Ashley Summers

Esc2 orchestrates substrate-specific sumoylation by acting as a SUMO E2 cofactor in genome maintenance

Xiaolan Zhao, Xiaoyu Xue, B. Wan, 2021, Genes & development.

Di-valent siRNA Mediated Silencing of MSH3 Blocks Somatic Repeat Expansion in Mouse Models of Huntington’s Disease

M. DiFiglia, A. Khvorova, N. Aronin, 2022, bioRxiv.

Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo

A. Khvorova, N. Aronin, E. Sapp, 2023, Research square.

Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo.

A. Khvorova, N. Aronin, E. Sapp, 2023, bioRxiv.

Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin

A. Khvorova, J. Richmond, Ken Okamura, 2023, Nature communications.

A programmable dual-targeting siRNA scaffold supports potent two-gene modulation in the central nervous system

E. Sapp, Dimas Echeverria, Ashley Summers, 2024, Nucleic acids research.