W. Elgaher

发表

Staphylococcus aureus in a wound–infection model

R. Hartmann, M. Bischoff, Murakami, 2020 .

Evaluation of Bacterial RNA Polymerase Inhibitors in a Staphylococcus aureus-based Wound-Infection Model in SKH1 Mice.

K. Murakami, R. Hartmann, M. Bischoff, 2020, ACS infectious diseases.

Discovery of Small-Molecule Stabilizers of 14-3-3 Protein-Protein Interactions via Dynamic Combinatorial Chemistry.

C. Ottmann, A. Hirsch, S. A. Andrei, 2020, ACS medicinal chemistry letters.

Design, Synthesis, Antimicrobial Activity, and Molecular Docking of Some New Diclofenac Derivatives

A. Saddik, A. Hirsch, A. K. Kamal El‐Dean, 2022, Polycyclic Aromatic Compounds.

A hydrogel-based in vitro assay for the fast prediction of antibiotic accumulation in Gram-negative bacteria

R. Hartmann, M. Vielhaber, O. Kalinina, 2020, Materials today. Bio.

Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism

K. Büssow, S. Pleschka, W. Blankenfeldt, 2022, Nature Metabolism.

Synthetic studies of cystobactamids as antibiotics and bacterial imaging carriers lead to compounds with high in vivo efficacy

R. Hartmann, R. Müller, J. van den Heuvel, 2019, Chemical science.

Bacterial RNAP Inhibitors: Synthesis and Evaluation of Prodrugs of Aryl‐ureidothiophene‐carboxylic acids

R. Hartmann, Jörg Haupenthal, C. Meier, 2017 .

Potential Dental Biofilm Inhibitors: Dynamic Combinatorial Chemistry Affords Sugar‐Based Molecules that Target Bacterial Glucosyltransferase

L. Dijkhuizen, V. R. Jumde, A. Hirsch, 2020, Chemmedchem.

Expanding the scaffold for bacterial RNA polymerase inhibitors: design, synthesis and structure–activity relationships of ureido-heterocyclic-carboxylic acids

R. Hartmann, Jörg Haupenthal, Matthias F. Groh, 2014 .

Hit-optimization using target-directed dynamic combinatorial chemistry: development of inhibitors of the anti-infective target 1-deoxy-d-xylulose-5-phosphate synthase†

N. Reiling, Jörg Haupenthal, A. Hirsch, 2020, Chemical Science.

Reversible immobilization of a protein to a gold surface through multiple host-guest interactions.

G. Wenz, A. Hirsch, Dennis H Schwarz, 2019, Journal of materials chemistry. B.

Discovery of Novel Latency-Associated Nuclear Antigen Inhibitors as Antiviral Agents Against Kaposi´s Sarcoma-Associated Herpesvirus.

T. Schulz, Philine Kirsch, M. Empting, 2020, ACS chemical biology.

Evolution of novel antibiotic Scaffolds targeting the nucleic acid machineries RNA polymerase, DNA gyrase, and topoisomerase IV

W. Elgaher, 2016 .

Discovery and Structure-Based Optimization of 2-Ureidothiophene-3-carboxylic Acids as Dual Bacterial RNA Polymerase and Viral Reverse Transcriptase Inhibitors.

R. Hartmann, E. Réal, Y. Mély, 2016, Journal of medicinal chemistry.

In Vitro Model of the Gram-Negative Bacterial Cell Envelope for Investigation of Anti-Infective Permeation Kinetics.

R. Hartmann, F. Beckmann, C. Lehr, 2018, ACS infectious diseases.

Design and synthesis of some new theophylline derivatives with bronchodilator and antibacterial activities

Ola I A Salem, A. Hayallah, A. M. A. Abdel Alim, 2011, Archives of pharmacal research.

Surface plasmon resonance--more than a screening technology: insights in the binding mode of σ70:core RNAP inhibitors.

R. Hartmann, Joerg Haupenthal, Stefan Hinsberger, 2014, Future medicinal chemistry.

Synthesis and Biological Evaluation of Cystobactamid 507: A Bacterial Topoisomerase Inhibitor from Cystobacter sp.

R. Hartmann, A. Kirschning, R. Müller, 2015, Synlett.

Cystobactamid 507: Concise Synthesis, Mode of Action, and Optimization toward More Potent Antibiotics

R. Hartmann, A. Kirschning, R. Müller, 2020, Chemistry.

Semisynthesis and biological evaluation of amidochelocardin derivatives as broad-spectrum antibiotics.

R. Hartmann, R. Müller, M. Stadler, 2019, European journal of medicinal chemistry.

NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner

S. Pleschka, Mahmoud M. Shehata, F. Pessler, 2023, bioRxiv.

Spray-drying of inhalable, multifunctional formulations for the treatment of biofilms formed in cystic fibrosis.

T. Rades, Marc Schneider, Jörg Haupenthal, 2019, Journal of controlled release : official journal of the Controlled Release Society.

Protein‐Templated Hit Identification through an Ugi Four‐Component Reaction**

W. Blankenfeldt, R. Müller, M. Köck, 2020, Chemistry.

Identification of N,N-arylalkyl-picolinamide derivatives targeting the RNA-binding protein HuR, by combining biophysical fragment-screening and molecular hybridization.

F. Vasile, D. Rossi, S. Collina, 2021, Bioorganic chemistry (Print).

Clean Synthetic Strategies to Biologically Active Molecules from Lignin: A Green Path to Drug Discovery.

Jörg Haupenthal, A. Hirsch, A. M. Kany, 2023, Angewandte Chemie.

Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways

Esben B. Svenningsen, Markus M. Rinschen, J. Diallo, 2024, Nature communications.

Novel and Extremely Sensitive NiAl2O4-NiO Nanostructures on an ITO Sensing Electrode for Enhanced Detection of Ascorbic Acid

A. Bardaoui, O. Messaoud, Shimaa Eissa, 2024, Molecules.