Yu Wang

Shifting paradigms in Hedgehog signaling.

A. McMahon, Benjamin L. Allen, Yu Wang, 2007, Current opinion in cell biology.

Glucocorticoid compounds modify smoothened localization and hedgehog pathway activity.

A. McMahon, L. Rubin, T. Curran, 2012, Chemistry & biology.

An eight residue fragment of an acyl carrier protein suffices for post-translational introduction of fluorescent pantetheinyl arms in protein modification in vitro and in vivo.

A. McMahon, C. Walsh, Zhe Zhou, 2008, Journal of the American Chemical Society.

A novel site comes into sight

A. McMahon, Yu Wang, 2013, eLife.

Oxysterols modulate the Hedgehog signalling pathway by binding a novel site on the membrane protein Smoothened, which may offer new options for the treatment of cancers linked to this pathway.

P. Ingham, A. McMahon, C. Siebold, 2013 .

Selective identification of hedgehog pathway antagonists by direct analysis of smoothened ciliary translocation.

A. McMahon, L. Rubin, L. Davidow, 2012, ACS chemical biology.

Selective translocation of intracellular Smoothened to the primary cilium in response to Hedgehog pathway modulation

A. McMahon, C. Walsh, Zhe Zhou, 2009, Proceedings of the National Academy of Sciences.

An eight residue fragment of an acyl carrier protein suffices for post-translational introduction of fluorescent pantetheinyl arms in protein modification in vitro and in vivo.

A. McMahon, C. Walsh, Zhe Zhou, 2008, Journal of the American Chemical Society.