann, L. Otterbein, 2015 .

Reaction of 2'-deoxyribonucleosides with cis- and trans-1,4-dioxo-2-butene.

Tonika Bohnert, Peter C Dedon, P. Dedon, 2004, Biochemical and biophysical research communications.

Photocatalyzed Decarboxylative Addition of N-Substituted Acetic Acids to Aldehydes.

S. Tentarelli, A. Gopalsamy, Bo Peng, 2023, The Journal of organic chemistry.

Discovery of 6-aryl-azabenzimidazoles that inhibit the TBK1/IKK-ε kinases.

C. Chuaqui, Hai‐Jun Zhang, Audrey Molina, 2014, Bioorganic & medicinal chemistry letters.

Discovery of 6-aryl-azabenzimidazoles that inhibit the TBK1/IKK-ε kinases.

C. Chuaqui, Hai‐Jun Zhang, Audrey Molina, 2014, Bioorganic & medicinal chemistry letters.